ES2579161R1 - Nanofibras híbridas de aloe vera - Google Patents
Nanofibras híbridas de aloe vera Download PDFInfo
- Publication number
- ES2579161R1 ES2579161R1 ES201600173A ES201600173A ES2579161R1 ES 2579161 R1 ES2579161 R1 ES 2579161R1 ES 201600173 A ES201600173 A ES 201600173A ES 201600173 A ES201600173 A ES 201600173A ES 2579161 R1 ES2579161 R1 ES 2579161R1
- Authority
- ES
- Spain
- Prior art keywords
- hybrid nanofibers
- aloe vera
- poly
- nanofibers
- hybrid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/26—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/005—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters containing a biologically active substance, e.g. a medicament or a biocide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/06—At least partially resorbable materials
- A61L17/10—At least partially resorbable materials containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/005—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/32—Materials or treatment for tissue regeneration for nerve reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Nanotechnology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Botany (AREA)
- Crystallography & Structural Chemistry (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Urology & Nephrology (AREA)
- Materials For Medical Uses (AREA)
- Artificial Filaments (AREA)
- Nonwoven Fabrics (AREA)
- Jellies, Jams, And Syrups (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Abstract.#La presente invención proporciona nanofibras híbridas que comprenden una mezcla de los componentes de un gel de aloe vera y un polímero sintético seleccionado de poli-3-hidroxibutirato-co-3-hidroxivalerato (PHBV), ácido poli-L-láctico (PLLA) y polidioxanona (PDS), y donde el diámetro promedio de las nanofibras híbridas está comprendido entre 0,3 y 1,5 micras. Asimismo, la presente invención proporciona un método de fabricación de dichas nanofibras híbridas.#Las nanofibras híbridas de la invención pueden ser usadas en prótesis tubulares de reconexión nerviosa tras axotomía de nervios periféricos, en apósitos y suturas para mejorar la reinervación, y por tanto la recuperación sensitiva, de lesiones en órganos sensoriales como la piel (ej. quemaduras, úlceras, incisiones quirúrgicas, etc.) entre otros.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201600173A ES2579161B2 (es) | 2016-03-08 | 2016-03-08 | Nanofibras híbridas de aloe vera |
EP18173213.2A EP3461788B1 (en) | 2016-03-08 | 2017-03-02 | Hybrid honey nanofibers |
DK18173213.2T DK3461788T3 (da) | 2016-03-08 | 2017-03-02 | Hybride honningnanofibre |
PCT/ES2017/000029 WO2017153619A1 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de aloe vera |
ES17762582T ES2930322T3 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de aloe vera |
EP17762582.9A EP3428117B1 (en) | 2016-03-08 | 2017-03-02 | Hybrid aloe vera nanofibres |
DK17762582.9T DK3428117T3 (en) | 2016-03-08 | 2017-03-02 | Hybride Aloe-vera-nanofibre |
ES18173213T ES2930808T3 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de miel |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES201600173A ES2579161B2 (es) | 2016-03-08 | 2016-03-08 | Nanofibras híbridas de aloe vera |
Publications (3)
Publication Number | Publication Date |
---|---|
ES2579161A2 ES2579161A2 (es) | 2016-08-05 |
ES2579161R1 true ES2579161R1 (es) | 2016-09-30 |
ES2579161B2 ES2579161B2 (es) | 2017-03-28 |
Family
ID=56551049
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES201600173A Active ES2579161B2 (es) | 2016-03-08 | 2016-03-08 | Nanofibras híbridas de aloe vera |
ES17762582T Active ES2930322T3 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de aloe vera |
ES18173213T Active ES2930808T3 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de miel |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES17762582T Active ES2930322T3 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de aloe vera |
