Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AGfiledCriticalCiba Geigy AG
Publication of ES248290A1publicationCriticalpatent/ES248290A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
Process for obtaining new thiazole compounds, characterized in that the 2-amino-4- [lower alkyl-pyridyl- (2 ')] -thiazoles, of the formula ** (See formula) ** where R represents a lower alkyl residue with 1-6 carbon atoms, its N-acyl derivatives and its salts, are obtained by: a) reacting an alkyl-2-acetyl-pyridine, which in the acetyl moiety carries a reactable substituent, with thiourea and an N-acylthiourea; b) reacting an alkyl-2-acetyl-pyridine with thiourea, an N-acylthiourea and an oxidizing agent, and c) in 2-X-4- [lower alkyl- pyridyl- (2 ')] - thiazoles where X means a moiety transformable into a free or acylated amine group, X is transformed into the acylated or free amine group, where the expression "lower alkyl" means alkyl moieties with 1-6 carbon atoms, and if desired, the compounds obtained with an The free amine group is acylated and the N-acyl compounds obtained are saponified, if desired, the bases obtained are transformed into their salts and the salts obtained in the bases. (Machine-translation by Google Translate, not legally binding)
ES0248290A1958-04-141959-03-28Procedure for the obtaining of new tiazolic compounds (Machine-translation by Google Translate, not legally binding)
ExpiredES248290A1
(en)
Procedure for the preparation of N-substituted piperidine derivatives and their use as stabilizers. (Machine-translation by Google Translate, not legally binding)
Procedure for preparing fluoracilaminotriclorometilmetano derivatives of insecticides and acaricides effects. (Machine-translation by Google Translate, not legally binding)
Procedure for obtaining the new N- (2-chlorine-ethyl) -N- (5-nitro-tiazolil-2) -urea and its salts (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of n, n - (tetrahydrofurfurilmalonil) -5,6-dihydro-benzo (c) cinoline and of derivatives of the same (Machine-translation by Google Translate, not legally binding)