ES399870A1 - 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation - Google Patents
1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparationInfo
- Publication number
- ES399870A1 ES399870A1 ES399870A ES399870A ES399870A1 ES 399870 A1 ES399870 A1 ES 399870A1 ES 399870 A ES399870 A ES 399870A ES 399870 A ES399870 A ES 399870A ES 399870 A1 ES399870 A1 ES 399870A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- group
- hydrogen
- alcohol
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-alcoholylaminopropanes of the general formula ** (See formula) ** where R1 means a radical with the partial formula (CH2) x-CN, (CH2) x-NH2 or (CH2) x + 1-OH, (where x means zero or an integer from 1 to 3), COOR5 (where R5 signifies hydrogen or an alcohol radical with 1 to 4 carbon atoms), an alkenyl, alkynyl, alkenyloxy or alkynyloxy radical with 2 to 5 carbon atoms; R2 means hydrogen, halogen, an alcohol or alkoxy group with 1 to 4 carbon atoms, an alkenyl group with 2 to 5 carbon atoms, a cyano or nitro group or, together with R1, means the 3,4-methylenedioxy group; R3 means hydrogen, halogen or an alcohol or alkoxy group with 1 to 4 carbon atoms; and R4 means a straight or branched chain hydroxyalkyl group with 3 to 6 carbon atoms, characterized in that in a compound of the general formula ** (See formula) ** in which R1 to R4 have the meanings mentioned above and Sch means a protective group easily separable by hydrogenolysis or hydrolysis, the Sch group is replaced by hydrogenolytic or hydrolytic route, by hydrogen; and if desired, the compounds obtained are transformed into their salts by the addition of physiologically compatible acid or esters. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19702048838 DE2048838A1 (en) | 1970-10-05 | 1970-10-05 | New 1 phenoxy 2 hydroxy 3 hydroxyal kylaminopropane and process for their manufacture |
Publications (1)
Publication Number | Publication Date |
---|---|
ES399870A1 true ES399870A1 (en) | 1975-07-16 |
Family
ID=5784228
Family Applications (8)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES395671A Expired ES395671A1 (en) | 1970-10-05 | 1971-10-04 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399871A Expired ES399871A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399872A Expired ES399872A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399873A Expired ES399873A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399874A Expired ES399874A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399868A Expired ES399868A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399869A Expired ES399869A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399870A Expired ES399870A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
Family Applications Before (7)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES395671A Expired ES395671A1 (en) | 1970-10-05 | 1971-10-04 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399871A Expired ES399871A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399872A Expired ES399872A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399873A Expired ES399873A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399874A Expired ES399874A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399868A Expired ES399868A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
ES399869A Expired ES399869A1 (en) | 1970-10-05 | 1972-02-17 | 1-phenoxy-2-hydroxy-3-hydroxyalkylamino-propanes an processes for their preparation |