ES18173213T Active ES2930808T3 (es) | 2016-03-08 | 2017-03-02 | Nanofibras híbridas de miel |
Country Status (4)
Country | Link |
---|---|
EP (2) | EP3461788B1 (es) |
DK (2) | DK3461788T3 (es) |
ES (3) | ES2579161B2 (es) |
WO (1) | WO2017153619A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020049339A1 (en) * | 2018-09-06 | 2020-03-12 | Bio-On S.P.A. | Membrane to re-establish continuity of injured biological tissues |
US20210322633A1 (en) * | 2018-09-06 | 2021-10-21 | Bio-On S.P.A. | Medical device for use in the regeneration of an injured nerve |
CN110812530B (zh) * | 2019-11-26 | 2021-11-02 | 东华大学 | 一种phbv提高plla的形状记忆和促成骨效应的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009133056A1 (fr) * | 2008-04-29 | 2009-11-05 | Commissariat A L'energie Atomique | Interface a retour d'effort a sensation ameliorée |
WO2013035072A1 (en) * | 2011-09-08 | 2013-03-14 | Vile Glenn | Bioactive nanofibres |
WO2014027965A1 (en) * | 2012-08-15 | 2014-02-20 | National University Of Singapore | Wound dressing nanomesh impregnated with human umbilical cord wharton's jelly stem cells |
WO2014142675A1 (en) * | 2013-03-12 | 2014-09-18 | Active Fibres Limited | Nanofibre and bioactive compositions and related methods |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009133059A2 (en) * | 2008-05-02 | 2009-11-05 | Evonik Degussa Gmbh | Nanofiber matrices formed from electrospun hyperbranched polymers |
GB2484319A (en) * | 2010-10-06 | 2012-04-11 | Univ Bolton | Electrospinning fibres comprising honey and biocompatible polymer |
WO2015157485A1 (en) * | 2014-04-10 | 2015-10-15 | The Johns Hopkins University | Device and method for a nanofiber wrap to minimize inflamation and scarring |
WO2015183228A1 (en) * | 2014-05-27 | 2015-12-03 | Duymuş Ethem | Nano fiber cover for wounds and ambustions with an additive containing natural antiseptic |
-
2016
- 2016-03-08 ES ES201600173A patent/ES2579161B2/es active Active
-
2017
- 2017-03-02 EP EP18173213.2A patent/EP3461788B1/en active Active
- 2017-03-02 DK DK18173213.2T patent/DK3461788T3/da active
- 2017-03-02 ES ES17762582T patent/ES2930322T3/es active Active
- 2017-03-02 ES ES18173213T patent/ES2930808T3/es active Active
- 2017-03-02 WO PCT/ES2017/000029 patent/WO2017153619A1/es unknown
- 2017-03-02 EP EP17762582.9A patent/EP3428117B1/en active Active
- 2017-03-02 DK DK17762582.9T patent/DK3428117T3/da active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009133056A1 (fr) * | 2008-04-29 | 2009-11-05 | Commissariat A L'energie Atomique | Interface a retour d'effort a sensation ameliorée |
WO2013035072A1 (en) * | 2011-09-08 | 2013-03-14 | Vile Glenn | Bioactive nanofibres |
WO2014027965A1 (en) * | 2012-08-15 | 2014-02-20 | National University Of Singapore | Wound dressing nanomesh impregnated with human umbilical cord wharton's jelly stem cells |
WO2014142675A1 (en) * | 2013-03-12 | 2014-09-18 | Active Fibres Limited | Nanofibre and bioactive compositions and related methods |
Non-Patent Citations (2)
Title |
---|
Prabhakaran Molamma P, et al. "Electrospun aligned PHBV/collagen nanofibers as substrates for nerve tissue engineering", Biotechnology and bioengineering vol.110nº 10, pág. 2775 - 2784; (2013-04-29) resumen * |
Suganya S. et al.: "Naturally derived biofunctional nanofibrous scaffold for skin tissue regeneration", International Journal of Biological Macromolecules, páginas 135 - 143 Julio 2014 (2014-07-00)resumen * |
Also Published As
Publication number | Publication date |
---|---|
WO2017153619A1 (es) | 2017-09-14 |
ES2579161A2 (es) | 2016-08-05 |
DK3461788T3 (da) | 2022-10-31 |
DK3428117T3 (en) | 2022-10-17 |
ES2579161B2 (es) | 2017-03-28 |
EP3428117B1 (en) | 2022-07-27 |
EP3461788A1 (en) | 2019-04-03 |
ES2930322T3 (es) | 2022-12-09 |
EP3428117A4 (en) | 2019-11-13 |
ES2930808T3 (es) | 2022-12-22 |
EP3428117A1 (en) | 2019-01-16 |
EP3461788B1 (en) | 2022-10-12 |
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