ES310125A1 - Procedure for the preparation of fenantrenic derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of fenantrenic derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES310125A1
ES310125A1 ES0310125A ES310125A ES310125A1 ES 310125 A1 ES310125 A1 ES 310125A1 ES 0310125 A ES0310125 A ES 0310125A ES 310125 A ES310125 A ES 310125A ES 310125 A1 ES310125 A1 ES 310125A1
Authority
ES
Spain
Prior art keywords
radical
carbon atoms
group
translation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0310125A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES310125A1 publication Critical patent/ES310125A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for the preparation of phenanthrene derivatives, of the general formula ** (See formula) ** where R represents hydrogen, a lower, saturated or unsaturated aliphatic hydrocarbon group, or an acyl group and Z represents a cycloalkyl group unsubstituted or substituted by lower alkyl, with 3 to 6 carbon atoms in the ring, except that when Z is a cyclopropyl group, the total number of carbon atoms in the radical is 4. less; when Z is a cyclobutyl group, the total number of carbon atoms in the radical is at least 4; and when Z is a cyclobutyl group, the total number of carbon atoms in the radical is at least 5, and the salts of these compounds, characterized in that it consists of replacing the hydrogen atom that is attached to the nitrogen atom of a phenanthrene compound of the formula ** (See formula) ** for the radical -CH2-Z III and, if desired, in converting a compound thus obtained into an ether, an ester and/or a salt. (Machine-translation by Google Translate, not legally binding)
ES0310125A 1964-03-05 1965-03-04 Procedure for the preparation of fenantrenic derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES310125A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH283764A CH446370A (en) 1964-03-05 1964-03-05 Process for the preparation of phenanthrene derivatives

Publications (1)

Publication Number Publication Date
ES310125A1 true ES310125A1 (en) 1965-12-01

Family

ID=4242707

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0310125A Expired ES310125A1 (en) 1964-03-05 1965-03-04 Procedure for the preparation of fenantrenic derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
BE (1) BE660533A (en)
CH (1) CH446370A (en)
DK (1) DK107485C (en)
ES (1) ES310125A1 (en)
FR (2) FR1428671A (en)
GB (1) GB1043859A (en)
NL (1) NL6502391A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2538075A1 (en) 1975-08-27 1977-03-17 Boehringer Sohn Ingelheim N-TETRAHYDROFURFURYL NOROXYMORPHONES, THEIR ACID ADDITIONAL SALTS, THE MEDICINAL PRODUCTS AND THE METHOD FOR THEIR MANUFACTURING
EP0184041A1 (en) * 1984-11-13 1986-06-11 Miles Inc. 6-Methylene morphinan purification technique
US5260286A (en) * 1992-10-16 1993-11-09 Japan Tobacco, Inc. 2-piperidinecarboxylic acid derivatives useful as NMDA receptor antagonists

Also Published As

Publication number Publication date
DK107485C (en) 1967-06-05
NL6502391A (en) 1965-09-06
BE660533A (en) 1965-09-03
GB1043859A (en) 1966-09-28
FR1428671A (en) 1966-02-18
CH446370A (en) 1967-11-15
FR4249M (en) 1966-07-29

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