ES2527664T3 - Tratamiento de la cistitis intersticial con una dosis alta de sulfato de condroitina - Google Patents
Tratamiento de la cistitis intersticial con una dosis alta de sulfato de condroitina Download PDFInfo
- Publication number
- ES2527664T3 ES2527664T3 ES04711966.4T ES04711966T ES2527664T3 ES 2527664 T3 ES2527664 T3 ES 2527664T3 ES 04711966 T ES04711966 T ES 04711966T ES 2527664 T3 ES2527664 T3 ES 2527664T3
- Authority
- ES
- Spain
- Prior art keywords
- treatment
- chondroitin sulfate
- interstitial cystitis
- high dose
- insufficiency
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 title abstract 2
- 229920001287 Chondroitin sulfate Polymers 0.000 title abstract 2
- 208000005615 Interstitial Cystitis Diseases 0.000 title abstract 2
- 229940059329 chondroitin sulfate Drugs 0.000 title abstract 2
- 239000008135 aqueous vehicle Substances 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 201000003146 cystitis Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 210000001635 urinary tract Anatomy 0.000 abstract 1
- 208000019206 urinary tract infection Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Una composición farmacéutica para utilizar en el tratamiento de un paciente humano que padece cistitis intersticial o afecciones vesicales y/o de las vías urinarias relacionadas, mediante la administración por instilación en la vejiga del paciente, donde las afecciones relacionadas son formas de cistitis con insuficiencia de GAG o insuficiencia de GAG que acompaña a una infección crónica de las vías urinarias, y donde la composición consiste en una dosis unitaria de sulfato de condroitina en una cantidad de al menos 400 mg y un vehículo acuoso.
Description
Claims (1)
-
imagen1
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US367970 | 2003-02-19 | ||
US10/367,970 US20040161476A1 (en) | 2003-02-19 | 2003-02-19 | Cystitis treatment with high dose chondroitin sulfate |
PCT/CA2004/000244 WO2004073584A2 (en) | 2003-02-19 | 2004-02-18 | Cystitis treatment with high dose chondroitin sulfate |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2527664T3 true ES2527664T3 (es) | 2015-01-28 |
Family
ID=32850064
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES04711966.4T Expired - Lifetime ES2527664T3 (es) | 2003-02-19 | 2004-02-18 | Tratamiento de la cistitis intersticial con una dosis alta de sulfato de condroitina |
Country Status (15)
Country | Link |
---|---|
US (5) | US20040161476A1 (es) |
EP (2) | EP2857024A1 (es) |
JP (1) | JP4778888B2 (es) |
CN (1) | CN1758920B (es) |
AU (1) | AU2004212650B2 (es) |
CA (1) | CA2515512C (es) |
CY (1) | CY1116069T1 (es) |
DE (1) | DE14189577T9 (es) |
DK (1) | DK1603578T3 (es) |
ES (1) | ES2527664T3 (es) |
HK (2) | HK1085136A1 (es) |
IL (2) | IL170309A (es) |
PT (1) | PT1603578E (es) |
SI (1) | SI1603578T1 (es) |
WO (1) | WO2004073584A2 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040161476A1 (en) | 2003-02-19 | 2004-08-19 | Hahn Sungtack Samuel | Cystitis treatment with high dose chondroitin sulfate |
US20070173479A1 (en) * | 2003-12-10 | 2007-07-26 | Keryx Biopharmaceuticals, Inc. | Methods Using Sulodexide for the Treatment of Bladder Disease |
PT1708722E (pt) | 2004-01-28 | 2014-09-12 | Univ California | Nova terapia interstciial para o alívio imediato dos sintomas e terapia crónica na cistite intersticial |
ITMI20061030A1 (it) * | 2006-05-26 | 2007-11-27 | Altergon Sa | Nuova composizione comprendente glicosamminoglicani a viscosita' controllata e uso di tale composizione nella terapuia della cistite cronica |
