ES423164A1 - Carbalkoxythioureidobenzene derivatives having anthelminitic properties - Google Patents

Carbalkoxythioureidobenzene derivatives having anthelminitic properties

Info

Publication number
ES423164A1
ES423164A1 ES423164A ES423164A ES423164A1 ES 423164 A1 ES423164 A1 ES 423164A1 ES 423164 A ES423164 A ES 423164A ES 423164 A ES423164 A ES 423164A ES 423164 A1 ES423164 A1 ES 423164A1
Authority
ES
Spain
Prior art keywords
lower alkyl
nitro
carbalkoxythioureidobenzene
derivatives
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES423164A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/434,656 external-priority patent/US4072696A/en
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of ES423164A1 publication Critical patent/ES423164A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
    • C07C335/28—Y being a hetero atom, e.g. thiobiuret

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

A method for the preparation of derivatives of carbalkoxythioureidobenzene, represented by the formula: **(See formula)** where R is a lower alkyl group having 1 to 4 carbon atoms, R1 is -SOR2, R2 is a lower alkyl having 1 to 6 carbon atoms, unsubstituted phenyl or phenyl substituted with lower alkyl, alkoxy, halo, nitro, cyano, thiocyanate, isothiocyanate, CF3, thioalkyl, alkylsulfinyl, alkylsulfonyl, acyl (1-6C), acylamino, (1-6C), -SO2NR3R4 or radicals -N (R3) SO2R4, where R3 and R4 are hydrogens or (1-6C) alkyl independently, and the pharmaceutically acceptable salts thereof; said method comprises reducing the 2-nitro group of 1- (3-carbalkoxy-2-thioureido-2-nitro-4 (5) -R1-benzene substituted to give compound I, or optionally forming a salt thereof. (Machine-translation by Google Translate, not legally binding)
ES423164A 1973-02-12 1974-02-12 Carbalkoxythioureidobenzene derivatives having anthelminitic properties Expired ES423164A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33185273A 1973-02-12 1973-02-12
US05/434,656 US4072696A (en) 1973-02-12 1974-01-18 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity

Publications (1)

Publication Number Publication Date
ES423164A1 true ES423164A1 (en) 1976-09-16

Family

ID=26987956

Family Applications (1)

Application Number Title Priority Date Filing Date
ES423164A Expired ES423164A1 (en) 1973-02-12 1974-02-12 Carbalkoxythioureidobenzene derivatives having anthelminitic properties

Country Status (11)

Country Link
JP (1) JPS5046641A (en)
BR (1) BR7401013D0 (en)
CA (1) CA1028337A (en)
DE (1) DE2462258C2 (en)
ES (1) ES423164A1 (en)
FR (2) FR2217015B1 (en)
GB (2) GB1460641A (en)
IE (1) IE38846B1 (en)
IN (1) IN139876B (en)
IT (1) IT1051603B (en)
NL (1) NL180212C (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2541742C2 (en) * 1975-09-19 1983-04-28 Hoechst Ag, 6230 Frankfurt o-Nitro-phenyl-thionocarbamoyl-carbaminate and process for their preparation
US4060636A (en) 1976-06-10 1977-11-29 Rohm And Haas Company Acetyl- and carbalkoxythioureidobenzophenones as anthelmintic agents
HU195949B (en) * 1984-02-29 1988-08-29 Richter Gedeon Vegyeszet Process for producing new nitro-diaryl-sulfoxide derivatives and pharmaceutics comprising such compounds
HU195950B (en) * 1984-02-29 1988-08-29 Richter Gedeon Vegyeszet Process for producing nitramino-diaryl-sulfoxide derivatives and pharmaceutics comprising such compounds
HU195951B (en) * 1984-02-29 1988-08-29 Richter Gedeon Vegyeszet Process for producing amino-diaryl-sulfoxide derivatives and pharmaceutics comprising such compounds
DE19829357A1 (en) 1998-07-01 2000-01-05 Bayer Ag Process for the preparation of 2-nitro-5- (phenylthio) anilines

Also Published As

Publication number Publication date
CA1028337A (en) 1978-03-21
BR7401013D0 (en) 1974-11-05
NL180212B (en) 1986-08-18
DE2406584A1 (en) 1974-09-12
GB1460642A (en) 1977-01-06
FR2217015A1 (en) 1974-09-06
NL7401797A (en) 1974-08-14
DE2406584B2 (en) 1977-03-31
AU6543374A (en) 1975-08-14
DE2462258C2 (en) 1982-01-28
FR2283126A1 (en) 1976-03-26
NL180212C (en) 1987-01-16
IT1051603B (en) 1981-05-20
GB1460641A (en) 1977-01-06
IN139876B (en) 1976-08-14
FR2217015B1 (en) 1978-07-21
IE38846B1 (en) 1978-06-07
DE2462258A1 (en) 1976-07-08
JPS5046641A (en) 1975-04-25
IE38846L (en) 1974-08-12
FR2283126B1 (en) 1980-06-27

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