ES407563A1 - Coating materials for enteric medicaments - Google Patents

Coating materials for enteric medicaments

Info

Publication number
ES407563A1
ES407563A1 ES407563A ES407563A ES407563A1 ES 407563 A1 ES407563 A1 ES 407563A1 ES 407563 A ES407563 A ES 407563A ES 407563 A ES407563 A ES 407563A ES 407563 A1 ES407563 A1 ES 407563A1
Authority
ES
Spain
Prior art keywords
hydrogen
alkyl
see formula
copolymer
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES407563A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES407563A1 publication Critical patent/ES407563A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A procedure for the preparation of a partial ester of alkylene glycol ether and copolymer of C1-C4 alkyl acrylate and unsaturated carboxylic acid anhydride, consisting of the following sequence of reactions: a) Copolymerization of an alkyl acrylate and an unsaturated polybasic carboxylic acid anhydride in a molar ratio of between 1: 5 and 5: 1 to give a copolymer of the formula ** (See formula) ** where R is C1-C4 alkyl R2 is hydrogen or methyl R7 is hydrogen or (see formula) so that they are not the same R3 and R4 are hydrogen or the radical (see formula) where R5 is hydrogen or methyl and R6 is alkyl n2 is 0 or 1. with the proviso that about 10 to 50% of the total potential radicals R3 and R4 is other than hydrogen q is an integer from 1 to 4, n1 is an integer greater than 70 x e and are integers from 1 to 5. (Machine-translation by Google Translate, not legally binding)
ES407563A 1971-10-12 1972-10-11 Coating materials for enteric medicaments Expired ES407563A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18859171A 1971-10-12 1971-10-12

Publications (1)

Publication Number Publication Date
ES407563A1 true ES407563A1 (en) 1976-02-01

Family

ID=22693788

Family Applications (1)

Application Number Title Priority Date Filing Date
ES407563A Expired ES407563A1 (en) 1971-10-12 1972-10-11 Coating materials for enteric medicaments

Country Status (25)

Country Link
JP (1) JPS4847590A (en)
AR (1) AR194852A1 (en)
AT (2) AT316139B (en)
AU (1) AU473557B2 (en)
BE (1) BE789919A (en)
BR (1) BR7207119D0 (en)
CA (1) CA1004799A (en)
CH (1) CH575967A5 (en)
DD (2) DD103248A5 (en)
DE (1) DE2250028A1 (en)
DK (1) DK138503B (en)
ES (1) ES407563A1 (en)
FR (1) FR2157847B1 (en)
GB (1) GB1409280A (en)
HU (1) HU165803B (en)
IE (1) IE36731B1 (en)
IL (1) IL40520A (en)
IT (1) IT990509B (en)
NL (1) NL7213765A (en)
PH (1) PH13179A (en)
PL (2) PL102291B1 (en)
RO (1) RO62797A (en)
SE (2) SE400979B (en)
YU (1) YU34904B (en)
ZA (1) ZA727066B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1115596B (en) * 1978-03-13 1986-02-03 Bayer Italia Spa METHOD FOR THE PREPARATION OF GASTORESISTANT AND ENTERO-SOLUBLE MICROGRANULES OF PHARMACEUTICAL SUBSTANCES, IN PARTICULAR OF PROTEIN SUBSTANCES AND MICROGRANULES PREPARED WITH THE METHOD
GB2164339A (en) * 1984-09-11 1986-03-19 Ciba Geigy Ag Polymaleic anhydride derivatives
GB2340521B (en) * 1998-08-15 2000-09-13 Sofitech Nv Shale-stabilizing additives
AU4428000A (en) * 1999-05-14 2000-12-05 Coraltis Ltd. Pulse-delivery oral compositions
CN113855643B (en) * 2021-11-10 2022-11-11 葵花药业集团佳木斯鹿灵制药有限公司 Mesalazine sustained release preparation for colon-specific drug release and preparation process thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE575343A (en) * 1955-09-09
NL289626A (en) * 1962-03-06 1900-01-01
US3369003A (en) * 1962-03-06 1968-02-13 Sinclair Research Inc Polymers of tertiary-alkoxyalkyl esters
US3387061A (en) * 1966-05-04 1968-06-04 Union Carbide Corp Chemical reaction product of polycarboxylic acid and a polymeric polyether
GB1213030A (en) * 1968-08-16 1970-11-18 Daicel Ltd Process for producing a graft copolymer
JPS4931557A (en) * 1972-07-22 1974-03-22

Also Published As

Publication number Publication date
YU255672A (en) 1979-10-31
IE36731L (en) 1973-04-12
DE2250028A1 (en) 1973-04-19
CH575967A5 (en) 1976-05-31
YU34904B (en) 1980-04-30
JPS4847590A (en) 1973-07-06
AR194852A1 (en) 1973-08-24
AU473557B2 (en) 1976-06-24
DD109508A5 (en) 1974-11-12
PH13179A (en) 1980-01-08
FR2157847B1 (en) 1975-10-31
IL40520A (en) 1975-12-31
BE789919A (en) 1973-04-11
BR7207119D0 (en) 1973-07-19
IT990509B (en) 1975-07-10
SE7604731L (en) 1976-04-23
AT329185B (en) 1976-04-26
GB1409280A (en) 1975-10-08
PL102291B1 (en) 1979-03-31
ATA858173A (en) 1975-07-15
CA1004799A (en) 1977-02-01
AT316139B (en) 1974-06-25
AU4745172A (en) 1974-04-11
SE411123B (en) 1979-12-03
RO62797A (en) 1977-10-15
DK138503B (en) 1978-09-18
FR2157847A1 (en) 1973-06-08
IL40520A0 (en) 1972-12-29
NL7213765A (en) 1973-04-16
SE400979B (en) 1978-04-17
ZA727066B (en) 1974-05-29
DK138503C (en) 1979-02-26
HU165803B (en) 1974-11-28
PL76176B1 (en) 1975-02-28
DD103248A5 (en) 1974-01-12
IE36731B1 (en) 1977-02-02

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