ES2576464R1 - Procesado sin disolvente, sistema y métodos - Google Patents

Procesado sin disolvente, sistema y métodos Download PDF

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Publication number
ES2576464R1
ES2576464R1 ES201690022A ES201690022A ES2576464R1 ES 2576464 R1 ES2576464 R1 ES 2576464R1 ES 201690022 A ES201690022 A ES 201690022A ES 201690022 A ES201690022 A ES 201690022A ES 2576464 R1 ES2576464 R1 ES 2576464R1
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Spain
Prior art keywords
solvent
processed
methods
chemical constituents
extracted
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201690022A
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English (en)
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ES2576464B2 (es
ES2576464A2 (es
Inventor
C. RABER Jeffrey
Sytze Elzinga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Werc Shop LLC
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Werc Shop LLC
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Publication of ES2576464A2 publication Critical patent/ES2576464A2/es
Publication of ES2576464R1 publication Critical patent/ES2576464R1/es
Application granted granted Critical
Publication of ES2576464B2 publication Critical patent/ES2576464B2/es
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00—Purification; Separation; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C10—PETROLEUM, GAS OR COKE INDUSTRIES; TECHNICAL GASES CONTAINING CARBON MONOXIDE; FUELS; LUBRICANTS; PEAT
    • C10G—CRACKING HYDROCARBON OILS; PRODUCTION OF LIQUID HYDROCARBON MIXTURES, e.g. BY DESTRUCTIVE HYDROGENATION, OLIGOMERISATION, POLYMERISATION; RECOVERY OF HYDROCARBON OILS FROM OIL-SHALE, OIL-SAND, OR GASES; REFINING MIXTURES MAINLY CONSISTING OF HYDROCARBONS; REFORMING OF NAPHTHA; MINERAL WAXES
    • C10G17/00—Refining of hydrocarbon oils in the absence of hydrogen, with acids, acid-forming compounds or acid-containing liquids, e.g. acid sludge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/028—Flow sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0288—Applications, solvents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/50—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/02—Marketing; Price estimation or determination; Fundraising
    • G06Q30/0241—Advertisements
    • G06Q30/0251—Targeted advertisements
    • G06Q30/0269—Targeted advertisements based on user profile or attribute
    • G—PHYSICS
    • G06—COMPUTING; CALCULATING OR COUNTING
    • G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
    • G06Q30/00—Commerce
    • G06Q30/02—Marketing; Price estimation or determination; Fundraising
    • G06Q30/0241—Advertisements
    • G06Q30/0251—Targeted advertisements
    • G06Q30/0269—Targeted advertisements based on user profile or attribute
    • G06Q30/0271—Personalized advertisement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0207—Control systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Business, Economics & Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Strategic Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Finance (AREA)
  • Development Economics (AREA)
  • Biomedical Technology (AREA)
  • Accounting & Taxation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Game Theory and Decision Science (AREA)
  • General Business, Economics & Management (AREA)
  • Entrepreneurship & Innovation (AREA)
  • Theoretical Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Physics & Mathematics (AREA)
  • Economics (AREA)
  • Marketing (AREA)
  • Physics & Mathematics (AREA)

Abstract

Procesado sin disolvente, sistema y métodos.#Se divulga un proceso para purificar uno o más constituyentes químicos a partir de un material vegetal usando extracción con un fluido que no es un disolvente, por ejemplo, un aceite vegetal. Los constituyentes químicos extraídos se pueden procesar después opcionalmente mediante calentamiento con el fin de inducir las transformaciones químicas deseadas. Los constituyentes químicos extraídos también se procesan mediante concentración a presión reducida, por ejemplo, mediante destilación.
ES201690022A 2013-11-11 2014-11-10 Procesado sin disolvente, sistema y métodos Active ES2576464B2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361902388P 2013-11-11 2013-11-11
US61/902,388 2013-11-11

Publications (3)

Publication Number Publication Date
ES2576464A2 ES2576464A2 (es) 2016-07-07
ES2576464R1 true ES2576464R1 (es) 2016-07-22
ES2576464B2 ES2576464B2 (es) 2017-01-26

