ES417804A1 - Chemotherapeutic compositions - Google Patents

Chemotherapeutic compositions

Info

Publication number
ES417804A1
ES417804A1 ES417804A ES417804A ES417804A1 ES 417804 A1 ES417804 A1 ES 417804A1 ES 417804 A ES417804 A ES 417804A ES 417804 A ES417804 A ES 417804A ES 417804 A1 ES417804 A1 ES 417804A1
Authority
ES
Spain
Prior art keywords
hydrogen
nitro
formula
synergistic
chemotherapeutic compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES417804A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES417804A1 publication Critical patent/ES417804A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/70—Nitro radicals
    • C07D307/71—Nitro radicals attached in position 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/42—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms
    • C07D333/44—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms with nitro or nitroso radicals directly attached to ring carbon atoms attached in position 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Procedure for the production of synergistic antibacterial compositions; characterized by comprising bringing into synergistic association a compound of formula I, ** (See formula) ** where R1 and R2 are identical or different and each signify hydrogen, lower alkyl, lower alkoxy, nitro, amino, carboxylic acid, amide or halogen, and R3 is hydrogen, aminoalkyl, dialkylaminoalkyl, hydroxyalkyl, alkoxyalkyl, cycloalkyl, benzyl or phenethyl, assuming that all the radicals R1, R2 and R3 do not all simultaneously mean hydrogen, with a 2-nitrofuryl or 2-nitro thienyl derivative. (Machine-translation by Google Translate, not legally binding)
ES417804A 1972-08-14 1973-08-11 Chemotherapeutic compositions Expired ES417804A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1200872 1972-08-14

Publications (1)

Publication Number Publication Date
ES417804A1 true ES417804A1 (en) 1976-06-16

Family

ID=4378980

Family Applications (1)

Application Number Title Priority Date Filing Date
ES417804A Expired ES417804A1 (en) 1972-08-14 1973-08-11 Chemotherapeutic compositions

Country Status (10)

Country Link
JP (1) JPS594401B2 (en)
AT (1) AT347172B (en)
BE (1) BE803553A (en)
DD (1) DD109186A5 (en)
DE (1) DE2340709C2 (en)
ES (1) ES417804A1 (en)
FR (1) FR2196157B1 (en)
GB (1) GB1442625A (en)
HU (1) HU167371B (en)
NL (1) NL7311001A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MW7087A1 (en) * 1986-10-03 1988-05-11 Hoffmann La Roche 1,3-disubstituted imidazolium salts
DE3722886A1 (en) * 1987-07-10 1989-01-19 Basf Ag METHOD FOR THE PRODUCTION OF (ALPHA), SS-SUBSTITUTED ACROLEINS AND NEW SUBSTITUTED ACROLEINS

Also Published As

Publication number Publication date
FR2196157B1 (en) 1978-07-28
GB1442625A (en) 1976-07-14
BE803553A (en) 1974-02-13
DE2340709A1 (en) 1974-02-28
DE2340709C2 (en) 1983-12-22
DD109186A5 (en) 1974-10-20
AT347172B (en) 1978-12-11
NL7311001A (en) 1974-02-18
HU167371B (en) 1975-09-27
JPS49124062A (en) 1974-11-27
ATA705973A (en) 1978-04-15
AU5917673A (en) 1975-02-13
JPS594401B2 (en) 1984-01-30
FR2196157A1 (en) 1974-03-15

Similar Documents

Publication Publication Date Title
ES316768A1 (en) Procedure for the preparation of a new polyamide. (Machine-translation by Google Translate, not legally binding)
ES417804A1 (en) Chemotherapeutic compositions
ES347319A1 (en) A procedure for the preparation of new heterociclic aromatic compounds. (Machine-translation by Google Translate, not legally binding)
ES428005A1 (en) 3,4-Dihydro-2H-naphthalene-1-one-5-oxypropyl-piperazine compounds
ES431526A1 (en) Piperazines derivatives
ES375443A1 (en) N-(3,5-dihalogenophenyl)-oxazolidine compounds and preparation thereof
ES428600A1 (en) Diaminopropanols
ES307983A1 (en) Procedure for the preparation of new amidas of ariloxyacetic acid. (Machine-translation by Google Translate, not legally binding)
GB1032253A (en) Coumarin derivatives and process for the production thereof
GB1073976A (en) New biologically active derivatives of pyrrolidine and the manufacture thereof
ES287547A1 (en) Procedure for the production of N- (2,3-dimethylene) antranilic acid and its salts (Machine-translation by Google Translate, not legally binding)
ES462843A1 (en) Compound and production thereof
ES323103A1 (en) A procedure for the preparation of new penicillins. (Machine-translation by Google Translate, not legally binding)
ES430840A1 (en) 7-monochloroacetamido-3-desacetoxy-cephalosporanic acid derivatives their preparation and use
GB1051328A (en)
ES363295A1 (en) A procedure for preparing benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)
ES419266A1 (en) A procedure for preparing quinazoline derivatives. (Machine-translation by Google Translate, not legally binding)
ES395952A1 (en) Dihydropyrimidopyridazine derivatives
ES328626A1 (en) Procedure for the preparation of chloranphenicol esters. (Machine-translation by Google Translate, not legally binding)
ES402410A1 (en) Derivatives of 1,2-dihydro-2-oxo-4-aminopyrimido(4,5-b)quinoxaline-5,10-microndioxides
ES454098A1 (en) Procedure to produce argininamids and their salts. (Machine-translation by Google Translate, not legally binding)
ES397770A1 (en) N-alkenyltetracycline derivatives
ES263122A1 (en) A procedure for the manufacture of derivatives of 1,4-benzodiazepinas (Machine-translation by Google Translate, not legally binding)
ES295940A1 (en) A procedure for the preparation of compounds of trifenilohalo-ethylene (Machine-translation by Google Translate, not legally binding)
ES452859A1 (en) A procedure for the preparation of a penicillin. (Machine-translation by Google Translate, not legally binding)