ES2568232T3 - Apósitos para heridas - Google Patents
Apósitos para heridas Download PDFInfo
- Publication number
- ES2568232T3 ES2568232T3 ES13728838.7T ES13728838T ES2568232T3 ES 2568232 T3 ES2568232 T3 ES 2568232T3 ES 13728838 T ES13728838 T ES 13728838T ES 2568232 T3 ES2568232 T3 ES 2568232T3
- Authority
- ES
- Spain
- Prior art keywords
- collagen
- pvp
- wound dressings
- suspension
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F15/00—Auxiliary appliances for wound dressings; Dispensing containers for dressings or bandages
- A61F15/001—Packages or dispensers for bandages, cotton balls, drapes, dressings, gauze, gowns, sheets, sponges, swabsticks or towels
- A61F15/002—Packages or dispensers for bandages, cotton balls, drapes, dressings, gauze, gowns, sheets, sponges, swabsticks or towels dispensers for web or tape like bandages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
- A61L15/325—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/46—Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/106—Halogens or compounds thereof, e.g. iodine, chlorite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Materials For Medical Uses (AREA)
Abstract
Un material sólido de apósito para heridas que comprende: del 7%p al 25%p de colágeno; del 20%p al 70%p de Cadexómero-yodo; y no más del 10%p de agua, en el que los porcentajes en peso se basan en el peso seco de la composición.
Description
pasta de PVP-I y glicerol.
Tabla 1
- ID de suspensiónnº
- Suspensión de colágeno / g Ácido acético (0,05 M) / ml Pasta de PVP-I / g Glicerol / ml
- 1
- 99,5 96,5 0 4
- 2
- 99,5 94,3 2,2125 4
- 3
- 99,5 92,0 4,5 4
- 4
- 99,5 87,6 8,9
- 4
- 5
- 99,5 78,7 17,8 4
- 6
- 99,5 60,9 35,6 4
- 7
- 91,3 39,6 65,4 3,7
- 8
- 99,5 7,5 89,0 4
La suspensión de colágeno contuvo colágeno bovino (2,01% de sólidos en ácido acético acuoso de pH 2,9-3,1). Se 5 tuvo cuidado de no manipular en exceso el colágeno.
La pasta de PVP-I contuvo un 48,63% de Lutrol 400 (un polietilen glicol que tiene un peso molecular medio de 400 y una fórmula general HO-[-CH2-CH2-O-]n-H, en la que n = 8); 35,73% de PEG 4000; 10,68% de PVP-I y 4,96% de agua.
Las suspensiones producidas se desgasificaron en una cámara de vacío y se vertieron en placas de 100 cm2 tal 10 como se indica en la Tabla 2. Se calculó el porcentaje de PVP-I y de colágeno en las composiciones húmedas, y también se muestra en la Tabla 2.
Tabla 2
- ID de película
- ID de suspensión nº (véase laTabla 1) Suspensión añadida a placa de 100 cm2 / g Col. por placa de 100 cm2 / g PVP-I por placa de 100 cm2 / g %p de PVP-I en la composición húmeda %p de col en la composiciónhúmeda
- CC1*
- 1 62 0,617 0,00 0% 0,99%
- CC2*
- 1 93 0,925 0,00 0% 0,99%
- A*
- 2 62 0,617 0,073 0,12% 0,99%
- B*
- 2 93 0,925 0,109 0,12% 0,99%
- C*
- 3 93 0,925 0,222 0,24% 0,99%
- D
- 4 93 0,925 0,440 0,47% 0,99%
- E
- 5 62 0,617 0,586 0,95% 0,99%
- F*
- 6 93 0,925 1,759 1,89% 0,99%
- G*
- 7 93 0,849 3,232 3,48% 0,91%
- H*
- 8 62 0,617 2,931 4,73% 0,99%
col = colágeno; CC = Control de colágeno; * = ejemplo de referencia
Las películas se secaron durante la noche en aire hasta que estuvieron secas al tacto. Basándose en la pérdida de peso tras el secado, se dedujo que se eliminó más del 90% del agua y ácido acético presentes en un principio en la 15 suspensión tras el secado. Las composiciones en porcentaje calculadas de las películas secas se muestran en la Tabla 3. Los porcentajes se calculan basándose en el peso seco, es decir, basándose en todos los componentes de
6
Claims (1)
-
imagen1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB201207617 | 2012-05-02 | ||
| GBGB1207617.0A GB201207617D0 (en) | 2012-05-02 | 2012-05-02 | Wound dressings |
| PCT/IB2013/053448 WO2013164774A1 (en) | 2012-05-02 | 2013-05-01 | Wound dressings |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2568232T3 true ES2568232T3 (es) | 2016-04-28 |
Family
ID=46330630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES13728838.7T Active ES2568232T3 (es) | 2012-05-02 | 2013-05-01 | Apósitos para heridas |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10076586B2 (es) |
| EP (2) | EP2844306B1 (es) |
| JP (1) | JP6290184B2 (es) |
| AU (1) | AU2013255442B2 (es) |
| BR (1) | BR112014027263A2 (es) |
| CA (1) | CA2872339A1 (es) |
| ES (1) | ES2568232T3 (es) |
| GB (1) | GB201207617D0 (es) |
| WO (1) | WO2013164774A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016042406A1 (en) * | 2014-09-19 | 2016-03-24 | Galia Textil | Impregnated dry substrates for a dressing material, method and system for manufacturing the same |