Country Status (26)
Country | Link |
---|---|
JP (1) | JPS5710097B1 (en) |
AT (10) | AT318572B (en) |
AU (1) | AU469119B2 (en) |
BE (1) | BE773472A (en) |
BG (8) | BG20100A3 (en) |
CA (1) | CA1008866A (en) |
CH (11) | CH587223A5 (en) |
CS (2) | CS172932B2 (en) |
DE (1) | DE2048838A1 (en) |
DK (1) | DK130958B (en) |
ES (8) | ES395671A1 (en) |
FI (1) | FI55491C (en) |
FR (1) | FR2110230B1 (en) |
GB (1) | GB1364280A (en) |
HU (1) | HU163226B (en) |
IE (1) | IE35693B1 (en) |
IL (1) | IL37830A (en) |
NL (1) | NL174249C (en) |
NO (1) | NO132835C (en) |
PH (1) | PH9959A (en) |
PL (10) | PL84224B1 (en) |
RO (8) | RO62357A (en) |
SE (1) | SE383631B (en) |
SU (2) | SU419024A3 (en) |
YU (2) | YU35576B (en) |
ZA (1) | ZA716643B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4055658A (en) * | 1976-05-17 | 1977-10-25 | Mead Johnson & Company | Cyanomethylphenethanolamines |
US4454154A (en) * | 1981-06-23 | 1984-06-12 | American Hospital Supply Corporation | Method for treating glaucoma by the topical administration of selectively metabolized beta-blocking agents |
DE3248835A1 (en) * | 1981-06-23 | 1983-06-30 | American Hospital Supply Corp | COMPOSITIONS FOR TREATING GLAUCOMA |
US4652584A (en) * | 1984-07-13 | 1987-03-24 | Mcneilab, Inc. | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension |
DE4422707A1 (en) * | 1994-06-29 | 1996-01-04 | Hoechst Ag | Process for dyeing aminated cellulose / polyester blends with fiber-reactive disperse dyes |
JP4934287B2 (en) * | 2005-04-05 | 2012-05-16 | 花王株式会社 | Whitening agent |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DD45360A (en) * | ||||
CA945172A (en) * | 1969-02-21 | 1974-04-09 | Imperial Chemical Industries Limited | Alkanolamine derivatives |
-
1970
- 1970-10-05 DE DE19702048838 patent/DE2048838A1/en not_active Withdrawn
-
1971
- 1971-04-10 SE SE7112536*A patent/SE383631B/en unknown
- 1971-09-30 SU SU1700834A patent/SU419024A3/en active
- 1971-10-01 CH CH423875A patent/CH587223A5/xx not_active IP Right Cessation
- 1971-10-01 IL IL37830A patent/IL37830A/en unknown
- 1971-10-01 CH CH424175A patent/CH584185A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH424375A patent/CH563341A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH424075A patent/CH583686A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH423975A patent/CH583685A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH424675A patent/CH564516A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH1430971A patent/CH564507A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH424575A patent/CH563342A5/xx not_active IP Right Cessation
- 1971-10-01 CH CH424275A patent/CH583687A5/xx not_active IP Right Cessation
- 1971-10-04 PL PL1971174907A patent/PL84224B1/pl unknown
- 1971-10-04 FI FI2769/71A patent/FI55491C/en active
- 1971-10-04 BG BG20287A patent/BG20100A3/xx unknown
- 1971-10-04 BG BG20288A patent/BG18858A3/xx unknown
- 1971-10-04 NO NO3632/71A patent/NO132835C/no unknown
- 1971-10-04 BE BE773472A patent/BE773472A/en not_active IP Right Cessation
- 1971-10-04 JP JP7778571A patent/JPS5710097B1/ja active Pending
- 1971-10-04 PL PL1971174909A patent/PL84267B1/pl unknown
- 1971-10-04 PL PL1971174903A patent/PL84212B1/pl unknown
- 1971-10-04 PL PL1971174906A patent/PL84225B1/pl unknown
- 1971-10-04 PL PL1971174912A patent/PL84276B1/pl unknown
- 1971-10-04 BG BG20289A patent/BG19134A3/xx unknown
- 1971-10-04 PL PL1971174905A patent/PL84226B1/pl unknown
