ES2188139T3 - Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico. - Google Patents
Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico.Info
- Publication number
- ES2188139T3 ES2188139T3 ES99909015T ES99909015T ES2188139T3 ES 2188139 T3 ES2188139 T3 ES 2188139T3 ES 99909015 T ES99909015 T ES 99909015T ES 99909015 T ES99909015 T ES 99909015T ES 2188139 T3 ES2188139 T3 ES 2188139T3
- Authority
- ES
- Spain
- Prior art keywords
- phosphocalcico
- hydroxiapatite
- biomaterial
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
- C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
- C04B28/346—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders the phosphate binder being present in the starting composition as a mixture of free acid and one or more phosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
- A61K6/838—Phosphorus compounds, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
- A61K6/864—Phosphate cements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B25/00—Phosphorus; Compounds thereof
- C01B25/16—Oxyacids of phosphorus; Salts thereof
- C01B25/26—Phosphates
- C01B25/32—Phosphates of magnesium, calcium, strontium, or barium
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
- C04B28/34—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing cold phosphate binders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
- C04B2111/00474—Uses not provided for elsewhere in C04B2111/00
- C04B2111/00836—Uses not provided for elsewhere in C04B2111/00 for medical or dental applications
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Inorganic Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Veterinary Medicine (AREA)
- Ceramic Engineering (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Structural Engineering (AREA)
- Plastic & Reconstructive Surgery (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Transplantation (AREA)
- Surgery (AREA)
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Abstract
La invención ser refiere a un procedimiento para preparar un biomaterial en el que la fase de endurecimiento se lleva a cabo en la zona de utilización, el procedimiento comprende los siguientes pasos: a) preparar previamente un producto sólido en polvo a partir de fosfato tricálcico y de fosfato tetracálcico con una proporción Ca/P que oscila básicamente entre 1.40 y 1.90; b) preparar una solución acuosa que contenga iones de calcio e iones de fosfato con una proporción Ca/P superior a 0,20 e inferior a 0,50; y c) mezclar la solución acuosa y el producto en polvo añadiendo, sí se necesitase, agua, de manera que la proporción de líquido/sólido de la mezcla oscile entre 0,30 y 0,65 y la proporción de Ca/P de la pasta resultante oscile entre 1,50 y 1,67, la pasta se dispone en la zona de utilización y se endurece in situ.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9803459A FR2776282B1 (fr) | 1998-03-20 | 1998-03-20 | Procede de preparation d'un biomateriau a base d'hydroxyapatite, biomateriau obtenu et application chirurgicale ou dentaire |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2188139T3 true ES2188139T3 (es) | 2003-06-16 |
Family
ID=9524294
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES99909015T Expired - Lifetime ES2188139T3 (es) | 1998-03-20 | 1999-03-17 | Procedimiento para la preparacion de un biomaterial esencialmente constituido por un hidroxiapatito fosfocalcico. |
Country Status (8)
Country | Link |
---|---|
US (2) | US6521264B1 (es) |
EP (1) | EP0984902B1 (es) |
AT (1) | ATE228481T1 (es) |
AU (1) | AU2841099A (es) |
DE (1) | DE69904127D1 (es) |
ES (1) | ES2188139T3 (es) |
FR (1) | FR2776282B1 (es) |
WO (1) | WO1999048809A1 (es) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2805748B1 (fr) | 2000-03-01 | 2002-09-13 | Ceravic | Procede de preparation d'un materiau pateux phosphocalcique injectable en vue de former un biomateriau apatitique et application chirurgicale ou dentaire |
DE10032220A1 (de) | 2000-07-03 | 2002-01-24 | Sanatis Gmbh | Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung |
US6649669B2 (en) * | 2001-12-28 | 2003-11-18 | American Dental Association Health Foundation | Single solution bonding formulation |
