ES279403A1 - A procedure for the preparation of 10-alkenil-delta1,4-3-ceto-steroids (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of 10-alkenil-delta1,4-3-ceto-steroids (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES279403A1
ES279403A1 ES279403A ES279403A ES279403A1 ES 279403 A1 ES279403 A1 ES 279403A1 ES 279403 A ES279403 A ES 279403A ES 279403 A ES279403 A ES 279403A ES 279403 A1 ES279403 A1 ES 279403A1
Authority
ES
Spain
Prior art keywords
steroids
translation
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES279403A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES279403A1 publication Critical patent/ES279403A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)

Abstract

A process for the preparation of 10-alkenyl-delta 1,4-3-keto-steroids, characterized in that it comprises reacting a 3-hydroxy-steroid provided with an aromatic ring A, in alkaline aqueous solution, with a alkenyl compound of the formula **FIGURE** where R1, R2 and R3 each represent hydrogen or lower alkyl, and X is an anion of a strong acid, and isolating a 10-alkenyl-delta 1,4-3-keto-steroid from the reaction mixture. (Machine-translation by Google Translate, not legally binding)
ES279403A 1961-07-21 1962-07-20 A procedure for the preparation of 10-alkenil-delta1,4-3-ceto-steroids (Machine-translation by Google Translate, not legally binding) Expired ES279403A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH861061A CH396893A (en) 1961-07-21 1961-07-21 Process for the preparation of new 10-alkenyl steroids

Publications (1)

Publication Number Publication Date
ES279403A1 true ES279403A1 (en) 1963-03-16

Family

ID=4342588

Family Applications (1)

Application Number Title Priority Date Filing Date
ES279403A Expired ES279403A1 (en) 1961-07-21 1962-07-20 A procedure for the preparation of 10-alkenil-delta1,4-3-ceto-steroids (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
CH (1) CH396893A (en)
DK (1) DK104404C (en)
ES (1) ES279403A1 (en)
FR (1) FR2180M (en)
GB (1) GB948111A (en)

Also Published As

Publication number Publication date
GB948111A (en) 1964-01-29
CH396893A (en) 1965-08-15
FR2180M (en) 1963-12-02
DK104404C (en) 1966-05-16

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