ES341311A1 - Un procedimiento para la preparacion de derivados de benzo-diacepina. - Google Patents

Un procedimiento para la preparacion de derivados de benzo-diacepina.

Info

Publication number
ES341311A1
ES341311A1 ES341311A ES341311A ES341311A1 ES 341311 A1 ES341311 A1 ES 341311A1 ES 341311 A ES341311 A ES 341311A ES 341311 A ES341311 A ES 341311A ES 341311 A1 ES341311 A1 ES 341311A1
Authority
ES
Spain
Prior art keywords
benzodiazepines
forming
dehydration process
acid addition
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES341311A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES341311A1 publication Critical patent/ES341311A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES341311A 1966-06-03 1967-06-02 Un procedimiento para la preparacion de derivados de benzo-diacepina. Expired ES341311A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55496466A 1966-06-03 1966-06-03

Publications (1)

Publication Number Publication Date
ES341311A1 true ES341311A1 (es) 1968-10-16

Family

ID=24215433

Family Applications (1)

Application Number Title Priority Date Filing Date
ES341311A Expired ES341311A1 (es) 1966-06-03 1967-06-02 Un procedimiento para la preparacion de derivados de benzo-diacepina.

Country Status (17)

Country Link
US (1) US3501460A (es)
BE (1) BE699047A (es)
CH (1) CH483434A (es)
CY (1) CY507A (es)
DE (1) DE1695188C3 (es)
DK (1) DK116288B (es)
ES (1) ES341311A1 (es)
FI (1) FI47488C (es)
GB (1) GB1153101A (es)
GR (1) GR36820B (es)
IL (1) IL27980A (es)
MY (2) MY6900417A (es)
NL (1) NL6707722A (es)
NO (2) NO136976C (es)
OA (1) OA02443A (es)
SE (2) SE357963B (es)
YU (1) YU32366B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723414A (en) * 1970-02-13 1973-03-27 Schering Corp 1-polyfluoroalkyl benzodiazepines
DE2221558C2 (de) * 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
IL27980A (en) 1971-10-20
NO137937C (no) 1978-05-24
GB1153101A (en) 1969-05-21
DE1695188A1 (de) 1971-04-08
DE1695188C3 (de) 1980-12-11
NO137937B (no) 1978-02-13
US3501460A (en) 1970-03-17
FI47488B (es) 1973-08-31
GR36820B (el) 1969-03-12
CH483434A (de) 1969-12-31
FI47488C (fi) 1973-12-10
DE1695188B2 (de) 1980-04-17
NO136976C (no) 1977-12-07
CY507A (en) 1969-11-19
YU32366B (en) 1974-10-31
DK116288B (da) 1969-12-29
NO136976B (no) 1977-08-29
NL6707722A (es) 1967-12-04
MY6900417A (en) 1969-12-31
BE699047A (es) 1967-11-27
OA02443A (fr) 1970-05-05
SE321683B (es) 1970-03-16
SE357963B (es) 1973-07-16
YU109867A (en) 1974-04-30
MY7000025A (en) 1970-12-31

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