ES2196918T3 - Sistema de suministro osmotico dotado de piston con economia de espacio.. - Google Patents

Sistema de suministro osmotico dotado de piston con economia de espacio..

Info

Publication number
ES2196918T3
ES2196918T3 ES99967575T ES99967575T ES2196918T3 ES 2196918 T3 ES2196918 T3 ES 2196918T3 ES 99967575 T ES99967575 T ES 99967575T ES 99967575 T ES99967575 T ES 99967575T ES 2196918 T3 ES2196918 T3 ES 2196918T3
Authority
ES
Spain
Prior art keywords
piston
osmotic
capsule
supply system
system equipped
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99967575T
Other languages
English (en)
Inventor
Bonnie J Eckenhoff
Felix Theeuwes
James B Di Eckenhoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ES2196918T3 publication Critical patent/ES2196918T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • External Artificial Organs (AREA)

Abstract

Sistema de suministro osmótico, que comprende: una cápsula, estando dotada dicha cápsula de un interior para el alojamiento de un agente beneficioso, presentando dicho interior una superficie interior; un agente osmótico situado en dicho interior; un cuerpo semipermeable en comunicación de líquido con dicha cápsula para permitir que un líquido se infiltre a través de dicho cuerpo semipermeable hasta dicho agente osmótico; y un pistón situado dentro de dicho interior de dicha cápsula, el cual puede desplazarse con respecto a dicha superficie interior de dicha cápsula, determinando una obturación móvil con dicha superficie interior de dicha cápsula que separa dicho agente osmótico de dicho agente beneficioso, y presentando un rebaje que recibe por lo menos una parte de dicho agente osmótico, dicho agente osmótico, que se encuentra situado entre dicho pistón y dicho cuerpo semipermeable, tiene por objeto embeber líquido de un ambiente envolvente a través de dicho cuerpo semipermeable para provocar que dicho pistón se desplace, produciendo a su vez una descarga del agente beneficioso de dicha cápsula.
ES99967575T 1998-12-31 1999-12-21 Sistema de suministro osmotico dotado de piston con economia de espacio.. Expired - Lifetime ES2196918T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11454898P 1998-12-31 1998-12-31

Publications (1)

Publication Number Publication Date
ES2196918T3 true ES2196918T3 (es) 2003-12-16

Family

ID=22355938

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99967575T Expired - Lifetime ES2196918T3 (es) 1998-12-31 1999-12-21 Sistema de suministro osmotico dotado de piston con economia de espacio..

Country Status (13)

