ES413827A1 - Procedure for the preparation of N- (trans-4-hydroxiciclohexil) -2 (2-amino-3,5-dibromobencil) -amine. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of N- (trans-4-hydroxiciclohexil) -2 (2-amino-3,5-dibromobencil) -amine. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES413827A1
ES413827A1 ES413827A ES413827A ES413827A1 ES 413827 A1 ES413827 A1 ES 413827A1 ES 413827 A ES413827 A ES 413827A ES 413827 A ES413827 A ES 413827A ES 413827 A1 ES413827 A1 ES 413827A1
Authority
ES
Spain
Prior art keywords
trans
amino
translation
amine
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES413827A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES413827A1 publication Critical patent/ES413827A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Process for the preparation of N- (trans-4-hydroxycyclohexyl) - (2-amino-3,5-dibromobenzyl) -amine and its salts by addition of acid, characterized in that N- (2-amino-3 is reduced, 5-dibromobenzylidene) -trans-4-aminociolohexanol and the optionally obtained base is optionally converted into its salt by the addition of acid with a physiologically compatible organic or inorganic acid. (Machine-translation by Google Translate, not legally binding)
ES413827A 1972-04-18 1973-04-17 Procedure for the preparation of N- (trans-4-hydroxiciclohexil) -2 (2-amino-3,5-dibromobencil) -amine. (Machine-translation by Google Translate, not legally binding) Expired ES413827A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722218647 DE2218647A1 (en) 1972-04-18 1972-04-18 Secretolytic n-(trans-4-hydroxycyclohexyl)-2-amino-3,5- - dibromobenzylamine prepn - by redn of n-(2-amino-3,5-dibromobenzylide

Publications (1)

Publication Number Publication Date
ES413827A1 true ES413827A1 (en) 1976-01-16

Family

ID=5842287

Family Applications (2)

Application Number Title Priority Date Filing Date
ES413827A Expired ES413827A1 (en) 1972-04-18 1973-04-17 Procedure for the preparation of N- (trans-4-hydroxiciclohexil) -2 (2-amino-3,5-dibromobencil) -amine. (Machine-translation by Google Translate, not legally binding)
ES421120A Expired ES421120A1 (en) 1972-04-18 1973-12-04 Procedure for the preparation of N- (2-amino-3,5-dibromobenciliden) -trans-4-amino-ciclohexanol. (Machine-translation by Google Translate, not legally binding)

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES421120A Expired ES421120A1 (en) 1972-04-18 1973-12-04 Procedure for the preparation of N- (2-amino-3,5-dibromobenciliden) -trans-4-amino-ciclohexanol. (Machine-translation by Google Translate, not legally binding)

Country Status (18)

Country Link
JP (1) JPS554096B2 (en)
AT (1) AT321270B (en)
BG (1) BG22807A3 (en)
CA (1) CA1003441A (en)
CH (1) CH575907A5 (en)
CS (1) CS174876B2 (en)
DD (1) DD107261A5 (en)
DE (1) DE2218647A1 (en)
DK (2) DK139515C (en)
ES (2) ES413827A1 (en)
FI (1) FI56522C (en)
HU (1) HU165758B (en)
NO (1) NO137086C (en)
PL (1) PL86344B1 (en)
RO (1) RO65104A (en)
SE (2) SE415970B (en)
SU (1) SU458976A3 (en)
YU (1) YU35573B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2223193C3 (en) * 1972-05-12 1975-05-28 Dr. Karl Thomae Gmbh, 7950 Biberach Process for the preparation of 2-amino-benzylamines
US4020104A (en) * 1976-09-20 1977-04-26 The Upjohn Company Process for isomerizing cis,cis- and cis,trans-isomers of di-(p-aminocyclohexyl)methane to the corresponding trans,trans-isomer
DE2720867C2 (en) * 1977-05-10 1979-05-31 Kernforschungsanlage Juelich Gmbh, 5170 Juelich Method for the quantitative separation of uranium from samples of natural water
ATE22069T1 (en) * 1983-06-29 1986-09-15 Heumann Ludwig & Co Gmbh PROCESS FOR THE PREPARATION OF 2-AMINO-3,5DIBROMOBENZYLAMINES.
IT1216837B (en) * 1987-01-07 1990-03-14 Erregierre Ind Chim SALTS OF N- (TRANS-P-IDROSSI-CICLOESIL) - (2 AMINO-3,5-DIBROMO) BENZYLAMINE EQUIPPED WITH MUCOLYTIC ACTIVITY.
HU207834B (en) * 1989-12-22 1993-06-28 Egyt Gyogyszervegyeszeti Gyar Process for producing n-/2-amino-3,5-dibromo-benzyl/-trans-4-amino-cyclohexanol

Also Published As

Publication number Publication date
ES421120A1 (en) 1976-06-16
FI56522C (en) 1980-02-11
DD107261A5 (en) 1974-07-20
NO137086C (en) 1977-12-28
DK139515B (en) 1979-03-05
JPS4914443A (en) 1974-02-07
CA1003441A (en) 1977-01-11
HU165758B (en) 1974-10-28
BG22807A3 (en) 1977-04-20
JPS554096B2 (en) 1980-01-29
DK139515C (en) 1979-08-20
SE7513808L (en) 1975-12-08
RO65104A (en) 1979-08-15
DE2218647A1 (en) 1973-10-25
PL86344B1 (en) 1976-05-31
SE415970B (en) 1980-11-17
AT321270B (en) 1975-03-25
FI56522B (en) 1979-10-31
NO137086B (en) 1977-09-19
SE421613B (en) 1982-01-18
YU101773A (en) 1980-10-31
YU35573B (en) 1981-04-30
CH575907A5 (en) 1976-05-31
DK570776A (en) 1976-12-17
CS174876B2 (en) 1977-04-29
SU458976A3 (en) 1975-01-30

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