ES384344A1 - Propadienyl steroids - Google Patents
Propadienyl steroidsInfo
- Publication number
- ES384344A1 ES384344A1 ES384344A ES384344A ES384344A1 ES 384344 A1 ES384344 A1 ES 384344A1 ES 384344 A ES384344 A ES 384344A ES 384344 A ES384344 A ES 384344A ES 384344 A1 ES384344 A1 ES 384344A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- hydroxy
- ether
- propadienyl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
A method of synthesis of C-17α propadienyl alkyl substituted steroids, which consists of reacting a 17α- (3-substituted propinyl) steroid, where the substituent is halogen, hydroxy or its conventionally hydrolyzable ester or ether, with a lithium dialkyl reagent and copper, thus obtaining the corresponding 17α-propadienyl alkyl substituted represented by the formulas: **(See formula)** where R1 is lower alkyl; R2 and R3 are each hydrogen or lower alkyl; R4 is hydrogen or alkyl of 1 to 3 carbon atoms, inclusive; R5 is hydroxy or its conventionally hydrolyzable ester or ether; R6 is a keto group or the group R8-H: wherein R8 is hydrogen, hydroxy or its conventionally hydrolyzable ester or ether and R7 is hydrogen or methyl. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4556670A | 1970-06-11 | 1970-06-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES384344A1 true ES384344A1 (en) | 1973-05-01 |
Family
ID=21938650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES384344A Expired ES384344A1 (en) | 1970-06-11 | 1970-10-08 | Propadienyl steroids |
Country Status (9)
| Country | Link |
|---|---|
| BE (1) | BE755860A (en) |
| CA (1) | CA935814A (en) |
| CH (1) | CH577529A5 (en) |
| DE (1) | DE2043028A1 (en) |
| ES (1) | ES384344A1 (en) |
| FR (1) | FR2094176B1 (en) |
| GB (1) | GB1316847A (en) |
| NL (1) | NL7011445A (en) |
| ZA (1) | ZA704614B (en) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3875188A (en) * | 1968-04-10 | 1975-04-01 | Eugene E Galantay | 17-Beta-alpha-lower alkyl allene-substituted steroids |
| IL34227A (en) * | 1969-04-18 | 1974-09-10 | Syntex Corp | Process for the preparation of 17alpha-propadienyl steroids and new 6,6-difluoro-17alpha-propadienyl-17beta-hydroxy-delta4 estrenes and androstenes |
-
0
- BE BE755860D patent/BE755860A/en unknown
-
1970
- 1970-07-06 ZA ZA704614A patent/ZA704614B/en unknown
- 1970-08-03 NL NL7011445A patent/NL7011445A/xx unknown
- 1970-08-18 GB GB3975170A patent/GB1316847A/en not_active Expired
- 1970-08-27 CH CH1286470A patent/CH577529A5/xx not_active IP Right Cessation
- 1970-08-31 DE DE19702043028 patent/DE2043028A1/en active Pending
- 1970-10-08 ES ES384344A patent/ES384344A1/en not_active Expired
- 1970-11-06 FR FR7040062A patent/FR2094176B1/fr not_active Expired
- 1970-12-02 CA CA099624A patent/CA935814A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA935814A (en) | 1973-10-23 |
| DE2043028A1 (en) | 1971-12-16 |
| CH577529A5 (en) | 1976-07-15 |
| BE755860A (en) | 1971-02-15 |
| GB1316847A (en) | 1973-05-16 |
| FR2094176B1 (en) | 1974-08-23 |
| NL7011445A (en) | 1971-12-14 |
| FR2094176A1 (en) | 1972-02-04 |
| ZA704614B (en) | 1972-02-23 |
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