Country Link
US (5) US6544252B1 (es)
EP (1) EP1140014B1 (es)
JP (2) JP4383674B2 (es)
AT (1) ATE234603T1 (es)
AU (1) AU771132B2 (es)
CA (1) CA2356860C (es)
DE (1) DE69906132T2 (es)
DK (1) DK1140014T3 (es)
ES (1) ES2196918T3 (es)
HK (1) HK1040916B (es)
NZ (1) NZ512671A (es)
PT (1) PT1140014E (es)
WO (1) WO2000040218A2 (es)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
DK1140014T3 (da) * 1998-12-31 2003-07-14 Alza Corp Osmotisk afgivelsessystem med pladsbesparende stempel
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
US7258869B1 (en) * 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
KR100734187B1 (ko) * 1999-12-21 2007-07-02 알자 코포레이션 삼투성 장치용 밸브
US7163688B2 (en) * 2001-06-22 2007-01-16 Alza Corporation Osmotic implant with membrane and membrane retention means
CN1668279A (zh) * 2002-06-17 2005-09-14 阿尔萨公司 具有包含分散在液体载体中的渗透物质的早期零级推动力动力***的渗透递送体系
CA2508124A1 (en) * 2002-12-19 2004-07-08 Alza Corporation Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
US7731947B2 (en) 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
KR20050120767A (ko) * 2003-03-31 2005-12-23 알자 코포레이션 삼투성 전달 시스템 및 삼투성 전달 시스템의 기동 시간감소 방법
CN100548411C (zh) * 2003-03-31 2009-10-14 精达制药公司 设置有内部压力释放部件的渗透泵
US8257963B2 (en) * 2007-06-01 2012-09-04 Depuy Mitek, Inc. Chondrocyte container and method of use
RU2006119632A (ru) * 2003-11-06 2007-12-20 Алза Корпорейшн (Us) Модульный ограничитель скорости впитывания для использования с имплантируемым осмотическим насосом
WO2005070445A2 (en) * 2004-01-13 2005-08-04 Vasogenix Pharmaceuticals, Inc. Methods for treating acute myocardial infarction by calcitonin gene related peptide and compositions containing the same
CA2552757A1 (en) * 2004-01-13 2005-08-04 Vasogenix Pharmaceuticals, Inc. Methods of using cgrp for cardiovascular and renal indications
US7976847B2 (en) * 2004-01-13 2011-07-12 Vasogenix Pharmaceuticals, Inc. Controlled release CGRP delivery composition for cardiovascular and renal indications
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
JP2008528698A (ja) * 2005-02-03 2008-07-31 インターシア セラピューティクス，インコーポレイティド 埋め込み可能なインターフェロン含有デバイス
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) * 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US7959938B2 (en) * 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
US20070025869A1 (en) * 2005-07-15 2007-02-01 Gordon John H Fluid Delivery Device
US20070163968A1 (en) * 2006-01-17 2007-07-19 Johnsondiversey, Inc. Method and apparatus for providing treatment chemicals to process water systems
DE602007009377D1 (de) 2006-05-30 2010-11-04 Intarcia Therapeutics Inc Zweiteiliger flussmodulator mit einem internen kanal für ein osmotisches ausgabesystem
US8321025B2 (en) 2006-07-31 2012-11-27 Cranial Medical Systems, Inc. Lead and methods for brain monitoring and modulation
US7583999B2 (en) * 2006-07-31 2009-09-01 Cranial Medical Systems, Inc. Multi-channel connector for brain stimulation system
US7682356B2 (en) 2006-08-09 2010-03-23 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies for use therein
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
US20080147186A1 (en) * 2006-12-14 2008-06-19 Joshi Ashok V Electrochemical Implant For Delivering Beneficial Agents
JP5351884B2 (ja) 2007-04-23 2013-11-27 インターシア セラピューティクス，インコーポレイティド インスリン分泌促進性ペプチドの懸濁製剤及び使用
CA2726861C (en) 2008-02-13 2014-05-27 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
AU2009303905B2 (en) * 2008-10-15 2015-01-22 Intarcia Therapeutics, Inc. Highly concentrated drug particles, formulations, suspensions and uses thereof
HUE035862T2 (en) 2009-09-28 2018-05-28 Intarcia Therapeutics Inc Rapid development and / or completion of substantially steady-state drug delivery
JP2011104346A (ja) * 2009-10-22 2011-06-02 Neocel:Kk 人工透析用具
NZ599524A (en) 2009-11-09 2014-04-30 Spotlight Technology Partners Llc Polysaccharide based hydrogels
EP2498764B1 (en) 2009-11-09 2017-09-06 Spotlight Technology Partners LLC Fragmented hydrogels
SG188317A1 (en) 2010-08-30 2013-04-30 Sinusys Corp Devices for dilating a paranasal sinus opening and for treating sinusitis
US8583237B2 (en) 2010-09-13 2013-11-12 Cranial Medical Systems, Inc. Devices and methods for tissue modulation and monitoring
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
JP2015509786A (ja) 2012-02-29 2015-04-02 サイナシス コーポレーション 副鼻腔開口部を拡張して副鼻腔炎を治療するためのデバイスおよび方法
US9687263B2 (en) 2013-05-30 2017-06-27 SinuSys Corporation Devices and methods for inserting a sinus dilator
US9757330B2 (en) 2013-10-18 2017-09-12 Industrial Technology Research Institute Recipe for in-situ gel, and implant, drug delivery system formed thereby
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
ES2968262T3 (es) 2015-06-03 2024-05-08 I2O Therapeutics Inc Sistemas de colocación de implantes
EP3370705B1 (en) 2015-11-05 2022-03-09 The General Hospital Corporation Intrathecal delivery of nucleic acid sequences encoding abcd1 for treatment of adrenomyeloneuropathy
WO2017200943A1 (en) 2016-05-16 2017-11-23 Intarcia Therapeutics, Inc. Glucagon-receptor selective polypeptides and methods of use thereof
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
KR20190086460A (ko) 2016-10-20 2019-07-22 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 신경보호 폴리펩티드를 중추 신경계에 전달하는 방법
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
WO2018165462A1 (en) 2017-03-08 2018-09-13 Intarcia Therapeutics, Inc Apparatus and methods for administration of a nauseogenic compound from a drug delivery device
CN108211107B (zh) * 2018-03-01 2023-08-15 中南民族大学 一种针对穴位持续给药的压力可控式微泡贴及制备方法
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
WO2020077129A1 (en) 2018-10-11 2020-04-16 Intarcia Therapeutics, Inc. Human amylin analog polypeptides and methods of use
RO134455A0 (ro) * 2019-11-27 2020-09-30 Ştefan-Sorin Aramă Dispozitiv medical de temporizare

