ES275437A1 - Amino-alkylidene-dibenzocycloheptene derivatives - Google Patents

Amino-alkylidene-dibenzocycloheptene derivatives

Info

Publication number
ES275437A1
ES275437A1 ES0275437A ES275437A ES275437A1 ES 275437 A1 ES275437 A1 ES 275437A1 ES 0275437 A ES0275437 A ES 0275437A ES 275437 A ES275437 A ES 275437A ES 275437 A1 ES275437 A1 ES 275437A1
Authority
ES
Spain
Prior art keywords
compounds
formula
alkylidene
amino
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0275437A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH305461A external-priority patent/CH385833A/en
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of ES275437A1 publication Critical patent/ES275437A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/145Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)

Abstract

The invention comprises compounds of general formula <FORM:0974710/C1/1> wherein X1 and X2 either each represent a hydrogen atom or together represent an additional bond, and R1 represents an alkyl radical having at most 5 carbon atoms and their acid addition salts and their preparation by hydrolysing or hydrogenolysing a compound of formula <FORM:0974710/C1/2> wherein Ac represents an organic acid radical or a functional derivative thereof. Acid derivatives II (e.g. N-carbethoxy-methylamino compounds) are prepared from tertiary amines of formula <FORM:0974710/C1/3> wherein R2 is benzyl, alkenyl or alkyl (e.g. dimethylamino compounds) which may themselves be obtained by reaction of the cyclohepten-5-ones with a substituted propyl metal compound followed by dehydration. Pharmaceutical compositions comprise compounds I and salts of the invention with carriers.
ES0275437A 1961-03-14 1962-03-13 Amino-alkylidene-dibenzocycloheptene derivatives Expired ES275437A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH305461A CH385833A (en) 1961-03-14 1961-03-14 Process for the production of new amines
CH385161 1961-03-30

Publications (1)

Publication Number Publication Date
ES275437A1 true ES275437A1 (en) 1962-10-16

Family

ID=25692046

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0275437A Expired ES275437A1 (en) 1961-03-14 1962-03-13 Amino-alkylidene-dibenzocycloheptene derivatives

Country Status (7)

Country Link
BE (1) BE615025A (en)
DE (2) DE1288599B (en)
DK (1) DK131902C (en)
ES (1) ES275437A1 (en)
FR (2) FR1320297A (en)
GB (1) GB974710A (en)
SE (1) SE306528B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR182M (en) * 1958-04-03 Hoffmann La Roche

Also Published As

Publication number Publication date
DK131902C (en) 1976-03-15
DK131902B (en) 1975-09-22
DE1768402C2 (en) 1983-04-07
DE1768402A1 (en) 1969-10-23
FR1320297A (en) 1963-03-08
BE615025A (en) 1962-09-13
SE306528B (en) 1968-12-02
FR2085M (en) 1963-10-21
DE1288599B (en) 1969-02-06
GB974710A (en) 1964-11-11

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