ES399110A1 - A procedure for preparing 2-hydroxymethyl-3-hydroxy-6- (1-hydroxy-2-aminoethyl) pyridines. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for preparing 2-hydroxymethyl-3-hydroxy-6- (1-hydroxy-2-aminoethyl) pyridines. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES399110A1 ES399110A1 ES399110A ES399110A ES399110A1 ES 399110 A1 ES399110 A1 ES 399110A1 ES 399110 A ES399110 A ES 399110A ES 399110 A ES399110 A ES 399110A ES 399110 A1 ES399110 A1 ES 399110A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxy
- translation
- preparing
- procedure
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- RBYURGMHFCPCNY-UHFFFAOYSA-N 6-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)pyridin-3-ol Chemical class NCC(O)C1=CC=C(O)C(CO)=N1 RBYURGMHFCPCNY-UHFFFAOYSA-N 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- -1 hydroxy, methoxy Chemical group 0.000 abstract 2
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
A procedure for preparing a compound of the formula: **(See formula)** and the acid addition salts thereof, wherein: R1 is hydrogen, alkyl containing 1 to 5 carbon atoms, cycloalkyl containing 3 to 7 carbon atoms, phenylalkyl or substituted phenylalkyl in which said alkyl group contains from 3 to 5 carbon atoms and the substituent is hydroxy, methoxy, 3,4-dimethoxy or 3,4-methylenedioxy, characterized by removing a protecting group from a compound of the formula: **(See formula)** wherein W is benzyl or substituted benzyl, as defined herein, when Z is hydrogen, or when W and Z taken together form the residue of an acetal or ketal, as defined herein, and where it is desired to form the acid addition salts thereof. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11587871A | 1971-02-16 | 1971-02-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES399110A1 true ES399110A1 (en) | 1974-12-16 |
Family
ID=22363928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES399110A Expired ES399110A1 (en) | 1971-02-16 | 1972-01-22 | A procedure for preparing 2-hydroxymethyl-3-hydroxy-6- (1-hydroxy-2-aminoethyl) pyridines. (Machine-translation by Google Translate, not legally binding) |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5518701B1 (en) |
| AR (2) | AR195962A1 (en) |
| DK (1) | DK137081B (en) |
| ES (1) | ES399110A1 (en) |
| FI (1) | FI52341C (en) |
| IL (1) | IL38588A (en) |
| NO (1) | NO139860C (en) |
| SE (1) | SE377934B (en) |
| SU (2) | SU519130A3 (en) |
| YU (2) | YU35241B (en) |
| ZA (1) | ZA72371B (en) |
-
1972
- 1972-01-19 IL IL38588A patent/IL38588A/en unknown
- 1972-01-19 ZA ZA720371A patent/ZA72371B/en unknown
- 1972-01-22 ES ES399110A patent/ES399110A1/en not_active Expired
- 1972-01-31 FI FI720240A patent/FI52341C/en active
- 1972-02-03 DK DK48072AA patent/DK137081B/en unknown
- 1972-02-03 YU YU252/72A patent/YU35241B/en unknown
- 1972-02-03 AR AR240372A patent/AR195962A1/en active
- 1972-02-03 SU SU1744496A patent/SU519130A3/en active
- 1972-02-03 SE SE7201256A patent/SE377934B/xx unknown
- 1972-02-03 NO NO276/72A patent/NO139860C/en unknown
- 1972-02-04 JP JP1232372A patent/JPS5518701B1/ja active Pending
-
1973
- 1973-09-12 SU SU1962621A patent/SU503518A3/en active
- 1973-10-30 AR AR250765A patent/AR196343A1/en active
-
1978
- 1978-09-26 YU YU2273/78A patent/YU35757B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SU503518A3 (en) | 1976-02-15 |
| DK137081B (en) | 1978-01-16 |
| FI52341C (en) | 1977-08-10 |
| ZA72371B (en) | 1972-09-27 |
| NO139860B (en) | 1979-02-12 |
| IL38588A0 (en) | 1972-03-28 |
| SU519130A3 (en) | 1976-06-25 |
| NO139860C (en) | 1979-05-23 |
| YU35757B (en) | 1981-06-30 |
| IL38588A (en) | 1975-02-10 |
| YU25272A (en) | 1980-04-30 |
| DK137081C (en) | 1978-06-19 |
| AR196343A1 (en) | 1973-12-18 |
| YU227378A (en) | 1980-10-31 |
| YU35241B (en) | 1980-10-31 |
| SE377934B (en) | 1975-08-04 |
| FI52341B (en) | 1977-05-02 |
| JPS5518701B1 (en) | 1980-05-21 |
| AR195962A1 (en) | 1973-11-23 |
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