US20090023637A1 (en) * | 2006-08-30 | 2009-01-22 | Parsons C Lowell | Methods for detecting and treating interstitial cystitis |
DE102006060953A1 (de) * | 2006-12-12 | 2008-08-07 | Farco-Pharma Gmbh | Pharmazeutische Zubereitung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes |
WO2008144485A2 (en) * | 2007-05-18 | 2008-11-27 | University Of Maryland, Baltimore | Inhibition of palmitoyl acyl transferase expression and/or activity for the regulation of antiproliferative factor activity |
US9849086B2 (en) * | 2012-03-19 | 2017-12-26 | Nanologix Research, Inc. | Method and composition for treating cystitis |
CN107108761B (zh) * | 2015-01-09 | 2020-06-30 | 生化学工业株式会社 | 硫酸软骨素衍生物和膀胱疾病处置剂 |
EP3512561A4 (en) | 2016-09-16 | 2020-10-07 | Glycologix, LLC | SULFATED GLYCOSAMINOGLYCAN BIOMATERIALS AS PROTEOGLYCAN MIMETICS |
DE202017103288U1 (de) | 2017-05-12 | 2018-05-16 | Farco-Pharma Gmbh | Zusammensetzung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes in Form einer hochdosierten Wirkstoffkombination |
EP3400950B1 (de) | 2017-05-12 | 2019-11-13 | Farco-Pharma GmbH | Blaseninstillationszusammensetzung enthaltend chondoitinsulfat (20 mg/ml), hyaluronsäure (16 mg/ml) und phosphatpuffer (ph 6,1 bis 7,9) mit erhöhter lagerstabiliät zur behandlung von cystitis |
DE202017103289U1 (de) | 2017-05-12 | 2018-05-16 | Farco-Pharma Gmbh | Zusammensetzung für die Behandlung entzündlicher Erkrankungen des Urogenitaltraktes in Form einer Wirkstoffkombination |
ES2775673T3 (es) * | 2017-05-12 | 2020-07-27 | Farco Gmbh | Composición para el tratamiento de enfermedades inflamatorias del tracto urogenital que contiene sulfato de condonita (4,5 mg/ml), ácido hialurónico (16 mg/ml) y tampón de fosfato (pH 6,1 a 7,9) con mayor estabilidad de almacenamiento para tratar la cistitis |
EP3415163B1 (de) | 2017-06-13 | 2023-02-22 | Farco-Pharma GmbH | Zusammensetzung mit lokalanästhetischer wirkung und deren verwendung |
DE202017104675U1 (de) | 2017-06-13 | 2018-06-14 | Farco-Pharma Gmbh | Zusammensetzung mit lokalanästhetischer Wirkung und deren Verwendung |
WO2022246405A1 (en) * | 2021-05-18 | 2022-11-24 | Karuna Therapeutics, Inc. | Methods for treating central nervous system disorders with muscarinic receptor activation and antipsychotics |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
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US4971955A (en) * | 1981-03-02 | 1990-11-20 | Soll David B | Protection of human and animal cells during surgical trauma |
FR2535324A1 (fr) * | 1982-10-27 | 1984-05-04 | Choay Sa | Station perfectionnee pour l'epuration d'eaux usees |
CA1187798A (en) | 1982-03-24 | 1985-05-28 | David B. Soll | Protection of cells |
AU555747B2 (en) | 1983-08-09 | 1986-10-09 | Cilco Inc. | Chondroitin sulfate and sodium hyaluronate composition |
US4886786A (en) * | 1985-08-01 | 1989-12-12 | Lindstrom Richard L | Additive for irrigation solution or surgical solution |
EP0240098A3 (en) * | 1986-04-04 | 1989-05-10 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Oligo and polysaccharides for the treatment of diseases caused by retroviruses |
IT1213384B (it) * | 1986-11-24 | 1989-12-20 | Lab Derivati Organici Mediolan | Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare. |
US5541166A (en) * | 1987-01-23 | 1996-07-30 | The Australian National University | Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity |
US5037810A (en) * | 1987-03-17 | 1991-08-06 | Saliba Jr Michael J | Medical application for heparin and related molecules |
