ES2200678B1 - Uso de la proteina mal como marcador tumoral. - Google Patents
Uso de la proteina mal como marcador tumoral.Info
- Publication number
- ES2200678B1 ES2200678B1 ES200200615A ES200200615A ES2200678B1 ES 2200678 B1 ES2200678 B1 ES 2200678B1 ES 200200615 A ES200200615 A ES 200200615A ES 200200615 A ES200200615 A ES 200200615A ES 2200678 B1 ES2200678 B1 ES 2200678B1
- Authority
- ES
- Spain
- Prior art keywords
- protein
- marker
- tumor marker
- bad protein
- bad
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
Abstract
Uso de la proteína MAL como marcador tumoral. La invención presente presenta la utilización de la proteína mal como un nuevo marcador y diana molecular en tumores epiteliales y otras patologías humanas. En concreto forma parte de la presente invención el uso de la detección de la proteína MAL como marcador con fines diagnósticos o pronósticos para tumores u otras patologías que afecten a células epiteliales, linfocitos T, mastocitos, células formadora de mielina o otros tipos celulares que normalmente expresen la proteína MAL.
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200200615A ES2200678B1 (es) | 2002-03-14 | 2002-03-14 | Uso de la proteina mal como marcador tumoral. |
CA002476767A CA2476767A1 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
RU2004129773/15A RU2004129773A (ru) | 2002-03-14 | 2003-03-14 | Использование белка mal в качестве опухолевого маркера |
KR10-2004-7014489A KR20040105771A (ko) | 2002-03-14 | 2003-03-14 | Mal 단백질을 종양 표지자로 사용하는 방법 |
EP03712142A EP1930728A1 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
JP2003575121A JP2005520135A (ja) | 2002-03-14 | 2003-03-14 | 腫瘍マーカーとしてのmalタンパク質の使用 |
AU2003216926A AU2003216926A1 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
PCT/ES2003/000119 WO2003076948A1 (es) | 2002-03-14 | 2003-03-14 | Uso de la proteina mal como marcador tumoral |
IL16357803A IL163578A0 (en) | 2002-03-14 | 2003-03-14 | Use of the mal protein as a tumour marker |
CNA038057565A CN1643380A (zh) | 2002-03-14 | 2003-03-14 | 将mal蛋白作为肿瘤标记的应用 |
MXPA04008962A MXPA04008962A (es) | 2002-03-14 | 2003-03-14 | Uso de la proteina mal como marcador tumoral. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200200615A ES2200678B1 (es) | 2002-03-14 | 2002-03-14 | Uso de la proteina mal como marcador tumoral. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2200678A1 ES2200678A1 (es) | 2004-03-01 |
ES2200678B1 true ES2200678B1 (es) | 2005-06-01 |
Family
ID=27799028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200200615A Expired - Fee Related ES2200678B1 (es) | 2002-03-14 | 2002-03-14 | Uso de la proteina mal como marcador tumoral. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1930728A1 (es) |
JP (1) | JP2005520135A (es) |
KR (1) | KR20040105771A (es) |
CN (1) | CN1643380A (es) |
AU (1) | AU2003216926A1 (es) |
CA (1) | CA2476767A1 (es) |
ES (1) | ES2200678B1 (es) |
IL (1) | IL163578A0 (es) |
MX (1) | MXPA04008962A (es) |
RU (1) | RU2004129773A (es) |
WO (1) | WO2003076948A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20200037366A (ko) | 2017-08-11 | 2020-04-08 | 제넨테크, 인크. | 항-cd8 항체 및 이의 용도 |
EP3903805A4 (en) * | 2018-12-28 | 2022-09-14 | Neogentc Corp. (Convergence Innovation Building, Asan Institute for Life Sciences, Pungnap-dong) | COMPOSITION OF OR ENHANCEMENT OF ANTI-CANCER OR IMMUNOSTIMULATING ACTIVITY COMPRISING A MAL-EXPRESSED STEM CELL-LIKE MEMORY T CELL AS AN ACTIVE INGREDIENT |
WO2020139027A1 (ko) * | 2018-12-28 | 2020-07-02 | 울산대학교 산학협력단 | Mal이 발현된 줄기세포 유사 기억 t 세포를 유효성분으로 포함하는 면역증강 또는 항암활성 증진용 조성물 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1248801A4 (en) * | 2000-01-18 | 2003-08-27 | Human Genome Sciences Inc | POLYNUCLEOTIDES, POLYPEPTIDES AND HUMAN ANTIBODIES |
-
2002
- 2002-03-14 ES ES200200615A patent/ES2200678B1/es not_active Expired - Fee Related
