ES2466065B1 - Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos - Google Patents

Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos Download PDF

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Publication number
ES2466065B1
ES2466065B1 ES201231908A ES201231908A ES2466065B1 ES 2466065 B1 ES2466065 B1 ES 2466065B1 ES 201231908 A ES201231908 A ES 201231908A ES 201231908 A ES201231908 A ES 201231908A ES 2466065 B1 ES2466065 B1 ES 2466065B1
Authority
ES
Spain
Prior art keywords
stimuli
biocompatible
polyurethane
modification
transfer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES201231908A
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English (en)
Other versions
ES2466065A1 (es
Inventor
Franklin MUÑOZ MUÑOZ
Emilio BUCIO CARRILLO
Carmen ÁLVAREZ LORENZO
Ángel CONCHEIRO NINE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidade de Santiago de Compostela
Universidad Nacional Autonoma de Mexico
Original Assignee
Universidade de Santiago de Compostela
Universidad Nacional Autonoma de Mexico
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidade de Santiago de Compostela, Universidad Nacional Autonoma de Mexico filed Critical Universidade de Santiago de Compostela
Priority to ES201231908A priority Critical patent/ES2466065B1/es
Priority to MX2013014436A priority patent/MX358608B/es
Publication of ES2466065A1 publication Critical patent/ES2466065A1/es
Application granted granted Critical
Publication of ES2466065B1 publication Critical patent/ES2466065B1/es
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/08—Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of nitriles
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials For Medical Uses (AREA)
  • Polyurethanes Or Polyureas (AREA)

Abstract

Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos. La invención se refiere a poliuretanos en forma de películas, láminas o catéteres modificados, por medio de radiación gamma ({ga}), con injertos de redes poliméricas interpenetrantes (IPNs) y semi-interprenetrates (s-IPNs) sensibles a la temperatura y al pH, que presenten una alta biocompatibilidad, para su aplicación como sistemas implantables de liberación local de fármacos útiles en la prevención y el tratamiento de estados patológicos o fisiológicos asociados al uso de productos sanitarios, en la elaboración de sistemas de liberación tópica, transdérmica o transmucosal de medicamentos o sustancias activas y en la preparación de cosméticos.

Description

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Claims (1)

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    imagen2
ES201231908A 2012-12-07 2012-12-07 Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos Expired - Fee Related ES2466065B1 (es)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ES201231908A ES2466065B1 (es) 2012-12-07 2012-12-07 Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos
MX2013014436A MX358608B (es) 2012-12-07 2013-12-06 Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201231908A ES2466065B1 (es) 2012-12-07 2012-12-07 Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos

Publications (2)

Publication Number Publication Date
ES2466065A1 ES2466065A1 (es) 2014-06-09
ES2466065B1 true ES2466065B1 (es) 2015-03-31

Family

ID=50843169

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201231908A Expired - Fee Related ES2466065B1 (es) 2012-12-07 2012-12-07 Modificación de poliuretano con polímeros sensibles a estímulos biocompatibles para carga y cesión de fármacos

Country Status (2)

Country Link
ES (1) ES2466065B1 (es)
MX (1) MX358608B (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2578133B2 (ja) * 1987-10-15 1997-02-05 サンスター技研株式会社 ポリウレタン接着剤
WO2010005992A1 (en) * 2008-07-07 2010-01-14 Biomimedica, Inc. Hydrophilic interpenetrating polymer networks derived from hydrophobic polymers
EP2323670A4 (en) * 2008-08-05 2013-12-25 Biomimedica Inc POLYURETHANE-GEPPROPFTE HYDROGELE

Also Published As

Publication number Publication date
ES2466065A1 (es) 2014-06-09
MX2013014436A (es) 2015-04-01
MX358608B (es) 2018-08-21

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