- 1971-10-04 GB GB4610371A patent/GB1364280A/en not_active Expired
- 1971-10-04 BG BG20290A patent/BG19793A3/xx unknown
- 1971-10-04 ES ES395671A patent/ES395671A1/en not_active Expired
- 1971-10-04 PL PL1971174911A patent/PL84227B1/pl unknown
- 1971-10-04 BG BG20285A patent/BG19133A3/xx unknown
- 1971-10-04 PL PL1971174908A patent/PL84223B1/pl unknown
- 1971-10-04 BG BG20291A patent/BG18859A3/xx unknown
- 1971-10-04 YU YU2505/71A patent/YU35576B/en unknown
- 1971-10-04 PH PH12895A patent/PH9959A/en unknown
- 1971-10-04 PL PL1971150902A patent/PL82037B1/pl unknown
- 1971-10-04 DK DK481671AA patent/DK130958B/en not_active IP Right Cessation
- 1971-10-04 PL PL1971174910A patent/PL84396B1/pl unknown
- 1971-10-04 ZA ZA716643A patent/ZA716643B/en unknown
- 1971-10-04 NL NLAANVRAGE7113581,A patent/NL174249C/en not_active IP Right Cessation
- 1971-10-04 CA CA124,290A patent/CA1008866A/en not_active Expired
- 1971-10-04 BG BG20286A patent/BG18857A3/xx unknown
- 1971-10-04 BG BG18670A patent/BG20338A3/xx unknown
- 1971-10-05 AT AT735573A patent/AT318572B/en not_active IP Right Cessation
- 1971-10-05 RO RO7100073335A patent/RO62357A/en unknown
- 1971-10-05 AT AT734973A patent/AT318566B/en not_active IP Right Cessation
- 1971-10-05 AT AT735173A patent/AT318568B/en not_active IP Right Cessation
- 1971-10-05 RO RO73334A patent/RO62356A/ro unknown
- 1971-10-05 CS CS7034A patent/CS172932B2/cs unknown
- 1971-10-05 RO RO73336A patent/RO62313A/ro unknown
- 1971-10-05 CS CS4618A patent/CS172950B2/cs unknown
- 1971-10-05 RO RO7100073338A patent/RO62358A/en unknown
- 1971-10-05 RO RO68372A patent/RO61540A/ro unknown
- 1971-10-05 AU AU34182/71A patent/AU469119B2/en not_active Expired
- 1971-10-05 AT AT735273A patent/AT318569B/en not_active IP Right Cessation
- 1971-10-05 AT AT735373A patent/AT318570B/en not_active IP Right Cessation
- 1971-10-05 AT AT734773A patent/AT318564B/en not_active IP Right Cessation
- 1971-10-05 RO RO7100073337A patent/RO62267A/en unknown
- 1971-10-05 AT AT859371A patent/AT318561B/en not_active IP Right Cessation
- 1971-10-05 HU HUBO1319A patent/HU163226B/hu unknown
- 1971-10-05 FR FR7135823A patent/FR2110230B1/fr not_active Expired
- 1971-10-05 RO RO7100073339A patent/RO62359A/en unknown
- 1971-10-05 RO RO7100073333A patent/RO62355A/en unknown
- 1971-10-05 IE IE1246/71A patent/IE35693B1/en unknown
- 1971-10-05 AT AT735073A patent/AT318567B/en not_active IP Right Cessation
- 1971-10-05 AT AT734873A patent/AT318565B/en not_active IP Right Cessation
- 1971-10-05 AT AT735473A patent/AT318571B/en not_active IP Right Cessation
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1972
- 1972-02-17 ES ES399871A patent/ES399871A1/en not_active Expired
- 1972-02-17 ES ES399872A patent/ES399872A1/en not_active Expired
- 1972-02-17 ES ES399873A patent/ES399873A1/en not_active Expired
- 1972-02-17 ES ES399874A patent/ES399874A1/en not_active Expired
- 1972-02-17 ES ES399868A patent/ES399868A1/en not_active Expired
- 1972-02-17 ES ES399869A patent/ES399869A1/en not_active Expired
- 1972-02-17 ES ES399870A patent/ES399870A1/en not_active Expired
-
1973
- 1973-02-28 SU SU731888527A patent/SU677649A3/en active
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1975
- 1975-04-03 CH CH414475A patent/CH564515A5/xx not_active IP Right Cessation
-
1976
- 1976-12-06 CH CH1430971A patent/CH587227A5/xx not_active IP Right Cessation
-
1979
- 1979-02-02 YU YU236/79A patent/YU35577B/en unknown
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