ES2190581T3 - 2-aminotetralina opticamente activa, procedimiento para su preparacion y composiciones farmaceuticas que la contienen, activa en la prevencion y tratamiento de shock septico. - Google Patents

2-aminotetralina opticamente activa, procedimiento para su preparacion y composiciones farmaceuticas que la contienen, activa en la prevencion y tratamiento de shock septico.

Info

Publication number
ES2190581T3
ES2190581T3 ES98902173T ES98902173T ES2190581T3 ES 2190581 T3 ES2190581 T3 ES 2190581T3 ES 98902173 T ES98902173 T ES 98902173T ES 98902173 T ES98902173 T ES 98902173T ES 2190581 T3 ES2190581 T3 ES 2190581T3
Authority
ES
Spain
Prior art keywords
active
preparation
pharmaceutical compositions
compositions containing
septic shock
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98902173T
Other languages
English (en)
Inventor
Gian Piero Moretti
Piero Foresta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Sigma Tau Industrie Farmaceutiche Riunite SpA
Application granted granted Critical
Publication of ES2190581T3 publication Critical patent/ES2190581T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Se describe la S(-)-amino-6-fluoro-7-metoxitetralina, un procedimiento para su preparación y composiciones farmacéuticas que la contienen, la cual es activa en la prevención y tratamiento el shock séptico.
ES98902173T 1997-02-03 1998-01-28 2-aminotetralina opticamente activa, procedimiento para su preparacion y composiciones farmaceuticas que la contienen, activa en la prevencion y tratamiento de shock septico. Expired - Lifetime ES2190581T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97RM000050A IT1290910B1 (it) 1997-02-03 1997-02-03 2-amminotetralina otticamente attiva, procedimento per la sua preparazione e composizioni farmaceutiche che la contengono, attive

Publications (1)

Publication Number Publication Date
ES2190581T3 true ES2190581T3 (es) 2003-08-01

Family

ID=11404706

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98902173T Expired - Lifetime ES2190581T3 (es) 1997-02-03 1998-01-28 2-aminotetralina opticamente activa, procedimiento para su preparacion y composiciones farmaceuticas que la contienen, activa en la prevencion y tratamiento de shock septico.

Country Status (11)

Country Link
US (1) US6225501B1 (es)
EP (1) EP0968174B1 (es)
JP (1) JP2001509802A (es)
AT (1) ATE231486T1 (es)
DE (1) DE69810906T2 (es)
DK (1) DK0968174T3 (es)
ES (1) ES2190581T3 (es)
HK (1) HK1025558A1 (es)
IT (1) IT1290910B1 (es)
PT (1) PT968174E (es)
WO (1) WO1998033762A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294931B1 (it) * 1997-09-22 1999-04-23 Sigma Tau Ind Farmaceuti Derivati della 2-amminotetralina procedimento per la loro preparazione e composizioni farmaceutiche che li contengono, attive nella
IT1317050B1 (it) * 2000-06-23 2003-05-26 Sigma Tau Ind Farmaceuti Tetraline 2,6,7-sostituite utili per la preparazione di un medicamentoad attivita' inibitrice della fosfodiesterasi iv.
CN103360360A (zh) * 2012-04-10 2013-10-23 肖竹平 一种基于二氢杨梅素制备(+)-没食子儿茶素的方法
JP2020536870A (ja) 2017-10-05 2020-12-17 バイオジェン インコーポレイテッド アルファカルボキサミドピロリジン誘導体の調製方法
AU2020272878A1 (en) * 2019-04-10 2021-12-02 Biogen Inc. Processes for preparing alpha-carboxamide pyrrolidine derivatives
CN115724758A (zh) * 2021-08-24 2023-03-03 杭州中美华东制药有限公司 喜树碱衍生物中间体及其合成方法和利用中间体合成喜树碱衍生物的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241988B (it) * 1990-06-15 1994-02-02 Sigma Tau Ind Farmaceuti 2- amminotetraline-6, 7-sostituite attive come immunomodulanti e composizioni farmaceutiche che le contengono
IT1278045B1 (it) * 1995-03-09 1997-11-17 Sigma Tau Ind Farmaceuti Uso di 2-amminotetraline-6,7-sostituite per la preparazione di composizioni farmaceutiche atte al trattamento dello shock, e di

Also Published As

Publication number Publication date
WO1998033762A1 (en) 1998-08-06
DE69810906D1 (de) 2003-02-27
ATE231486T1 (de) 2003-02-15
HK1025558A1 (en) 2000-11-17
IT1290910B1 (it) 1998-12-14
EP0968174A1 (en) 2000-01-05
PT968174E (pt) 2003-06-30
DK0968174T3 (da) 2003-05-12
DE69810906T2 (de) 2003-11-13
EP0968174B1 (en) 2003-01-22
JP2001509802A (ja) 2001-07-24
ITRM970050A1 (it) 1998-08-03
US6225501B1 (en) 2001-05-01

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