Family

ID=53042200

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201690022A Active ES2576464B2 (es) 2013-11-11 2014-11-10 Procesado sin disolvente, sistema y métodos

Country Status (9)

Country Link
US (3) US9732009B2 (es)
JP (1) JP2017501971A (es)
AU (1) AU2014346466A1 (es)
CA (1) CA2930266A1 (es)
ES (1) ES2576464B2 (es)
GB (1) GB2536150A (es)
IL (1) IL245469A (es)
RU (1) RU2659778C1 (es)
WO (1) WO2015070167A1 (es)

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GB2536150A (en) * 2013-11-11 2016-09-07 The Werc Shop Llc Solvent-free processing, system and methods
EP3150264A1 (de) * 2015-09-30 2017-04-05 Bionorica Ethics GmbH Vakuumdestillation zur anreicherung von cbd
CA3022553C (en) * 2016-05-06 2023-02-21 Zeyead GHARIB The manufacturing methods, compositions, and medical applications of orally administered cannabis pharmaceuticals
US10499584B2 (en) 2016-05-27 2019-12-10 New West Genetics Industrial hemp Cannabis cultivars and seeds with stable cannabinoid profiles
WO2018000094A1 (en) 2016-06-29 2018-01-04 CannScience Innovations Inc. Decarboxylated cannabis resins, uses thereof and methods of making same
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
WO2018118197A1 (en) * 2016-12-21 2018-06-28 Richard Postrel Healthier aging in domesticated animals
WO2018175259A1 (en) * 2017-03-18 2018-09-27 Mcgarrah Steven M Pet food including cannabidiolic acid
CA2987979A1 (en) * 2017-12-07 2019-06-07 Tresvertol Inc. Solvent-free thca extraction process
EP3453397A1 (en) * 2017-09-12 2019-03-13 Albert Jan Dijkstra Processes for the isolation of a cannabinoid extract and product from cannabis plant material
US9987567B1 (en) * 2017-09-29 2018-06-05 NextLeaf Solutions Ltd. Cannabinoid extraction process and system
US11202771B2 (en) 2018-01-31 2021-12-21 Treehouse Biotech, Inc. Hemp powder
US10427067B1 (en) 2018-03-26 2019-10-01 Extractcraft, Llc Controlling heat flux during distillation and concentration of extract
WO2019207554A1 (en) * 2018-04-27 2019-10-31 Radient Technologies Inc. Extraction of compounds from cannabis biomass using food-grade solvent
WO2019211797A1 (en) * 2018-05-03 2019-11-07 Radient Technologies Inc. Method of decarboxylating acidic cannabinoids in cannabis extract suspended within a carrier fluid
US11946016B2 (en) * 2018-06-14 2024-04-02 Biosoma B.V. Process for the extraction of oil-soluble components from plant material
CA3119729A1 (en) 2018-10-10 2020-04-16 Treehouse Biotech, Inc. Synthesis of cannabigerol
US10799812B2 (en) 2019-01-11 2020-10-13 Gildrien Farm, LLC Method of extracting one or more chemical extracts from a plant product
US10512856B1 (en) 2019-01-11 2019-12-24 Gildrien Farm, LLC Method of extracting one or more chemical extracts from a plant product
US10765966B2 (en) 2019-02-06 2020-09-08 Heinkel Filtering Systems. Inc. Biomass extraction and centrifugation systems and methods
US10493377B1 (en) 2019-02-06 2019-12-03 Heinkel Filtering Systems, Inc. Biomass extraction and centrifugation systems and methods
US11370767B2 (en) * 2019-04-23 2022-06-28 Soma Oil Llc Cannabis processing systems and methods
WO2021016717A1 (en) * 2019-07-31 2021-02-04 Canopy Growth Corporation Separation of cannabinoids from mixtures thereof by extraction and distillation
CA3150757A1 (en) * 2019-08-20 2021-02-25 Scott E. Craig Apparatus and method for extracting essential oils
BR112022003557A2 (pt) 2019-08-27 2022-05-24 Herbolea Biotech S P A Concentrado e isolado de canabinoide, método de obtenção dos mesmos e uso dos mesmos
US10717056B1 (en) 2019-09-09 2020-07-21 Michael Cem Gokay Method and apparatus for purification of cannabinoid extracts
US11542243B1 (en) * 2019-09-26 2023-01-03 FusionFarms, LLC Method of converting delta9-THC to delta10-THC and the purification of the delta10-THC by crystallization
US10858303B1 (en) 2019-10-30 2020-12-08 Heinkel Filtering Systems, Inc. Cannabidiol isolate production systems and methods
US10751640B1 (en) 2019-10-30 2020-08-25 Heinkel Filtering Systems, Inc. Cannabidiol isolate production systems and methods
WO2022178625A1 (en) * 2021-02-23 2022-09-01 Evo Extracts Inc. Pressure distillation apparatus
US11987775B1 (en) * 2022-03-15 2024-05-21 Elidan Dynamic, LLC Systems and methods for extracting THC from cannabis plants

