ES2194867T3 - Composiciones farmaceuticas para la administracion intranasal de apomorfina. - Google Patents

Composiciones farmaceuticas para la administracion intranasal de apomorfina.

Info

Publication number
ES2194867T3
ES2194867T3 ES94911944T ES94911944T ES2194867T3 ES 2194867 T3 ES2194867 T3 ES 2194867T3 ES 94911944 T ES94911944 T ES 94911944T ES 94911944 T ES94911944 T ES 94911944T ES 2194867 T3 ES2194867 T3 ES 2194867T3
Authority
ES
Spain
Prior art keywords
apomorphine
pharmaceutical compositions
intranasal administration
dihydroergotaminesalt
dihydroergotamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94911944T
Other languages
English (en)
Inventor
Franciscus Wilhelmus He Merkus
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE9300297A external-priority patent/BE1006870A6/nl
Priority claimed from BE9300298A external-priority patent/BE1006871A6/nl
Priority claimed from BE9300299A external-priority patent/BE1006872A6/nl
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2194867T3 publication Critical patent/ES2194867T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

LA INVENCION SE REFIERE A COMPOSICIONES FARMACEUTICAS PARA LA ADMINISTRACION INTRANASAL DE DIHIDROERGOTAMINA, APOMORFINA Y MORFINA QUE COMPRENDEN UNO DE ESTOS INGREDIENTES FARMACOLOGICAMENTE ACTIVOS EN COMBINACION CON CITODEXTRINA Y/O UN DISACARIDO, Y/O UN POLISACARIDO Y/O UN ALCOHOL DE AZUCAR.
ES94911944T 1993-03-26 1994-03-18 Composiciones farmaceuticas para la administracion intranasal de apomorfina. Expired - Lifetime ES2194867T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BE9300297A BE1006870A6 (nl) 1993-03-26 1993-03-26 Nasale farmaceutische preparaten met morfine.
BE9300298A BE1006871A6 (nl) 1993-03-26 1993-03-26 Nasale farmaceutische preparaten met apomorfine.
BE9300299A BE1006872A6 (nl) 1993-03-26 1993-03-26 Nasale farmaceutische preparaten met dihydroergotamine (dhe).

Publications (1)

Publication Number Publication Date
ES2194867T3 true ES2194867T3 (es) 2003-12-01

Family

ID=27159799

Family Applications (2)

Application Number Title Priority Date Filing Date
ES94911944T Expired - Lifetime ES2194867T3 (es) 1993-03-26 1994-03-18 Composiciones farmaceuticas para la administracion intranasal de apomorfina.
ES98109002T Expired - Lifetime ES2239369T3 (es) 1993-03-26 1994-03-18 Composiciones farmaceuticas para administracion intranasal de dihidroergotamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES98109002T Expired - Lifetime ES2239369T3 (es) 1993-03-26 1994-03-18 Composiciones farmaceuticas para administracion intranasal de dihidroergotamina.

Country Status (10)

Country Link
US (2) US5756483A (es)
EP (2) EP0865789B1 (es)
JP (2) JPH08508472A (es)
AT (2) ATE241984T1 (es)
AU (1) AU6428894A (es)
DE (2) DE69434304T2 (es)
DK (2) DK0865789T3 (es)
ES (2) ES2194867T3 (es)
PT (2) PT865789E (es)
WO (1) WO1994022445A2 (es)

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US6436950B1 (en) * 1998-08-14 2002-08-20 Nastech Pharmaceutical Company, Inc. Nasal delivery of apomorphine
US20020002175A1 (en) * 2000-09-19 2002-01-03 Charanjit Behl Nasal delivery of apomorphine in combination with glycol derivatives
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Also Published As

Publication number Publication date
DE69432789T2 (de) 2003-12-04
PT689438E (pt) 2003-10-31
EP0865789A3 (en) 1999-01-07
US5756483A (en) 1998-05-26
EP0689438B1 (en) 2003-06-04
ATE241984T1 (de) 2003-06-15
JPH08508472A (ja) 1996-09-10
DK0689438T3 (da) 2003-09-29
US5942251A (en) 1999-08-24
PT865789E (pt) 2005-05-31
EP0865789B1 (en) 2005-03-16
AU6428894A (en) 1994-10-24
DE69434304D1 (de) 2005-04-21
DK0865789T3 (da) 2005-07-18
EP0865789A2 (en) 1998-09-23
DE69432789D1 (de) 2003-07-10
JP2005041884A (ja) 2005-02-17
WO1994022445A3 (en) 1995-01-05
WO1994022445A2 (en) 1994-10-13
EP0689438A1 (en) 1996-01-03
ATE290864T1 (de) 2005-04-15
DE69434304T2 (de) 2005-12-29
ES2239369T3 (es) 2005-09-16

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