IT1217458B (it) * | 1988-05-02 | 1990-03-22 | Crinos Ind Farmacoriologica S | Sulfoamino derivati di condroitin solfati,del dermatan solfato e dell' acido ialuronico e loro proprieta' farmacologiche |
WO1991006303A1 (en) | 1989-10-27 | 1991-05-16 | Case Western Reserve University | Inhibition of cell growth by keratan sulfate, chondroitin sulfate, dermatan sulfate and other glycans |
US5158940A (en) * | 1990-02-14 | 1992-10-27 | The United States Government As Represented By The Secretary, Dhhs | Use of suramin to treat rheumatologic diseases |
CA2020199C (en) | 1990-06-29 | 2002-08-20 | Daniel Bar-Shalom | Uses of sulphated sugars |
DE4021066A1 (de) | 1990-07-03 | 1992-01-09 | Hoechst Ag | Langzeitprophylaxe gegen erkrankungen, die durch viren oder durch unkonventionelle viren verursacht werden |
CA2060223C (en) | 1991-02-12 | 1999-07-20 | Clarence C. Lee | Injectable medical lubricating fluid composition and method of use |
IT1245907B (it) | 1991-05-17 | 1994-10-25 | Alfa Wassermann Spa | Uso dei glicosaminoglicani nel trattamento della nefropatia diabetica e della neuropatia diabetica. |
US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
IL102758A (en) | 1991-08-23 | 1997-03-18 | Akzo Nv | Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them |
EP0571597A4 (en) | 1991-11-15 | 1994-06-01 | Arthro Res & Dev Corp | Method for treatment of acute and chronic painful arthropathic conditions in human and other mammals |
EP0636631A1 (en) * | 1992-04-17 | 1995-02-01 | Seikagaku Corporation | Platinum complex and antineoplastic agent |
WO1994000135A1 (en) | 1992-06-30 | 1994-01-06 | Shapiro Howard K | Composition containing amine and amine-related derivatives of benzoic acid and uses therefor including treating inflammatory diseases |
IT1264530B (it) * | 1992-07-31 | 1996-10-02 | Crinos Industria Farmaco | Impiego dei polisaccaridi nelle neuropatie atrofico degenerative |
US6492349B1 (en) * | 1993-03-31 | 2002-12-10 | Nutramax Laboratories, Inc. | Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue |
NZ260933A (en) | 1993-07-16 | 1996-07-26 | Hercules Inc | Cation-complexed polysaccharides; use in foods and pharmaceuticals |
CA2130295A1 (en) | 1993-08-26 | 1995-02-27 | Richard A. Berg | Ionically crosslinked glycosaminoglycan gels for soft tissue augmentation and drug delivery |
AU698881B2 (en) | 1994-05-11 | 1998-11-12 | Howard K. Shapiro | Compositions for treatment of chronic inflammatory diseases |
IN181358B (es) | 1995-02-14 | 1998-05-30 | Bioniche Inc | |
AUPN261895A0 (en) * | 1995-04-28 | 1995-05-18 | Australian National University, The | Preparation and use of sulfated oligosaccharides |
CN1196734A (zh) * | 1995-09-19 | 1998-10-21 | 生化学工业株式会社 | 消炎药 |
CA2217134A1 (en) | 1996-10-09 | 1998-04-09 | Sumitomo Pharmaceuticals Co., Ltd. | Sustained release formulation |
US6689748B1 (en) * | 1998-04-08 | 2004-02-10 | Theoharis C. Theoharides | Method of treating mast cell activation-induced diseases with a proteoglycan |
US20030232100A1 (en) * | 1998-04-08 | 2003-12-18 | Theoharides Theoharis C. | Compositions for treatment of diseases arising from secretion of mast cell biochemicals |
CA2269260C (en) | 1999-04-16 | 2002-12-31 | Stellar International Inc. | Treatment of cystitis with chondroitin sulfate |
US6083933A (en) * | 1999-04-19 | 2000-07-04 | Stellar International Inc. | Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution |
JP2001213784A (ja) * | 2000-02-03 | 2001-08-07 | Teisan Seiyaku Kk | 乳牛の***炎治療剤 |
EP1311276A4 (en) * | 2000-07-31 | 2007-09-12 | Dermal Res Lab Inc | METHODS FOR THE PREVENTION OR TREATMENT OF DISEASES AND CONDITIONS USING COMPLEX CARBOHYDRATES |
