ES406129A1 - Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES406129A1 ES406129A1 ES406129A ES406129A ES406129A1 ES 406129 A1 ES406129 A1 ES 406129A1 ES 406129 A ES406129 A ES 406129A ES 406129 A ES406129 A ES 406129A ES 406129 A1 ES406129 A1 ES 406129A1
- Authority
- ES
- Spain
- Prior art keywords
- general formula
- formula
- carbon atoms
- radical
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
- C07C49/813—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Procedure for the preparation of new 4- (4-biphenyl) -butyric acids and their esters of the general formula I **(See formula)** wherein R1 signifies a hydrogen or halogen atom; R2 means a halogen atom, an amino group optionally substituted by an acyl radical with 1 to 4 carbon atoms or an alcohol radical with 1 to 3 carbon atoms; and R3 means a hydrogen atom or an alcohol radical with 1 to 3 carbon atoms and, if R3 represents a hydrogen atom, its physiologically compatible salts with organic or inorganic bases, characterized in that a dithiocoetal is subjected to desulfurization of 4- (4-biphenyl) -4-oxo-butyric acid ester of the general formula II **(See formula)** wherein R1, R3, R2, are as initially defined R4 and R5 signify lower alcohol radicals or R4 and R5 together signify an alcoholic group; and, in the event that a compound of the general formula I is obtained, in which R3 represents an alcoholic radical, this is hydrolyzed, if desired, subsequently in an alkaline or acidic medium and/or, in the event that a compound of the formula is obtained General I, in which R3 represents a hydrogen atom, is converted, if desired, into a physiologically compatible salt with an organic or inorganic base or an ester of the general formula I. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19712112840 DE2112840A1 (en) | 1971-03-17 | 1971-03-17 | New 4- (4-biphenylyl) butyric acids, their salts and esters |
Publications (1)
Publication Number | Publication Date |
---|---|
ES406129A1 true ES406129A1 (en) | 1975-07-16 |
Family
ID=5801828
Family Applications (11)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES400792A Expired ES400792A1 (en) | 1971-03-17 | 1972-03-15 | Procedure for the preparation of new acids 4- (4-bifenilil) -butiricos and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406125A Expired ES406125A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406126A Expired ES406126A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406123A Expired ES406123A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406132A Expired ES406132A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406128A Expired ES406128A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406131A Expired ES406131A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406129A Expired ES406129A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406127A Expired ES406127A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406130A Expired ES406130A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406124A Expired ES406124A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
Family Applications Before (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES400792A Expired ES400792A1 (en) | 1971-03-17 | 1972-03-15 | Procedure for the preparation of new acids 4- (4-bifenilil) -butiricos and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406125A Expired ES406125A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406126A Expired ES406126A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406123A Expired ES406123A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406132A Expired ES406132A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406128A Expired ES406128A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406131A Expired ES406131A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES406127A Expired ES406127A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406130A Expired ES406130A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of 4 - (4 - bifenilil) - butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
