ES396293A1 - Preparation of 1-alkyl-2-aminomethyl-pyrrolidines - Google Patents
Preparation of 1-alkyl-2-aminomethyl-pyrrolidinesInfo
- Publication number
- ES396293A1 ES396293A1 ES396293A ES396293A ES396293A1 ES 396293 A1 ES396293 A1 ES 396293A1 ES 396293 A ES396293 A ES 396293A ES 396293 A ES396293 A ES 396293A ES 396293 A1 ES396293 A1 ES 396293A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- aminomethyl
- preparation
- pyrrolidines
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
Abstract
Procedure for the preparation of 1-alkyl-2-aminomethylpyrralidines, characterized in that a 1-alkyl-2-pyrrolidone is reacted with phosgene in a solvent medium at a temperature between -5ºC and + 10ºC, then it is added to the obtained product, whose temperature has been decreased between 0ºC and 20ºC, an alkaline alcoholate, and then nitromethane is added to the mixture brought back to room temperature, and finally the nitromethylene grouping obtained is reduced to aminomethyl grouping. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1662870A CH532035A (en) | 1970-11-10 | 1970-11-10 | New process for the preparation of 1-alkyl-2-amino-methylpyrrolidines |
Publications (1)
Publication Number | Publication Date |
---|---|
ES396293A1 true ES396293A1 (en) | 1974-05-01 |
Family
ID=4418871
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES396293A Expired ES396293A1 (en) | 1970-11-10 | 1971-10-22 | Preparation of 1-alkyl-2-aminomethyl-pyrrolidines |
Country Status (27)
Country | Link |
---|---|
AT (1) | AT311952B (en) |
AU (1) | AU464960B2 (en) |
BE (1) | BE773979A (en) |
BG (1) | BG21605A3 (en) |
CA (1) | CA940533A (en) |
CH (1) | CH532035A (en) |
CS (1) | CS186206B2 (en) |
DE (1) | DE2152371A1 (en) |
DK (1) | DK145573C (en) |
ES (1) | ES396293A1 (en) |
FI (1) | FI54471C (en) |
FR (1) | FR2111371A5 (en) |
GB (1) | GB1374818A (en) |
HU (1) | HU162787B (en) |
IE (1) | IE35775B1 (en) |
IL (1) | IL37994A (en) |
IT (1) | IT1043845B (en) |
LU (1) | LU64227A1 (en) |
MC (1) | MC896A1 (en) |
NL (1) | NL7114901A (en) |
OA (1) | OA03823A (en) |
PH (1) | PH12022A (en) |
PL (1) | PL81412B1 (en) |
SE (1) | SE376415B (en) |
YU (1) | YU34672B (en) |
ZA (1) | ZA716998B (en) |
ZM (1) | ZM15171A1 (en) |
-
1970
- 1970-11-10 CH CH1662870A patent/CH532035A/en not_active IP Right Cessation
-
1971
- 1971-10-14 FR FR7136940A patent/FR2111371A5/fr not_active Expired
- 1971-10-15 BE BE773979A patent/BE773979A/en not_active IP Right Cessation
- 1971-10-19 ZA ZA716998A patent/ZA716998B/en unknown
- 1971-10-20 AU AU34790/71A patent/AU464960B2/en not_active Expired
- 1971-10-21 DE DE19712152371 patent/DE2152371A1/en active Pending
- 1971-10-22 ES ES396293A patent/ES396293A1/en not_active Expired
- 1971-10-22 IL IL37994A patent/IL37994A/en unknown
- 1971-10-26 MC MC953A patent/MC896A1/en unknown
- 1971-10-26 CA CA126,128A patent/CA940533A/en not_active Expired
- 1971-10-26 BG BG18861A patent/BG21605A3/xx unknown
- 1971-10-26 IE IE1354/71A patent/IE35775B1/en unknown
- 1971-10-27 ZM ZM151/71A patent/ZM15171A1/en unknown
- 1971-10-28 NL NL7114901A patent/NL7114901A/xx unknown
- 1971-10-29 IT IT30520/71A patent/IT1043845B/en active
- 1971-11-04 CS CS7100007753A patent/CS186206B2/en unknown
- 1971-11-04 GB GB5122571A patent/GB1374818A/en not_active Expired
- 1971-11-05 OA OA54406A patent/OA03823A/en unknown
- 1971-11-08 FI FI3193/71A patent/FI54471C/en active
- 1971-11-08 PL PL1971151433A patent/PL81412B1/pl unknown
- 1971-11-08 LU LU64227D patent/LU64227A1/xx unknown
- 1971-11-09 SE SE7114274A patent/SE376415B/xx unknown
- 1971-11-09 HU HUFA897A patent/HU162787B/hu unknown
- 1971-11-09 DK DK548871A patent/DK145573C/en not_active IP Right Cessation
- 1971-11-09 YU YU2823/71A patent/YU34672B/en unknown
- 1971-11-10 AT AT969071A patent/AT311952B/en not_active IP Right Cessation
- 1971-11-10 PH PH13000A patent/PH12022A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BG21605A3 (en) | 1976-07-20 |
CS186206B2 (en) | 1978-11-30 |
AT311952B (en) | 1973-12-10 |
YU282371A (en) | 1979-07-10 |
IL37994A0 (en) | 1971-12-29 |
IT1043845B (en) | 1980-02-29 |
HU162787B (en) | 1973-04-28 |
ZA716998B (en) | 1972-07-26 |
MC896A1 (en) | 1972-06-22 |
DK145573B (en) | 1982-12-13 |
YU34672B (en) | 1979-12-31 |
DK145573C (en) | 1983-05-30 |
OA03823A (en) | 1971-12-24 |
DE2152371A1 (en) | 1972-06-22 |
BE773979A (en) | 1972-04-17 |
NL7114901A (en) | 1972-05-15 |
CA940533A (en) | 1974-01-22 |
PH12022A (en) | 1978-10-06 |
GB1374818A (en) | 1974-11-20 |
IL37994A (en) | 1974-10-22 |
SE376415B (en) | 1975-05-26 |
FI54471C (en) | 1978-12-11 |
FR2111371A5 (en) | 1972-06-02 |
LU64227A1 (en) | 1972-05-29 |
ZM15171A1 (en) | 1972-07-21 |
AU464960B2 (en) | 1975-09-11 |
CH532035A (en) | 1972-12-31 |
IE35775B1 (en) | 1976-05-12 |
FI54471B (en) | 1978-08-31 |
PL81412B1 (en) | 1975-08-30 |
AU3479071A (en) | 1973-05-03 |
IE35775L (en) | 1972-05-10 |
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