ES373377A1 - Procedimiento para la obtencion de quinalozinonas. - Google Patents
Procedimiento para la obtencion de quinalozinonas.Info
- Publication number
- ES373377A1 ES373377A1 ES373377A ES373377A ES373377A1 ES 373377 A1 ES373377 A1 ES 373377A1 ES 373377 A ES373377 A ES 373377A ES 373377 A ES373377 A ES 373377A ES 373377 A1 ES373377 A1 ES 373377A1
- Authority
- ES
- Spain
- Prior art keywords
- quinazolinones
- aryl
- substituted
- pharmaceutical agents
- quinazolinone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US00775201A US3723432A (en) | 1968-11-12 | 1968-11-12 | 1-substituted-4-aryl-2(1h)-quinazolinones and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES373377A1 true ES373377A1 (es) | 1972-05-16 |
Family
ID=25103642
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES373377A Expired ES373377A1 (es) | 1968-11-12 | 1969-11-10 | Procedimiento para la obtencion de quinalozinonas. |
Country Status (19)
Country | Link |
---|---|
US (2) | US3723432A (es) |
AT (4) | AT310169B (es) |
BE (1) | BE741529A (es) |
BG (10) | BG16042A3 (es) |
BR (1) | BR6914095D0 (es) |
CH (1) | CH521972A (es) |
DE (1) | DE1956384C3 (es) |
DK (1) | DK129347B (es) |
ES (1) | ES373377A1 (es) |
FR (1) | FR2024830B1 (es) |
GB (1) | GB1282612A (es) |
IE (1) | IE33933B1 (es) |
IL (1) | IL33348A (es) |
NL (1) | NL6916514A (es) |
NO (1) | NO124032B (es) |
OA (1) | OA03829A (es) |
PL (1) | PL72695B1 (es) |
SE (2) | SE376917B (es) |
ZA (1) | ZA697910B (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3923803A (en) * | 1968-07-18 | 1975-12-02 | Sumitomo Chemical Co | 2(1H)-Quinozalinones and process therefor |
US3642791A (en) * | 1969-08-13 | 1972-02-15 | Sandoz Ag | Morpholino-1-substituted-2(1h)-quinazolinones |
US4208343A (en) * | 1970-10-30 | 1980-06-17 | Westinghouse Electric Corp. | 2,4 Diamino benzonitrile |
BE785937A (fr) * | 1971-07-08 | 1973-01-08 | Sandoz Sa | Nouveaux derives de la quinazoline, leur preparation et leur application comme medicaments |
US3937705A (en) * | 1972-03-09 | 1976-02-10 | Sandoz, Inc. | 1-isopropyl-7-methyl-4-(p-fluorophenyl)-2(1h)-quinazolinone |
US4071516A (en) * | 1976-08-20 | 1978-01-31 | Sandoz, Inc. | 4-(Acyloxyphenyl)-quinazolin-2(1H)-ones |
US4064246A (en) * | 1976-10-12 | 1977-12-20 | Sandoz, Inc. | Hydroxymethyl-substituted-2(1H)-quinazolinones |
US4160092A (en) * | 1977-06-16 | 1979-07-03 | E. I. Du Pont De Nemours And Company | Quinazolinone oxides and their use as intermediates for pharmaceutical agents |
US4224328A (en) * | 1979-04-11 | 1980-09-23 | Sandoz, Inc. | Methods with 1-substituted-4-aryl-quinazolin-2(1H)-ones and thiones and pyrido[2,3-d]pyrimidin-2-ones as platelet aggregation inhibitors |
CH645362A5 (de) * | 1979-07-05 | 1984-09-28 | Sandoz Ag | Verfahren zur herstellung von 4-phenyl-2(1h)-chinazolinonen. |
FR2676042B1 (fr) * | 1991-05-02 | 1993-07-23 | Commissariat Energie Atomique | Procede de preparation d'un borohydrure de metal alcalin tel que le borohydrure de lithium. |
US6545004B1 (en) | 1999-10-27 | 2003-04-08 | Cytokinetics, Inc. | Methods and compositions utilizing quinazolinones |
US7230000B1 (en) | 1999-10-27 | 2007-06-12 | Cytokinetics, Incorporated | Methods and compositions utilizing quinazolinones |
AR038658A1 (es) | 2001-06-15 | 2005-01-26 | Novartis Ag | Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento |
AU2002346471A1 (en) * | 2001-11-20 | 2003-06-10 | Cytokinetics, Inc. | Process for the racemization of chiral quinazolinones |
WO2003070701A2 (en) * | 2002-02-15 | 2003-08-28 | Cytokinetics, Inc. | Syntheses of quinazolinones |
WO2003097053A1 (en) | 2002-05-09 | 2003-11-27 | Cytokinetics, Inc. | Compounds, compositions, and methods |
CN100491358C (zh) * | 2002-05-09 | 2009-05-27 | 赛特凯恩蒂克公司 | 嘧啶酮类化合物、组合物及方法 |
US7038048B2 (en) * | 2002-05-23 | 2006-05-02 | Cytokinetics, Inc. | 3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use |
WO2003106426A1 (en) * | 2002-06-14 | 2003-12-24 | Cytokinetics, Inc. | Compounds, compositions, and methods |
JP2006501201A (ja) * | 2002-07-23 | 2006-01-12 | サイトキネティクス・インコーポレーテッド | 化合物、組成物および方法 |
US20040048853A1 (en) * | 2002-08-21 | 2004-03-11 | Gustave Bergnes | Compounds, compositions, and methods |
