ES351661A1 - Procedimiento de fabricacion de nuevas 18-metil-19-nor-17- alfa-hidroxiprogesteronas y de sus 3-enol-17-di-0-17-mono- esteres. - Google Patents

Procedimiento de fabricacion de nuevas 18-metil-19-nor-17- alfa-hidroxiprogesteronas y de sus 3-enol-17-di-0-17-mono- esteres.

Info

Publication number: ES351661A1
Authority: ES; Spain
Prior art keywords: methyl; alpha; enol; diol; ether
Prior art date: 1967-05-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES351661A

Other languages

English (en)

Spanish (es)

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bayer Pharma AG

Original Assignee

Schering AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1967-05-05

Filing date

1968-03-15

Publication date

1969-06-01

1968-03-15 Application filed by Schering AG filed Critical Schering AG

1969-06-01 Publication of ES351661A1 publication Critical patent/ES351661A1/es

Status Expired legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 2
229960002899 hydroxyprogesterone Drugs 0.000 abstract 2
CRMOMCHYBNOFIV-BDXSIMOUSA-N 16-estratetraen-3-ol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C=CC4)[C@@H]4[C@@H]3CCC2=C1 CRMOMCHYBNOFIV-BDXSIMOUSA-N 0.000 abstract 1
-1 20,20 - Ethylenedioxy Chemical group 0.000 abstract 1
235000018185 Betula X alpestris Nutrition 0.000 abstract 1
235000018212 Betula X uliginosa Nutrition 0.000 abstract 1
230000000887 hydrating effect Effects 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
150000002730 mercury Chemical class 0.000 abstract 1
230000001590 oxidative effect Effects 0.000 abstract 1
238000010561 standard procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)

ES351661A 1967-05-05 1968-03-15 Procedimiento de fabricacion de nuevas 18-metil-19-nor-17- alfa-hidroxiprogesteronas y de sus 3-enol-17-di-0-17-mono- esteres. Expired ES351661A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DESC040657		1967-05-05

Publications (1)

Publication Number	Publication Date
ES351661A1 true ES351661A1 (es)	1969-06-01

Family

ID=7435799

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES351661A Expired ES351661A1 (es)	1967-05-05	1968-03-15	Procedimiento de fabricacion de nuevas 18-metil-19-nor-17- alfa-hidroxiprogesteronas y de sus 3-enol-17-di-0-17-mono- esteres.

Country Status (13)

Country	Link
AT (1)	AT279819B (da)
BE (1)	BE714593A (da)
CA (1)	CA923891A (da)
CH (2)	CH581150A5 (da)
CS (1)	CS150217B2 (da)
DK (1)	DK119976B (da)
ES (1)	ES351661A1 (da)
FI (1)	FI45175C (da)
FR (2)	FR1581520A (da)
GB (1)	GB1226356A (da)
NL (1)	NL160276C (da)
NO (1)	NO127194B (da)
SE (1)	SE335856B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5655400A (en) *	1979-10-12	1981-05-15	Mitsubishi Chem Ind Ltd	Improved preparation process of 4,6-dien-3-one steroid
HU216828B (hu) *	1995-12-22	1999-09-28	Richter Gedeon Vegyészeti Gyár Rt.	Szteránvázas vegyületek, eljárás ezek előállítására, az ezeket tartalmazó gyógyászati készítmények és intermedierjeik
HUP0301332A3 (en) *	2003-05-14	2006-04-28	Richter Gedeon Vegyeszet	New mono-and bismethylene steroid derivatives and process for their synthesis and pharmaceutical compositions containing them

1968
- 1968-02-29 CH CH296668A patent/CH581150A5/xx not_active IP Right Cessation
- 1968-03-06 FI FI680607A patent/FI45175C/fi active
- 1968-03-12 AT AT244868A patent/AT279819B/de not_active IP Right Cessation
- 1968-03-12 CS CS1920A patent/CS150217B2/cs unknown
- 1968-03-15 ES ES351661A patent/ES351661A1/es not_active Expired
- 1968-03-19 DK DK116668AA patent/DK119976B/da unknown
- 1968-03-26 SE SE04008/68A patent/SE335856B/xx unknown
- 1968-04-02 GB GB1226356D patent/GB1226356A/en not_active Expired
- 1968-05-03 NL NL6806348.A patent/NL160276C/xx not_active IP Right Cessation
- 1968-05-03 CA CA019125A patent/CA923891A/en not_active Expired
- 1968-05-03 FR FR1581520D patent/FR1581520A/fr not_active Expired
- 1968-05-03 BE BE714593D patent/BE714593A/xx not_active IP Right Cessation
- 1968-05-03 NO NO01721/68A patent/NO127194B/no unknown
- 1968-08-01 FR FR161486A patent/FR8084M/fr not_active Expired
1974
- 1974-10-07 CH CH296668A patent/CH563408A5/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE1643020A1 (de)	1971-04-15
CA923891A (en)	1973-04-03
FR1581520A (da)	1969-09-19
BE714593A (da)	1968-11-04
CH581150A5 (da)	1976-10-29
NO127194B (da)	1973-05-21
NL6806348A (da)	1968-11-06
NL160276B (nl)	1979-05-15
FI45175B (da)	1971-12-31
CS150217B2 (da)	1973-09-04
FI45175C (fi)	1972-04-10
GB1226356A (da)	1971-03-24
FR8084M (da)	1970-07-20
CH563408A5 (da)	1975-06-30
NL160276C (nl)	1979-10-15
AT279819B (de)	1970-03-25
SE335856B (da)	1971-06-14
DK119976B (da)	1971-03-22

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