| GB201507002D0 (en) * | 2015-04-24 | 2015-06-10 | Medical Res Council | Copper Oxo-hydroxide nanoparticles and their uses as biocidal agents |
| US11097031B2 (en) | 2016-08-01 | 2021-08-24 | The Procter & Gamble Company | Phase-stable, sprayable freshening compositions comprising suspended particles |
| KR102250068B1 (ko) | 2016-08-01 | 2021-05-11 | 더 프록터 앤드 갬블 캄파니 | 현탁된 입자를 포함하는 상-안정하고 분무 가능한 청향 조성물 |
| USD1006236S1 (en) * | 2019-10-07 | 2023-11-28 | 3M Innovative Properties Company | Wound dressing |
| GB2588440A (en) * | 2019-10-24 | 2021-04-28 | Io Cyte Ltd | Swellable antimicrobial fibre |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3224382A1 (de) * | 1982-06-30 | 1984-01-12 | Beiersdorf Ag, 2000 Hamburg | Verbandmaterial auf hydrogelbasis und verfahren zu dessen herstellung |
| US5322695A (en) * | 1987-01-09 | 1994-06-21 | Hercon Laboratories Corporation | Moisture-vapor-permeable dressing |
| US5128136A (en) * | 1990-07-16 | 1992-07-07 | The Oregon Health Sciences University | Wound healing kit comprised of gelable collagen |
| CA2317066A1 (en) * | 1997-10-03 | 1999-04-15 | Lavipharm Laboratories, Inc. | A prolamine-plant polar lipid composition, its method of preparation and applications thereof |
| JP2001017533A (ja) * | 1999-07-02 | 2001-01-23 | Terumo Corp | 皮膚潰瘍補填修復材料 |
| US6592890B1 (en) * | 1999-10-20 | 2003-07-15 | Oxibio, Inc. | Conveyance of anti-infective activity to wound dressings |
| US6399092B1 (en) * | 2000-12-27 | 2002-06-04 | Healthpoint, Ltd. | Anhydrous, hydrophilic absorbent wound dressing (tube) with antimicrobials or other pharmaceutically active agents |
| GB2382775B (en) * | 2001-12-06 | 2005-05-25 | Johnson & Johnson Medical Ltd | Controlled release therapeutic wound dressings |
| GB2399289B (en) * | 2003-03-10 | 2006-03-08 | Johnson & Johnson Medical Ltd | Hydrocolloid materials for use in wound healing |
| GB2408206B (en) * | 2003-11-18 | 2007-11-28 | Johnson & Johnson Medical Ltd | Antioxidant and antimicrobial wound dressing materials |
| GB2410748A (en) * | 2004-02-03 | 2005-08-10 | Johnson & Johnson Medical Ltd | Medicated polyurethane foams |
| US20050191270A1 (en) * | 2004-02-27 | 2005-09-01 | Hydromer, Inc. | Anti-infectious hydrogel compositions |
| JP2005325165A (ja) * | 2004-05-12 | 2005-11-24 | Three M Innovative Properties Co | １００℃以下の温度で溶融塗布可能なヨウ素含有ホットメルト粘着剤および該粘着剤を用いた医療用粘着シート製品 |
| EA016776B9 (ru) * | 2004-09-30 | 2012-11-30 | Ковалон Текнолоджиз Инк. | Неадгезивные эластичные желатиновые матрицы |
| WO2007061942A2 (en) * | 2005-11-18 | 2007-05-31 | Glanbia Nutritionals (Ireland) Ltd. | Compositions for disrupting and inhibiting reconstitution of wound biofilm |
| GB2433029A (en) * | 2005-12-09 | 2007-06-13 | Ethicon Inc | Wound dressings comprising oxidized cellulose and human recombinant collagen |
| KR20100027091A (ko) * | 2006-11-15 | 2010-03-10 | 코다 테라퓨틱스, 인크. | 상처 치유를 위한 개선 방법 및 조성물 |
| AU2009320153B2 (en) * | 2008-10-27 | 2016-07-14 | Trustees Of Tufts College | Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds, and uses thereof |
| AU2010270723A1 (en) * | 2009-07-06 | 2012-02-09 | Molycorp Minerals Llc | Ceria for use as an antimicrobial barrier and disinfectant in a wound dressing |
-
2012
- 2012-05-02 GB GBGB1207617.0A patent/GB201207617D0/en not_active Ceased
-
2013
- 2013-05-01 AU AU2013255442A patent/AU2013255442B2/en not_active Ceased
- 2013-05-01 BR BR112014027263A patent/BR112014027263A2/pt active Search and Examination
- 2013-05-01 WO PCT/IB2013/053448 patent/WO2013164774A1/en active Application Filing
- 2013-05-01 ES ES13728838.7T patent/ES2568232T3/es active Active
- 2013-05-01 EP EP13728838.7A patent/EP2844306B1/en not_active Not-in-force
- 2013-05-01 US US14/398,696 patent/US10076586B2/en active Active
- 2013-05-01 CA CA2872339A patent/CA2872339A1/en not_active Abandoned
- 2013-05-01 EP EP16154651.0A patent/EP3040087B1/en not_active Not-in-force
- 2013-05-01 JP JP2015509550A patent/JP6290184B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2013255442B2 (en) | 2017-03-16 |
| JP2015515877A (ja) | 2015-06-04 |
| AU2013255442A1 (en) | 2014-11-27 |
| EP2844306B1 (en) | 2016-03-16 |
| GB201207617D0 (en) | 2012-06-13 |
| CA2872339A1 (en) | 2013-11-07 |
| US10076586B2 (en) | 2018-09-18 |
| BR112014027263A2 (pt) | 2017-06-27 |
| EP3040087A1 (en) | 2016-07-06 |
| WO2013164774A1 (en) | 2013-11-07 |
| US20150096912A1 (en) | 2015-04-09 |
| EP2844306A1 (en) | 2015-03-11 |
| JP6290184B2 (ja) | 2018-03-07 |
| EP3040087B1 (en) | 2018-06-20 |
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