ES401921A1 - Procedure for the obtaining of new derivatives of the 7-amino-cephaloesporanic. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of new derivatives of the 7-amino-cephaloesporanic. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES401921A1 ES401921A1 ES72401921A ES401921A ES401921A1 ES 401921 A1 ES401921 A1 ES 401921A1 ES 72401921 A ES72401921 A ES 72401921A ES 401921 A ES401921 A ES 401921A ES 401921 A1 ES401921 A1 ES 401921A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compounds
- group
- ester
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
Procedure for obtaining new derivatives of 7-amino-cephaloesporanic acid, of formula I **(See formula)** wherein R1 means an aminopyridine residue and R2 means an aromatic heterocyclic residue, linked through a carbon atom to the sulfur, which contains at least 2 nitrogen atoms and also a further heteroatom of the nitrogen, oxygen and sulfur group, or the esters or salts of these compounds; characterized in that a) a compound-of formula II **(See formula)** wherein Z represents the acyl radical R1'-CH2-CO-, where R1'represents an aminopyridine radical, optionally protected by a dissociable protecting group and where R2' represents a functionally modified, especially esterified, hydroxy group or an ester or a salt of these compounds, are reacted with a thiol of formula Ib **(See formula)** wherein R2 has the meaning indicated in formula I, or a metal salt thereof, or b) a compound of formula II, where Z means an esterified hydroxyacetyl group, capable of reaction and R2'means S-R2- or a salt or an ester of these compounds, are reacted with an aminopyridine, optionally protected by a dissociable protecting group, or c) a compound of formula II where Z is hydrogen and is S-R2 or a salt or ester of these compounds, they are reacted with acylating agent, bearing the acyl residue Z; and in the compounds obtained with an amino group, the protecting group is dissociated; and, if desired, an ester group, if any existing, dissociates and, if desired, the obtained compounds are transformed into their salts or from the obtained salts the internal salts are formed. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES72401921A ES401921A1 (en) | 1972-04-19 | 1972-04-19 | Procedure for the obtaining of new derivatives of the 7-amino-cephaloesporanic. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES72401921A ES401921A1 (en) | 1972-04-19 | 1972-04-19 | Procedure for the obtaining of new derivatives of the 7-amino-cephaloesporanic. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES401921A1 true ES401921A1 (en) | 1976-05-16 |
Family
ID=8460928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES72401921A Expired ES401921A1 (en) | 1972-04-19 | 1972-04-19 | Procedure for the obtaining of new derivatives of the 7-amino-cephaloesporanic. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES401921A1 (en) |
-
1972
- 1972-04-19 ES ES72401921A patent/ES401921A1/en not_active Expired
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