ES396708A1 - Prostaglandin esters and production thereof - Google Patents

Prostaglandin esters and production thereof

Info

Publication number
ES396708A1
ES396708A1 ES396708A ES396708A ES396708A1 ES 396708 A1 ES396708 A1 ES 396708A1 ES 396708 A ES396708 A ES 396708A ES 396708 A ES396708 A ES 396708A ES 396708 A1 ES396708 A1 ES 396708A1
Authority
ES
Spain
Prior art keywords
production
prostaglandin
reacting
prostaglandin esters
amine salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES396708A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Publication of ES396708A1 publication Critical patent/ES396708A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

Abstract

A process for producing prostaglandin esters characterized by converting a prostaglandin to its tertiary amine salt, reacting said amine salt with a pivaloyl halide to form a mixed acid anhydride, and then reacting said anhydride with an alcohol or phenol. (Machine-translation by Google Translate, not legally binding)
ES396708A 1970-11-10 1971-11-05 Prostaglandin esters and production thereof Expired ES396708A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9891970A JPS4920766B1 (en) 1970-11-10 1970-11-10

Publications (1)

Publication Number Publication Date
ES396708A1 true ES396708A1 (en) 1975-04-16

Family

ID=14232524

Family Applications (1)

Application Number Title Priority Date Filing Date
ES396708A Expired ES396708A1 (en) 1970-11-10 1971-11-05 Prostaglandin esters and production thereof

Country Status (15)

Country Link
JP (1) JPS4920766B1 (en)
AR (1) AR193625A1 (en)
BE (1) BE775106A (en)
CA (1) CA951314A (en)
CH (1) CH559716A5 (en)
DD (1) DD95372A5 (en)
DE (1) DE2155546A1 (en)
DK (1) DK128733B (en)
ES (1) ES396708A1 (en)
FR (1) FR2113883B1 (en)
GB (1) GB1362956A (en)
HU (1) HU162848B (en)
NL (1) NL7115393A (en)
NO (1) NO133325C (en)
SU (1) SU433670A3 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4163108A (en) * 1967-02-16 1979-07-31 Lever Brothers Company Prostaglandins
JPS4942648A (en) * 1972-08-24 1974-04-22
US3984424A (en) * 1972-11-08 1976-10-05 Pfizer Inc. P-biphenyl esters of 15-substituted-ω-pentanorprostaglandins
US3989736A (en) * 1973-01-08 1976-11-02 Pfizer Inc. Prostaglandin 5-indanyl esters
US3968140A (en) * 1974-01-08 1976-07-06 The Upjohn Company Substituted anilide esters of PGE1
US3890372A (en) * 1974-01-08 1975-06-17 Upjohn Co Amino substituted phenyl and naphthyl esters of PGF{HD 2{301 {B - type compounds
US3931281A (en) * 1974-01-08 1976-01-06 The Upjohn Company Substituted anilide ester of PGA2
US3959319A (en) * 1974-01-08 1976-05-25 The Upjohn Company Phenyl and naphthyl esters of PGF2 α type prostaglandins
US3969464A (en) * 1974-01-08 1976-07-13 The Upjohn Company Polycyclic aromatic esters of PGA1
US4013693A (en) * 1974-01-08 1977-03-22 The Upjohn Company Substituted phenyl esters of PGA1
US3988355A (en) * 1974-01-08 1976-10-26 The Upjohn Company Substituted phenyl and naphthyl esters of PGE1
US4013707A (en) * 1974-01-08 1977-03-22 The Upjohn Company Substituted phenyl esters of PGA1
US3932486A (en) * 1974-01-08 1976-01-13 The Upjohn Company Substituted tolyl esters of PGA2
US3962289A (en) * 1974-01-08 1976-06-08 The Upjohn Company Esters of PGA2 and p-tritylphenol
US3948970A (en) * 1974-01-08 1976-04-06 The Upjohn Company Substituted tolyl esters of PGA1
US3987067A (en) * 1974-01-08 1976-10-19 The Upjohn Company Substituted aromatic esters of PGF2.sub.α
US3931285A (en) * 1974-01-08 1976-01-06 The Upjohn Company Substituted tolyl esters of PGE1
US3998869A (en) * 1974-11-14 1976-12-21 The Upjohn Company Substituted anilide esters of 16-substituted PGE2
US4042606A (en) * 1974-12-12 1977-08-16 The Upjohn Company Substituted phenyl esters of PGA2
US4058551A (en) * 1974-12-12 1977-11-15 The Upjohn Company Substituted phenyl esters of PGA2
JPS5420344U (en) * 1977-07-13 1979-02-09
ES2213504T1 (en) 1988-09-06 2004-09-01 Pfizer Health Ab PROSTAGLANDIN DERIVATIVES FOR THE TREATMENT OF GLAUCOMA OR OCULAR HYPERTENSION.
AU2001284753B2 (en) 2000-08-07 2006-10-26 Vanderbilt University Detection of COX-2 activity and anandamide metabolites
US7314709B2 (en) 2002-08-06 2008-01-01 Vanderbilt University Compositions and methods for detecting and quantifying COX-2 activity by lipoamino acid metabolism
EP2781505A1 (en) * 2006-10-02 2014-09-24 Techfields Biochem Co. Ltd Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin penetration rates
JP5925158B2 (en) * 2013-06-04 2016-05-25 テックフィールズ バイオケム カンパニー リミテッド Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin permeability
JP6030168B2 (en) * 2015-03-09 2016-11-24 テックフィールズ バイオケム カンパニー リミテッド Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin permeability
JP6306067B2 (en) * 2016-01-08 2018-04-04 テックフィールズ バイオケム カンパニー リミテッド Positively charged water-soluble prodrugs of prostaglandins and related compounds with very high skin permeability
CN109400513B (en) * 2018-11-26 2020-06-09 武汉嘉诺康医药技术有限公司 Method for purifying carboprost

Also Published As

Publication number Publication date
CA951314A (en) 1974-07-16
SU433670A3 (en) 1974-06-25
CH559716A5 (en) 1975-03-14
JPS4920766B1 (en) 1974-05-27
NO133325C (en) 1976-04-12
HU162848B (en) 1973-04-28
NL7115393A (en) 1972-05-15
BE775106A (en) 1972-03-01
AR193625A1 (en) 1973-05-11
FR2113883B1 (en) 1975-08-01
NO133325B (en) 1976-01-05
DD95372A5 (en) 1973-02-05
DE2155546A1 (en) 1972-05-18
GB1362956A (en) 1974-08-07
FR2113883A1 (en) 1972-06-30
DK128733B (en) 1974-06-24

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