ES269147A1 - Serine derivative - Google Patents
Serine derivativeInfo
- Publication number
- ES269147A1 ES269147A1 ES0269147A ES269147A ES269147A1 ES 269147 A1 ES269147 A1 ES 269147A1 ES 0269147 A ES0269147 A ES 0269147A ES 269147 A ES269147 A ES 269147A ES 269147 A1 ES269147 A1 ES 269147A1
- Authority
- ES
- Spain
- Prior art keywords
- dichloroacetyl
- methyl
- compounds
- inert solvent
- serine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises O-dichloroacetyl-DL-serine derivatives of the general formula <FORM:0911489/IV (b)/1> (wherein R represents hydrogen, methyl or ethyl) and non-toxic addition salts thereof. These compounds may be prepared by reacting serine or its methyl or ethyl ester with glacial dichloroacetic acid and hydrogen chloride gas or dichloroacetic anhydride in the presence of an inert solvent, or by treating the corresponding N-dichloroacetyl compounds with a strong inorganic acid in the presence of an inert solvent. The products have anti-tumour activity, and may be administered with the usual excipients.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB27407/60A GB911489A (en) | 1960-08-08 | 1960-08-08 | Serine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
ES269147A1 true ES269147A1 (en) | 1961-11-16 |
Family
ID=10259072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0269147A Expired ES269147A1 (en) | 1960-08-08 | 1961-07-04 | Serine derivative |
Country Status (5)
Country | Link |
---|---|
BE (1) | BE605281A (en) |
CH (1) | CH395130A (en) |
ES (1) | ES269147A1 (en) |
FR (1) | FR1395M (en) |
GB (1) | GB911489A (en) |
-
1960
- 1960-08-08 GB GB27407/60A patent/GB911489A/en not_active Expired
-
1961
- 1961-06-16 CH CH707861A patent/CH395130A/en unknown
- 1961-06-22 BE BE605281A patent/BE605281A/en unknown
- 1961-07-04 ES ES0269147A patent/ES269147A1/en not_active Expired
- 1961-10-02 FR FR874770A patent/FR1395M/en active Active
Also Published As
Publication number | Publication date |
---|---|
FR1395M (en) | 1962-07-09 |
GB911489A (en) | 1962-11-28 |
CH395130A (en) | 1965-07-15 |
BE605281A (en) | 1961-12-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB949088A (en) | Diazabicyclo-octane derivatives | |
ES360566A1 (en) | Pyridoxine alpha-ketoglutarate and derivatives thereof | |
GB1386150A (en) | 6-acylaminophenyl-4,5-dihydropyridazones | |
ES269147A1 (en) | Serine derivative | |
GB974718A (en) | Maleimide derivative | |
GB1188249A (en) | 2-Halomethyl-Quinoxaline-1,4-di-N-Oxide-3-Carboxylic Acid Amides | |
GB1059174A (en) | Diazacycloalkane derivatives | |
GB1123466A (en) | Process for the production of cyanamide dicarboxylic acid esters | |
ES290275A2 (en) | Procedure for preparing new compounds for 6-methyl and 1,6-dimethyl-er-golina ii (Machine-translation by Google Translate, not legally binding) | |
JPS5283429A (en) | Preparation of aromatic unsaturated carboxylic acid amide derivatives | |
JPS5266626A (en) | Non-medical fungicide and anti-phytophagineae agent, and their prepara tion | |
ES289117A1 (en) | A procedure for the preparation of new derivatives of 6-methyl and 1,6-dimethyl-8-amino-methyl-ergoline i (Machine-translation by Google Translate, not legally binding) | |
ES358795A1 (en) | Procedure for the preparation of di-N-oxidos- (1,4) quinovalinas 3-carboxamidas. (Machine-translation by Google Translate, not legally binding) | |
JPS52100473A (en) | Novel azimidebenzamide derivative and its production | |
GB1211387A (en) | 0-benzylpiperidine derivative and a process for the preparation thereof | |
ES266124A1 (en) | Esters of 5,7-dibromo-8-hydroxyquinoline and the preparation thereof | |
GB1265866A (en) | ||
GB898101A (en) | Amino acid derivatives | |
GB1054632A (en) | ||
GB936366A (en) | Methylsulphonyl-phenyl compounds | |
GB1217689A (en) | Ethyl esters of fluro-acetic acids | |
GR27998B (en) | METHOD FOR THE PREPARATION OF ESTERS OF THE INDOLIC SERIES. | |
GB1041694A (en) | Substituted pyridine derivatives and preparation thereof | |
GB992796A (en) | Improvements in or relating to c-normorphinan derivatives and their preparation | |
ES289046A1 (en) | A procedure for preparing new derivatives of 6-methyl and 1,6-dimethyl-8- (alpha-hydroxy-alkyl) -ergoline i (Machine-translation by Google Translate, not legally binding) |