ES2684758T3 - Procedimiento para diagnosticar fibrosis hepática - Google Patents
Procedimiento para diagnosticar fibrosis hepática Download PDFInfo
- Publication number
- ES2684758T3 ES2684758T3 ES15720014.8T ES15720014T ES2684758T3 ES 2684758 T3 ES2684758 T3 ES 2684758T3 ES 15720014 T ES15720014 T ES 15720014T ES 2684758 T3 ES2684758 T3 ES 2684758T3
- Authority
- ES
- Spain
- Prior art keywords
- liver fibrosis
- procedure
- diagnose liver
- rdna
- obesity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Un procedimiento in vitro para diagnosticar la fibrosis hepática en un sujeto que padece obesidad, y dicho procedimiento comprende los pasos de: a1) medir la concentración de ADNr 16S bacteriano, o la relación de la cantidad de ADNr 16S bacteriano con la cantidad de ADN total, en una muestra biológica del sujeto seleccionado del grupo que consiste en sangre, suero y muestra de plasma; y b) según el resultado de la medición en el paso a1), diagnosticar fibrosis hepática en el sujeto que padece obesidad.
Description
Claims (1)
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imagen1 imagen2
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14305597 | 2014-04-23 | ||
EP14305597 | 2014-04-23 | ||
PCT/EP2015/058772 WO2015162200A1 (en) | 2014-04-23 | 2015-04-23 | Method for diagnosing hepatic fibrosis |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2684758T3 true ES2684758T3 (es) | 2018-10-04 |
Family
ID=50679975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES15720014.8T Active ES2684758T3 (es) | 2014-04-23 | 2015-04-23 | Procedimiento para diagnosticar fibrosis hepática |
Country Status (5)
Country | Link |
---|---|
US (1) | US10337069B2 (es) |
EP (1) | EP3134543B1 (es) |
CN (1) | CN106661617A (es) |
ES (1) | ES2684758T3 (es) |
WO (1) | WO2015162200A1 (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2017060039A1 (en) * | 2015-10-09 | 2017-04-13 | Vaiomer | Method for diagnosing hepatic fibrosis based on bacterial profile and diversity |
CN110229877A (zh) * | 2019-06-21 | 2019-09-13 | 广东药科大学附属第一医院 | 一种miRNA在制备预防或诊断血脂异常肝郁证试剂中的应用 |
RU2759672C2 (ru) * | 2019-12-12 | 2021-11-16 | Федеральное бюджетное учреждение науки "Санкт-Петербургский научно-исследовательский институт эпидемиологии и микробиологии им. Пастера Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека" (ФБУН НИИ эпидемиологии и микробиологии имени Пастера) | Способ дифференциации причин развития фиброза печени начального уровня при хронических вирусных гепатитах В и С |
CN112819785B (zh) * | 2021-02-01 | 2024-06-07 | 北京精康科技有限责任公司 | 一种肝脏血液动力检测装置 |
CN112819786B (zh) * | 2021-02-01 | 2023-11-28 | 北京精康科技有限责任公司 | 基于多个肝静脉波形图的肝脏血液动力检测装置 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007130636A2 (en) * | 2006-05-03 | 2007-11-15 | Geisinger Clinic | Methods for diagnosing and predicting non-alcoholic steatohepatitis (nash) |
US20120021421A1 (en) * | 2009-02-13 | 2012-01-26 | Jacques Amar | Bacterial DNA as Markers of Cardiovascular and/or Metabolic Disease |
EP2691537A1 (en) * | 2011-03-31 | 2014-02-05 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Method for predicting abdominal obesity |
US20140186829A1 (en) | 2011-03-31 | 2014-07-03 | Chu De Toulouse | Method for predicting insulinopenic type 2 diabetes |
-
2015
- 2015-04-23 EP EP15720014.8A patent/EP3134543B1/en active Active
- 2015-04-23 WO PCT/EP2015/058772 patent/WO2015162200A1/en active Application Filing
- 2015-04-23 CN CN201580027331.7A patent/CN106661617A/zh active Pending
- 2015-04-23 ES ES15720014.8T patent/ES2684758T3/es active Active
- 2015-04-23 US US15/305,598 patent/US10337069B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20170044612A1 (en) | 2017-02-16 |
EP3134543A1 (en) | 2017-03-01 |
WO2015162200A1 (en) | 2015-10-29 |
US10337069B2 (en) | 2019-07-02 |
EP3134543B1 (en) | 2018-04-11 |
CN106661617A (zh) | 2017-05-10 |
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