-
2003
- 2003-03-14 WO PCT/ES2003/000119 patent/WO2003076948A1/es active Application Filing
- 2003-03-14 AU AU2003216926A patent/AU2003216926A1/en not_active Abandoned
- 2003-03-14 CA CA002476767A patent/CA2476767A1/en not_active Abandoned
- 2003-03-14 MX MXPA04008962A patent/MXPA04008962A/es not_active Application Discontinuation
- 2003-03-14 IL IL16357803A patent/IL163578A0/xx unknown
- 2003-03-14 RU RU2004129773/15A patent/RU2004129773A/ru not_active Application Discontinuation
- 2003-03-14 JP JP2003575121A patent/JP2005520135A/ja active Pending
- 2003-03-14 CN CNA038057565A patent/CN1643380A/zh active Pending
- 2003-03-14 EP EP03712142A patent/EP1930728A1/en not_active Withdrawn
- 2003-03-14 KR KR10-2004-7014489A patent/KR20040105771A/ko not_active Application Discontinuation
Non-Patent Citations (4)
Also Published As
Publication number | Publication date |
---|---|
MXPA04008962A (es) | 2005-06-03 |
KR20040105771A (ko) | 2004-12-16 |
EP1930728A1 (en) | 2008-06-11 |
RU2004129773A (ru) | 2005-05-10 |
CN1643380A (zh) | 2005-07-20 |
WO2003076948A1 (es) | 2003-09-18 |
CA2476767A1 (en) | 2003-09-18 |
AU2003216926A1 (en) | 2003-09-22 |
JP2005520135A (ja) | 2005-07-07 |
IL163578A0 (en) | 2005-12-18 |
ES2200678A1 (es) | 2004-03-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GB2561940A (en) | System and method for protein corona sensor array for early detection of diseases | |
CL2013000951A1 (es) | Anticuerpo que presenta alta afinidad con proteinas tau solubles e insoluble y modula los niveles tau solubles e insolubles; peptido de union; composicion farmaceutica que comprende el peptido o proteina de union, un anticuerpo o polinucleotido; uso para tratar enfermedad neurodegenerativa. | |
MX2010009766A (es) | Ensayo de proteasa. | |
ATE490465T1 (de) | Diagnose- und prognoseverfahren von blasenkrebs. | |
EP2611941A4 (en) | GENESIS OF CANCER DIAGNOSIS AND PROGNOSIS | |
EA201400710A1 (ru) | Способы детекции признаков заболеваний или состояний в жидкостях организма | |
PL2211180T3 (pl) | Zastosowanie białka SATB2 jako markera do rozróżniania nowotworów jelita grubego od innych nowotworów | |
ATE527385T1 (de) | Mit tumoren assoziierte genetische variationen | |
EP2560006A3 (en) | Biomarkers for prostate cancer and methods using the same | |
HK1115636A1 (en) | Use of cyfra 21-1 as a marker for colorectal cancer cyfra 21-1 | |
WO2007149476A3 (en) | Assays for non-apoptotic cell death and uses thereof | |
WO2007106900A3 (en) | Quantitative molecular probes | |
WO2008137838A3 (en) | Interferon alpha-induced pharmacodynamic markers | |
CY1119568T1 (el) | Περιοχη δεσμευσης της βακτηριακης ατρ συνθασης | |
WO2007079284A3 (en) | Lung cancer diagnostic assay | |
CR11504A (es) | Deteccion mejorada de la expresion de mage-a | |
WO2009126969A3 (en) | Biomarkers for endometrial disease | |
Tsaur et al. | sE-cadherin serves as a diagnostic and predictive parameter in prostate cancer patients | |
DE50207866D1 (de) | Verwendung löslicher cytokeratin-1-fragmente in diagnostik | |
WO2004062487A3 (en) | Methods of detecting gene expression in normal and cancerous cells | |
WO2007020522A3 (en) | Protein markers for diagnosing of colorectal cancer and use of said markers as drug targets for the treatment of said cancer type | |
WO2012083274A3 (en) | Methods for diagnosis, prognosis and methods of treatment | |
HK1136873A1 (en) | Use of nnmt as a marker for lung cancer | |
WO2006099537A3 (en) | The use of antibody-surrogate antigen systems for detection of analytes | |
ES2200678B1 (es) | Uso de la proteina mal como marcador tumoral. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 20040301 Kind code of ref document: A1 |
|
FG2A | Definitive protection |
Ref document number: 2200678B1 Country of ref document: ES |
|
FD1A | Patent lapsed |
Effective date: 20100312 |