ES423629A1 - Preparation of 2,5-disubsituted benzamides - Google Patents

Preparation of 2,5-disubsituted benzamides

Info

Publication number
ES423629A1
ES423629A1 ES423629A ES423629A ES423629A1 ES 423629 A1 ES423629 A1 ES 423629A1 ES 423629 A ES423629 A ES 423629A ES 423629 A ES423629 A ES 423629A ES 423629 A1 ES423629 A1 ES 423629A1
Authority
ES
Spain
Prior art keywords
formula
radical
molecular weight
alcoholic
low molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423629A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Original Assignee
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes Scientifiques et Industrielles de lIle de France SA filed Critical Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Publication of ES423629A1 publication Critical patent/ES423629A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of benzamides of the general formula: **(See formula)** as well as their addition salts with pharmaceutically acceptable mineral or organic acids and their quaternary ammonium salts; in which formula (I): A can be either a low molecular weight mono- or dialkoxylamino radical in which the alcohol groups can be linked together to form a ring with or without nitrogen, oxygen or sulfur; when the ring contains a nitrogen atom, the nitrogen atom may be attached to a low molecular weight alcohol group, the rings being thus formed for example: pyrrolidinyl, piperidinyl, imidazolidinyl, piperazine, morpholino thiazolidinyl, or A is a radical heterocyclic of the form: **(See formula)** R being a low molecular weight alcoholic radical, or alcoholic; m an integer of less than 4, B can be a low molecular weight alcohol radical or an alcohol radical; n = 1 or 2; X can be an amino, mono- or dialcoylamino, alcoholic or alcoholic radical; said procedure consisting of a benzoyl chloride disubstituted in positions 2 and 5, of the formula: **(See formula)** where B and X have the same meanings as above and treat it with lead sulfocyanide, so that the corresponding benzoyl isothiocyanate is obtained, then reacting this benzoyl isothiocyanate with an amine of the formula: H2N (CH2) nA (III) where A has the same value as above, so that the desired benzamide of formula (I) is obtained. (Machine-translation by Google Translate, not legally binding)
ES423629A 1973-03-01 1974-02-26 Preparation of 2,5-disubsituted benzamides Expired ES423629A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7307434A FR2219941B1 (en) 1973-03-01 1973-03-01

Publications (1)

Publication Number Publication Date
ES423629A1 true ES423629A1 (en) 1976-06-16

Family

ID=9115666

Family Applications (1)

Application Number Title Priority Date Filing Date
ES423629A Expired ES423629A1 (en) 1973-03-01 1974-02-26 Preparation of 2,5-disubsituted benzamides

Country Status (9)

Country Link
JP (1) JPS5720946B2 (en)
AR (1) AR202294A1 (en)
AT (1) AT331223B (en)
CA (1) CA1015367A (en)
DE (1) DE2409386A1 (en)
ES (1) ES423629A1 (en)
FR (1) FR2219941B1 (en)
GB (1) GB1420574A (en)
IE (1) IE38929B1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2305176A1 (en) * 1975-03-28 1976-10-22 Ile De France NEW DRUG BASED ON N- (DIETHYLAMINOETHYL) 2-METHOXY-5-METHYL-SULFONYL BENZAMIDE

Also Published As

Publication number Publication date
AR202294A1 (en) 1975-05-30
GB1420574A (en) 1976-01-07
FR2219941B1 (en) 1977-02-04
JPS5720946B2 (en) 1982-05-04
ATA159274A (en) 1975-11-15
CA1015367A (en) 1977-08-09
IE38929B1 (en) 1978-07-05
FR2219941A1 (en) 1974-09-27
DE2409386A1 (en) 1974-09-05
JPS49134652A (en) 1974-12-25
AT331223B (en) 1976-08-10
IE38929L (en) 1974-09-01

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