US20040127563A1 (en) * | 2002-03-22 | 2004-07-01 | Deslauriers Richard J. | Methods of performing medical procedures which promote bone growth, compositions which promote bone growth, and methods of making such compositions |
AUPS244002A0 (en) * | 2002-05-20 | 2002-06-13 | John Kohnke Products Pty Ltd | Agent delivery system |
AU2003229357B2 (en) * | 2002-05-20 | 2008-05-15 | John Kohnke | Agent delivery system |
US7273523B2 (en) | 2002-06-07 | 2007-09-25 | Kyphon Inc. | Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof |
US7699925B2 (en) | 2002-06-20 | 2010-04-20 | Doxa Ab | System for a dental filling material or implant material, and powdered material, hydration liquid, implant material and method of achieving bonding |
ES2222778B2 (es) * | 2002-07-04 | 2005-10-01 | Universidade De Santiago De Compostela | PROCEDIMIENTO PARA INCREMENTAR LAS PROPIEDADES MECANICAS DE BIOCERAMICAS DE FOSFATOS CALCICOS MEDIANTE LA ADICION DE GELES CON RELACION Ca/P CONTROLADA A LOS POLVOS DE MATERIAS PRIMAS. |
US8876532B2 (en) | 2002-07-31 | 2014-11-04 | Dentsply International Inc. | Bone repair putty |
US7842300B2 (en) * | 2002-07-31 | 2010-11-30 | Dentsply International, Inc. | Bone repair putty |
JP4647603B2 (ja) * | 2003-08-08 | 2011-03-09 | デンツプリー・インターナショナル・インコーポレーテッド | 歯科用セメントや関連した骨セメントに使用するホスホシリケートスラリーを得るための方法と製造物 |
US7981461B2 (en) * | 2004-01-30 | 2011-07-19 | Georgette Frederick S | Metallic bone implant having improved implantability and method of making the same |
CA2575740A1 (en) * | 2004-03-24 | 2005-10-13 | Doctor's Research Group, Inc. | Methods of performing medical procedures that promote bone growth, methods of making compositions that promote bone growth, and apparatus for use in such methods |
DE102004063912B4 (de) * | 2004-04-22 | 2007-09-20 | Siltronic Ag | Verfahren zum versandfertigen Verpacken von Halbleiterscheiben |
CA2564687A1 (en) | 2004-04-27 | 2005-11-10 | Kyphon Inc. | Bone substitute compositions and method of use |
ATE480214T1 (de) | 2004-11-16 | 2010-09-15 | 3M Innovative Properties Co | Dentalfüllstoffe, verfahren, zusammensetzungen mit einem caseinat |
AU2005306857A1 (en) | 2004-11-16 | 2006-05-26 | 3M Innovative Properties Company | Dental compositions with calcium phosphorus releasing glass |
CA2587275A1 (en) | 2004-11-16 | 2006-05-26 | 3M Innovative Properties Company | Dental fillers and compositions including phosphate salts |
EP1819312B1 (en) | 2004-11-16 | 2014-12-17 | 3M Innovative Properties Company | Dental fillers including a phosphorus-containing surface treatment |
US7651701B2 (en) * | 2005-08-29 | 2010-01-26 | Sanatis Gmbh | Bone cement composition and method of making the same |
US8287914B2 (en) * | 2006-01-12 | 2012-10-16 | Rutgers, The State University Of New Jersey | Biomimetic hydroxyapatite synthesis |
US20100040668A1 (en) * | 2006-01-12 | 2010-02-18 | Rutgers, The State University Of New Jersey | Biomimetic Hydroxyapatite Composite Materials and Methods for the Preparation Thereof |
US8361129B2 (en) * | 2006-04-28 | 2013-01-29 | Depuy Spine, Inc. | Large diameter bone anchor assembly |
US7754005B2 (en) * | 2006-05-02 | 2010-07-13 | Kyphon Sarl | Bone cement compositions comprising an indicator agent and related methods thereof |
US7507286B2 (en) * | 2006-06-08 | 2009-03-24 | Sanatis Gmbh | Self-foaming cement for void filling and/or delivery systems |
AU2007300585A1 (en) * | 2006-09-21 | 2008-04-03 | Kyphon Sarl | Diammonium phosphate and other ammonium salts and their use in preventing clotting |
WO2008073190A2 (en) * | 2006-11-03 | 2008-06-19 | Kyphon Sarl | Materials and methods and systems for delivering localized medical treatments |
EP2120734B1 (en) | 2006-12-15 | 2015-12-02 | Gmedelaware 2 LLC | Drills for vertebrostenting |
EP2229130A2 (en) * | 2007-12-13 | 2010-09-22 | 3M Innovative Properties Company | Remineralizing compositions and methods |
US7968616B2 (en) * | 2008-04-22 | 2011-06-28 | Kyphon Sarl | Bone cement composition and method |
WO2009155319A1 (en) | 2008-06-17 | 2009-12-23 | Soteira, Inc. | Devices and methods for fracture reduction |
