ES307265A1 - A procedure for preparation of 21-diciclohexilmetil-carbonates of steroids. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparation of 21-diciclohexilmetil-carbonates of steroids. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES307265A1
ES307265A1 ES0307265A ES307265A ES307265A1 ES 307265 A1 ES307265 A1 ES 307265A1 ES 0307265 A ES0307265 A ES 0307265A ES 307265 A ES307265 A ES 307265A ES 307265 A1 ES307265 A1 ES 307265A1
Authority
ES
Spain
Prior art keywords
dicyclohexylmethyl
mixed carbonate
prednisolone
translation
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0307265A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to ES0307265A priority Critical patent/ES307265A1/en
Publication of ES307265A1 publication Critical patent/ES307265A1/en
Expired legal-status Critical Current

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  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A procedure for the preparation of steroid 21-dicyclohexylmethyl carbonates corresponding to the general formula ** (See formula) ** and especially: a) the mixed carbonate of dicyclohexylmethyl and dexamethasone, b) the mixed carbonate of dicyclohexylmethyl and of prednisolone, c) the mixed carbonate of dicyclohexylmethyl and of cortisone, d) the mixed carbonate of dicyclohexylmethyl and of hydrocortisone, e) the mixed carbonate of dicyclohexylmethyl and 9-alpha-fluorohydrocortisone, f) the mixed carbonate of dicyclohexylmethyl and prednisone, g) the mixed carbonate of dicyclohexylmethyl and of 9alpha-fluoro prednisone, h) the mixed carbonate of dicyclohexylmethyl and of 9alpha fluoro prednisolone, i) the mixed carbonate of dicyclohexylmethyl and beta-methasone, j) the mixed carbonate of dicyclohexylmethyl and of parametasone, k) the mixed carbonate of dicyclohexylmethyl and of 6-methyl-prednisolone, l) the mixed carbonate of dicyclohexylmethyl and of 9alpha-fluoro-16alpha-hydroxy prednisolone, characterized in that the chosen cortisone derivative is reacted with the dicyclohexylmethyl chloroformate in the presence of a tertiary base , such as pyridine, preferably operating in an organic solvent, such as dioxane or acetone. (Machine-translation by Google Translate, not legally binding)
ES0307265A 1964-12-18 1964-12-18 A procedure for preparation of 21-diciclohexilmetil-carbonates of steroids. (Machine-translation by Google Translate, not legally binding) Expired ES307265A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES0307265A ES307265A1 (en) 1964-12-18 1964-12-18 A procedure for preparation of 21-diciclohexilmetil-carbonates of steroids. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES0307265A ES307265A1 (en) 1964-12-18 1964-12-18 A procedure for preparation of 21-diciclohexilmetil-carbonates of steroids. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES307265A1 true ES307265A1 (en) 1965-08-16

Family

ID=34500126

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0307265A Expired ES307265A1 (en) 1964-12-18 1964-12-18 A procedure for preparation of 21-diciclohexilmetil-carbonates of steroids. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES307265A1 (en)

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