US7485629B2 (en) * | 2002-10-16 | 2009-02-03 | Arthrodynamic Technologies, Animal Health Division, Inc. | Composition and method for treatment of joint damage |
US6979679B2 (en) * | 2002-10-16 | 2005-12-27 | Marcum Frank D | Composition and method for treatment and prevention of traumatic synovitis and damage to articular cartilage |
US7504387B2 (en) * | 2002-10-16 | 2009-03-17 | Arthrodynamic Technologies, Animal Health Division, Inc. | Glycosaminoglycan composition and method for treatment and prevention of interstitial cystitis |
US20040161476A1 (en) | 2003-02-19 | 2004-08-19 | Hahn Sungtack Samuel | Cystitis treatment with high dose chondroitin sulfate |
-
2003
- 2003-02-19 US US10/367,970 patent/US20040161476A1/en not_active Abandoned
-
2004
- 2004-02-18 WO PCT/CA2004/000244 patent/WO2004073584A2/en active Application Filing
- 2004-02-18 ES ES04711966.4T patent/ES2527664T3/es not_active Expired - Lifetime
- 2004-02-18 US US10/546,511 patent/US7772210B2/en active Active
- 2004-02-18 JP JP2006501424A patent/JP4778888B2/ja not_active Expired - Fee Related
- 2004-02-18 PT PT47119664T patent/PT1603578E/pt unknown
- 2004-02-18 AU AU2004212650A patent/AU2004212650B2/en not_active Ceased
- 2004-02-18 DK DK04711966.4T patent/DK1603578T3/en active
- 2004-02-18 EP EP14189577.1A patent/EP2857024A1/en not_active Ceased
- 2004-02-18 DE DE14189577.1T patent/DE14189577T9/de active Active
- 2004-02-18 SI SI200432205T patent/SI1603578T1/sl unknown
- 2004-02-18 CA CA2515512A patent/CA2515512C/en not_active Expired - Lifetime
- 2004-02-18 CN CN2004800064671A patent/CN1758920B/zh not_active Expired - Fee Related
- 2004-02-18 EP EP04711966.4A patent/EP1603578B1/en not_active Revoked
-
2005
- 2005-08-16 IL IL170309A patent/IL170309A/en not_active IP Right Cessation
-
2006
- 2006-06-12 HK HK06106699.5A patent/HK1085136A1/xx not_active IP Right Cessation
-
2010
- 2010-07-21 US US12/804,478 patent/US8084441B2/en not_active Expired - Fee Related
-
2011
- 2011-11-08 US US13/373,226 patent/US8334276B2/en not_active Expired - Lifetime
-
2012
- 2012-12-17 US US13/717,551 patent/US8778908B2/en not_active Expired - Lifetime
-
2014
- 2014-12-15 CY CY20141101043T patent/CY1116069T1/el unknown
-
2015
- 2015-05-13 IL IL238811A patent/IL238811A/en not_active IP Right Cessation
- 2015-10-05 HK HK15109720.1A patent/HK1209037A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
IL170309A (en) | 2015-11-30 |
EP1603578B1 (en) | 2014-10-29 |
US8084441B2 (en) | 2011-12-27 |
US20100292182A1 (en) | 2010-11-18 |
CA2515512A1 (en) | 2004-09-02 |
SI1603578T1 (sl) | 2015-04-30 |
AU2004212650B2 (en) | 2009-07-23 |
HK1209037A1 (en) | 2016-03-24 |
WO2004073584A3 (en) | 2005-01-27 |
IL238811A0 (en) | 2015-06-30 |
US8334276B2 (en) | 2012-12-18 |
DE14189577T9 (de) | 2020-12-10 |
CN1758920B (zh) | 2010-05-26 |
US20130143839A1 (en) | 2013-06-06 |
US8778908B2 (en) | 2014-07-15 |
WO2004073584A2 (en) | 2004-09-02 |
CY1116069T1 (el) | 2017-02-08 |
EP1603578A2 (en) | 2005-12-14 |
DK1603578T3 (en) | 2015-01-19 |
HK1085136A1 (en) | 2006-08-18 |
JP2006517928A (ja) | 2006-08-03 |
US20120058969A1 (en) | 2012-03-08 |
JP4778888B2 (ja) | 2011-09-21 |
AU2004212650A1 (en) | 2004-09-02 |
US20060194757A1 (en) | 2006-08-31 |
CA2515512C (en) | 2012-07-10 |
US20040161476A1 (en) | 2004-08-19 |
PT1603578E (pt) | 2014-12-11 |
DE14189577T1 (de) | 2019-10-17 |
US7772210B2 (en) | 2010-08-10 |
CN1758920A (zh) | 2006-04-12 |
IL238811A (en) | 2017-03-30 |
EP2857024A1 (en) | 2015-04-08 |
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