US8790707B2 (en) * | 2008-12-11 | 2014-07-29 | 3M Innovative Properties Company | Surface-treated calcium phosphate particles suitable for oral care and dental compositions |
WO2010111246A1 (en) | 2009-03-23 | 2010-09-30 | Soteira, Inc. | Devices and methods for vertebrostenting |
US8361123B2 (en) | 2009-10-16 | 2013-01-29 | Depuy Spine, Inc. | Bone anchor assemblies and methods of manufacturing and use thereof |
BR112018010091A2 (pt) | 2015-11-19 | 2019-02-05 | Fantarella & Harewood LLC | colutório não alcoólico e método para inibir o crescimento de células de bactérias na boca |
PL442461A1 (pl) * | 2022-10-06 | 2024-04-08 | Sieć Badawcza Łukasiewicz - Instytut Ceramiki I Materiałów Budowlanych | Syntetyczny bioaktywny materiał hydroksyapatytowy oraz sposób jego otrzymywania |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US33161A (en) * | 1861-08-27 | Improvement in molds for earthen or cement pipes | ||
US33221A (en) * | 1861-09-03 | Improvement in soap | ||
USRE33221E (en) * | 1982-04-29 | 1990-05-22 | American Dental Association Health Foundation | Dental restorative cement pastes |
USRE33161E (en) * | 1982-04-29 | 1990-02-06 | American Dental Association Health Foundation | Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements |
US4843112A (en) * | 1987-03-12 | 1989-06-27 | The Beth Israel Hospital Association | Bioerodable implant composition |
JPS6456056A (en) * | 1987-08-26 | 1989-03-02 | Dental Chem Co Ltd | Hydroxyapatite bone filling material |
EP0323632B1 (en) * | 1987-12-28 | 1992-07-15 | Asahi Kogaku Kogyo Kabushiki Kaisha | Composition for forming calcium phosphate type setting material and process for producing setting material |
US5129905A (en) * | 1988-04-20 | 1992-07-14 | Norian Corporation | Methods for in situ prepared calcium phosphate minerals |
US5605713A (en) * | 1991-11-22 | 1997-02-25 | Boltong; Maria G. | Process for the preparation of calcium phosphate cements and its application as bio-materials |
FR2693716B1 (fr) * | 1992-07-20 | 1994-10-21 | Toulouse Inst Nat Polytech | Procédé d'obtention d'hydroxyapatite phosphocalcique, applications au comblement osseux ou dentaire, ou au moulage de pièces, et produits utilisés. |
US5522893A (en) * | 1993-03-12 | 1996-06-04 | American Dental Association Health Foundation | Calcium phosphate hydroxyapatite precursor and methods for making and using the same |
US5525148A (en) * | 1993-09-24 | 1996-06-11 | American Dental Association Health Foundation | Self-setting calcium phosphate cements and methods for preparing and using them |
FR2749756B1 (fr) * | 1996-06-14 | 1998-09-11 | Bioland | Procede de preparation d'un materiau composite implantable, materiau obtenu, implant comprenant ce materiau et kit de mise en oeuvre |
FR2805747B1 (fr) * | 2000-03-01 | 2003-03-14 | Teknimed | Procede de preparation d'un materiau pateux phosphocalcique injectable en vue de former un biomateriau apatitique et application chirurgicale ou dentaire |
-
1998
- 1998-03-20 FR FR9803459A patent/FR2776282B1/fr not_active Expired - Fee Related
-
1999
- 1999-03-17 EP EP99909015A patent/EP0984902B1/fr not_active Expired - Lifetime
- 1999-03-17 AT AT99909015T patent/ATE228481T1/de not_active IP Right Cessation
- 1999-03-17 AU AU28410/99A patent/AU2841099A/en not_active Abandoned
- 1999-03-17 US US09/424,313 patent/US6521264B1/en not_active Expired - Fee Related
- 1999-03-17 DE DE69904127T patent/DE69904127D1/de not_active Expired - Lifetime
- 1999-03-17 ES ES99909015T patent/ES2188139T3/es not_active Expired - Lifetime
- 1999-03-17 WO PCT/FR1999/000595 patent/WO1999048809A1/fr active IP Right Grant
-
2003
- 2003-01-13 US US10/340,703 patent/US20030108589A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69904127D1 (de) | 2003-01-09 |
US6521264B1 (en) | 2003-02-18 |
US20030108589A1 (en) | 2003-06-12 |
EP0984902A1 (fr) | 2000-03-15 |
AU2841099A (en) | 1999-10-18 |
WO1999048809A1 (fr) | 1999-09-30 |
FR2776282A1 (fr) | 1999-09-24 |
ATE228481T1 (de) | 2002-12-15 |
FR2776282B1 (fr) | 2000-05-19 |
EP0984902B1 (fr) | 2002-11-27 |
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