ES406124A Expired ES406124A1 (en) | 1971-03-17 | 1972-08-26 | Procedure for the preparation of acids 4- (4-bifenilil) -butirrics and their steres. (Machine-translation by Google Translate, not legally binding) |
Country Status (7)
Country | Link |
---|---|
AT (2) | AT310725B (en) |
CH (13) | CH573894A5 (en) |
DE (1) | DE2112840A1 (en) |
DK (1) | DK132942C (en) |
ES (11) | ES400792A1 (en) |
FR (1) | FR2282866A1 (en) |
SE (1) | SE393101B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6420396B1 (en) * | 1998-12-16 | 2002-07-16 | Beiersdorf Ag | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
US6677360B2 (en) * | 1998-12-16 | 2004-01-13 | Bayer Aktiengesellschaft | Biphenyl and biphenyl-analogous compounds as integrin antagonists |
AR044152A1 (en) | 2003-05-09 | 2005-08-24 | Bayer Corp | RENTAL DERIVATIVES, METHOD OF PREPARATION AND USE FOR THE TREATMENT OF OBESITY |
-
1971
- 1971-03-17 DE DE19712112840 patent/DE2112840A1/en active Pending
-
1972
- 1972-03-14 CH CH729475A patent/CH573894A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH729275A patent/CH566959A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH371772A patent/CH574385A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH729575A patent/CH573895A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH728775A patent/CH573890A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH728475A patent/CH580050A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH729075A patent/CH566957A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH728975A patent/CH573893A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH728575A patent/CH566956A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH729375A patent/CH566960A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH729175A patent/CH566958A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH728675A patent/CH573889A5/xx not_active IP Right Cessation
- 1972-03-14 CH CH728875A patent/CH574386A5/xx not_active IP Right Cessation
- 1972-03-15 ES ES400792A patent/ES400792A1/en not_active Expired
- 1972-03-16 AT AT222372A patent/AT310725B/en not_active IP Right Cessation
- 1972-03-16 AT AT1055772A patent/AT321287B/en active
- 1972-03-16 DK DK124172A patent/DK132942C/en active
- 1972-03-16 SE SE342172A patent/SE393101B/en unknown
- 1972-08-26 ES ES406125A patent/ES406125A1/en not_active Expired
- 1972-08-26 ES ES406126A patent/ES406126A1/en not_active Expired
- 1972-08-26 ES ES406123A patent/ES406123A1/en not_active Expired
- 1972-08-26 ES ES406132A patent/ES406132A1/en not_active Expired
- 1972-08-26 ES ES406128A patent/ES406128A1/en not_active Expired
- 1972-08-26 ES ES406131A patent/ES406131A1/en not_active Expired
- 1972-08-26 ES ES406129A patent/ES406129A1/en not_active Expired
- 1972-08-26 ES ES406127A patent/ES406127A1/en not_active Expired
- 1972-08-26 ES ES406130A patent/ES406130A1/en not_active Expired
- 1972-08-26 ES ES406124A patent/ES406124A1/en not_active Expired
-
1974
- 1974-12-19 FR FR7442066A patent/FR2282866A1/en active Granted
Also Published As
Publication number | Publication date |
---|---|
CH573890A5 (en) | 1976-03-31 |
AT321287B (en) | 1975-03-25 |
CH573895A5 (en) | 1976-03-31 |
CH566959A5 (en) | 1975-09-30 |
ES406125A1 (en) | 1975-08-01 |
CH573889A5 (en) | 1976-03-31 |
CH566956A5 (en) | 1975-09-30 |
ES406127A1 (en) | 1975-07-16 |
ES406126A1 (en) | 1975-07-16 |
CH566958A5 (en) | 1975-09-30 |
FR2282866A1 (en) | 1976-03-26 |
ES406131A1 (en) | 1975-08-01 |
DE2112840A1 (en) | 1972-10-05 |
ES406130A1 (en) | 1975-07-16 |
CH566960A5 (en) | 1975-09-30 |
DK132942C (en) | 1976-08-02 |
AT310725B (en) | 1973-10-10 |
CH574386A5 (en) | 1976-04-15 |
DK132942B (en) | 1976-03-01 |
ES406132A1 (en) | 1975-07-16 |
CH574385A5 (en) | 1976-04-15 |
CH566957A5 (en) | 1975-09-30 |
ES406123A1 (en) | 1975-08-01 |
ES406128A1 (en) | 1975-07-16 |
ES400792A1 (en) | 1975-01-16 |
SE393101B (en) | 1977-05-02 |
CH573893A5 (en) | 1976-03-31 |
CH573894A5 (en) | 1976-03-31 |
FR2282866B1 (en) | 1978-07-21 |
CH580050A5 (en) | 1976-09-30 |
ES406124A1 (en) | 1975-08-01 |
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