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3995632A (en) * 1973-05-04 1976-12-07 Alza Corporation Osmotic dispenser
US3862042A (en) * 1974-02-27 1975-01-21 Becton Dickinson Co Serum/plasma separator - piston with red-cell trapping surfaces
US4074715A (en) * 1976-11-01 1978-02-21 Becton, Dickinson And Company Syringe plunger
US4619652A (en) 1982-12-23 1986-10-28 Alza Corporation Dosage form for use in a body mounted pump
US4595583A (en) * 1984-03-19 1986-06-17 Alza Corporation Delivery system controlled administration of beneficial agent to ruminants
US4624945A (en) * 1984-03-19 1986-11-25 Alza Corporation Dispensing system with means for increasing delivery of beneficial agent from the system
US4838862A (en) * 1986-08-04 1989-06-13 Pharmetrix Corp. Portable controlled release osmotic infusion device
US4874388A (en) 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5062841A (en) 1988-08-12 1991-11-05 The Regents Of The University Of California Implantable, self-regulating mechanochemical insulin pump
US4929233A (en) * 1988-08-26 1990-05-29 Alza Corporation Implantable fluid imbibing pump with improved closure
US4969884A (en) * 1988-12-28 1990-11-13 Alza Corporation Osmotically driven syringe
US5234424A (en) 1988-12-28 1993-08-10 Alza Corporation Osmotically driven syringe
GB9027422D0 (en) * 1990-12-18 1991-02-06 Scras Osmotically driven infusion device
US5236707A (en) * 1991-11-08 1993-08-17 Dallas Biotherapeutics, Inc. Stabilization of human interferon
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5639477A (en) 1993-06-23 1997-06-17 Alza Corporation Ruminal drug delivery device
CZ300994B6 (cs) * 1996-02-02 2009-10-07 Alza Corporation Implantabilní zarízení pro dodávání aktivního cinidla
ZA981610B (en) 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
AU1828599A (en) * 1997-12-29 1999-07-19 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
DE69817621T2 (de) * 1997-12-31 2004-03-25 Alza Corp., Mountain View Osmotisches Abgabesystem für ein wirksames Mittel
DK1140014T3 (da) * 1998-12-31 2003-07-14 Alza Corp Osmotisk afgivelsessystem med pladsbesparende stempel

Also Published As

Publication number Publication date
AU2383600A (en) 2000-07-24
US20070203476A1 (en) 2007-08-30
US20030139732A1 (en) 2003-07-24
US6544252B1 (en) 2003-04-08
HK1040916A1 (en) 2002-06-28
DE69906132T2 (de) 2003-12-18
NZ512671A (en) 2003-12-19
HK1040916B (zh) 2003-10-03
WO2000040218A2 (en) 2000-07-13
US7235068B2 (en) 2007-06-26
DK1140014T3 (da) 2003-07-14
JP2009183737A (ja) 2009-08-20
PT1140014E (pt) 2003-07-31
US6872201B2 (en) 2005-03-29
EP1140014B1 (en) 2003-03-19
CA2356860C (en) 2006-11-07
JP4383674B2 (ja) 2009-12-16
AU771132B2 (en) 2004-03-11
ATE234603T1 (de) 2003-04-15
DE69906132D1 (de) 2003-04-24
CA2356860A1 (en) 2000-07-13
US20060129139A1 (en) 2006-06-15
US6997922B2 (en) 2006-02-14
JP2002534164A (ja) 2002-10-15
WO2000040218A3 (en) 2000-11-09
EP1140014A2 (en) 2001-10-10
US20050085797A1 (en) 2005-04-21

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