WO2004034972A2 (en) * | 2002-09-30 | 2004-04-29 | Cytokinetics, Inc. | Compounds, compositions, and methods |
GB0230015D0 (en) * | 2002-12-23 | 2003-01-29 | Novartis Ag | Organic compounds |
US7439241B2 (en) * | 2003-05-27 | 2008-10-21 | Galderma Laboratories, Inc. | Compounds, formulations, and methods for treating or preventing rosacea |
US8410102B2 (en) | 2003-05-27 | 2013-04-02 | Galderma Laboratories Inc. | Methods and compositions for treating or preventing erythema |
EP1682534A2 (en) * | 2003-11-03 | 2006-07-26 | Cytokinetics, Inc. | Pyrimidin-4-one compounds, compositions, and methods |
WO2005046588A2 (en) * | 2003-11-07 | 2005-05-26 | Cytokinetics, Inc. | Compounds, compositions, and methods |
WO2005061460A1 (en) * | 2003-12-08 | 2005-07-07 | Cytokinetics, Inc. | Compounds, compositions, and methods |
JP2010530885A (ja) * | 2007-06-22 | 2010-09-16 | アークル インコーポレイテッド | キナゾリノン化合物およびその使用方法 |
US8058469B2 (en) * | 2008-11-03 | 2011-11-15 | Sabic Innovative Plastics Ip B.V. | Method for making carbamates, ureas and isocyanates |
EP2329849B1 (en) | 2009-11-18 | 2015-04-29 | Galderma Research & Development | Combination of alpha-2 adrenergic receptor agonist and non-steroidal anti-inflammatory agent for treating or preventing an inflammatory skin disorder |
US8394800B2 (en) | 2009-11-19 | 2013-03-12 | Galderma Laboratories, L.P. | Method for treating psoriasis |
JP5747392B2 (ja) | 2010-03-26 | 2015-07-15 | ガルデルマ・リサーチ・アンド・デヴェロップメント | 毛細血管拡張症の安全かつ有効な治療のための改善された方法および組成物 |
HUE033143T2 (en) | 2010-03-26 | 2017-11-28 | Galderma Res & Dev | Preparations containing brimonidine for the treatment of erythema |
US8053427B1 (en) | 2010-10-21 | 2011-11-08 | Galderma R&D SNC | Brimonidine gel composition |
RU2571277C2 (ru) | 2010-10-21 | 2015-12-20 | Галдерма С.А. | Композиции геля с бримонидином и способы применения |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3452041A (en) * | 1965-05-19 | 1969-06-24 | American Home Prod | Hydantoin compounds and methods of preparation |
-
1968
- 1968-11-12 US US00775201A patent/US3723432A/en not_active Expired - Lifetime
- 1968-11-12 BG BG015055A patent/BG16042A3/bg unknown
-
1969
- 1969-10-31 GB GB53620/69A patent/GB1282612A/en not_active Expired
- 1969-10-31 CH CH1624569A patent/CH521972A/de not_active IP Right Cessation
- 1969-11-03 NL NL6916514A patent/NL6916514A/xx not_active Application Discontinuation
- 1969-11-07 FR FR696938404A patent/FR2024830B1/fr not_active Expired
- 1969-11-10 AT AT1053269A patent/AT310169B/de not_active IP Right Cessation
- 1969-11-10 ES ES373377A patent/ES373377A1/es not_active Expired
- 1969-11-10 AT AT993571A patent/AT310176B/de not_active IP Right Cessation
- 1969-11-10 OA OA53783A patent/OA03829A/xx unknown
- 1969-11-10 BG BG013325A patent/BG16188A3/bg unknown
- 1969-11-10 BG BG014696A patent/BG16040A3/bg unknown
- 1969-11-10 AT AT993071A patent/AT319949B/de not_active IP Right Cessation
- 1969-11-10 AT AT993271A patent/AT319950B/de not_active IP Right Cessation
- 1969-11-10 BG BG014695A patent/BG16039A3/bg unknown
- 1969-11-10 BG BG014692A patent/BG16036A3/bg unknown
- 1969-11-10 BE BE741529A patent/BE741529A/xx unknown
- 1969-11-10 BG BG014694A patent/BG16038A3/bg unknown
- 1969-11-10 BG BG015469A patent/BG16043A3/bg unknown
- 1969-11-10 IE IE1526/69A patent/IE33933B1/xx unknown
- 1969-11-10 BG BG014693A patent/BG16037A3/bg unknown
- 1969-11-10 NO NO4445/69A patent/NO124032B/no unknown
- 1969-11-10 DE DE1956384A patent/DE1956384C3/de not_active Expired
- 1969-11-11 BR BR214095/69A patent/BR6914095D0/pt unknown
- 1969-11-11 IL IL33348A patent/IL33348A/xx unknown
- 1969-11-11 SE SE7213438A patent/SE376917B/xx unknown
- 1969-11-11 DK DK597169AA patent/DK129347B/da unknown
- 1969-11-11 SE SE6915448A patent/SE374920B/xx unknown
- 1969-11-12 PL PL1969136872A patent/PL72695B1/pl unknown
- 1969-11-12 ZA ZA697910A patent/ZA697910B/xx unknown
-
1970
- 1970-05-16 BG BG014697A patent/BG16041A3/bg unknown
- 1970-08-13 BG BG015468A patent/BG15573A3/bg unknown
-
1972
- 1972-12-08 US US313531A patent/US3925548A/en not_active Expired - Lifetime
Also Published As
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