Citations (5)

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US20040147767A1 (en) * 2001-05-04 2004-07-29 Brian Whittle Processes and apparatus for extraction of active substances and enriched extracts from natural products
US20120095087A1 (en) * 2010-10-15 2012-04-19 Keith Hyatt Enhanced products by sustainable processes for medicinal use
EP1536810B1 (en) * 2002-08-14 2012-08-01 GW Pharma Limited Extraction of pharmaceutically active cannabinoids from plant materials
US20130184354A1 (en) * 2012-01-13 2013-07-18 Donna K. Jackson Silicone and Hylauronic Acid (HLA) Delivery Systems for Products by Sustainable Processes for Medical Uses Including Wound Management
WO2013165251A1 (en) * 2012-05-03 2013-11-07 Echo Pharmaceuticals B.V. Cannabis plant isolate comprising /\9-tetrahydrocannabinol and a method for preparing such an isolate

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GB0222077D0 (en) * 2002-09-23 2002-10-30 Gw Pharma Ltd Methods of preparing cannabinoids from plant material
JP2006320308A (ja) 2005-04-19 2006-11-30 Yuho:Kk 動・植物エキス溶液の製造方法、動・植物エキス溶液及びこれを含有してなる健康飲料・食品、化粧品又は医薬品
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GB2536150A (en) * 2013-11-11 2016-09-07 The Werc Shop Llc Solvent-free processing, system and methods

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040147767A1 (en) * 2001-05-04 2004-07-29 Brian Whittle Processes and apparatus for extraction of active substances and enriched extracts from natural products
EP1536810B1 (en) * 2002-08-14 2012-08-01 GW Pharma Limited Extraction of pharmaceutically active cannabinoids from plant materials
US20120095087A1 (en) * 2010-10-15 2012-04-19 Keith Hyatt Enhanced products by sustainable processes for medicinal use
US20130184354A1 (en) * 2012-01-13 2013-07-18 Donna K. Jackson Silicone and Hylauronic Acid (HLA) Delivery Systems for Products by Sustainable Processes for Medical Uses Including Wound Management
WO2013165251A1 (en) * 2012-05-03 2013-11-07 Echo Pharmaceuticals B.V. Cannabis plant isolate comprising /\9-tetrahydrocannabinol and a method for preparing such an isolate

Also Published As

Publication number Publication date
GB2536150A (en) 2016-09-07
ES2576464B2 (es) 2017-01-26
CA2930266A1 (en) 2015-05-14
JP2017501971A (ja) 2017-01-19
RU2016117582A (ru) 2017-12-19
US9732009B2 (en) 2017-08-15
US20210130254A1 (en) 2021-05-06
US20180016203A1 (en) 2018-01-18
ES2576464A2 (es) 2016-07-07
US11072568B2 (en) 2021-07-27
WO2015070167A1 (en) 2015-05-14
AU2014346466A1 (en) 2016-05-19
US20150152018A1 (en) 2015-06-04
IL245469A0 (en) 2016-06-30
GB201608256D0 (en) 2016-06-22
RU2659778C1 (ru) 2018-07-04
IL245469A (en) 2017-02-28

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