ES2183714A1 - Fabrication of oxalate based oncology treatment agent useful in chemical industry, comprising mixing cyclohexanodiamine and tetraiodoplatinite solutions with silver nitrate and potassium oxalate - Google Patents

Fabrication of oxalate based oncology treatment agent useful in chemical industry, comprising mixing cyclohexanodiamine and tetraiodoplatinite solutions with silver nitrate and potassium oxalate

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Publication number
ES2183714A1
ES2183714A1 ES200101213A ES200101213A ES2183714A1 ES 2183714 A1 ES2183714 A1 ES 2183714A1 ES 200101213 A ES200101213 A ES 200101213A ES 200101213 A ES200101213 A ES 200101213A ES 2183714 A1 ES2183714 A1 ES 2183714A1
Authority
ES
Spain
Prior art keywords
oxalate
cyclohexanodiamine
tetraiodoplatinite
mixing
chemical industry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200101213A
Other languages
Spanish (es)
Other versions
ES2183714B1 (en
Inventor
Carlos Gaozza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DESYNTH S A
Original Assignee
DESYNTH S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DESYNTH S A filed Critical DESYNTH S A
Priority to ES200101213A priority Critical patent/ES2183714B1/en
Publication of ES2183714A1 publication Critical patent/ES2183714A1/en
Application granted granted Critical
Publication of ES2183714B1 publication Critical patent/ES2183714B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

An oxalate-based oncology treatment agent, useful in the chemical industry, is fabricated by mixing (1R,2R)-cyclohexanodiamine based aqueous solution with potassium tetraiodoplatinite (I4PtK2) aqueous solution. The resulting (1R,2R-cyclohexanodiamine)-platinum (II), after silver nitrate solution treatment, receives excess of potassium oxalate aqueous solution. The crystalline product is (1R,2R)-cyclohexanodiamine)-platinum (II) oxalate.
ES200101213A 2001-05-25 2001-05-25 A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II). Expired - Fee Related ES2183714B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES200101213A ES2183714B1 (en) 2001-05-25 2001-05-25 A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II).

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200101213A ES2183714B1 (en) 2001-05-25 2001-05-25 A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II).

Publications (2)

Publication Number Publication Date
ES2183714A1 true ES2183714A1 (en) 2003-03-16
ES2183714B1 ES2183714B1 (en) 2004-01-16

Family

ID=8497855

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200101213A Expired - Fee Related ES2183714B1 (en) 2001-05-25 2001-05-25 A PROCEDURE FOR THE MANUFACTURE OF OXALATE (1R, 2R-CYCLHEXANODIAMINE) -PLATINO (II).

Country Status (1)

Country Link
ES (1) ES2183714B1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010081924A1 (en) * 2009-01-13 2010-07-22 Capital, Business Y Gestión De Finanzas, S.L. Process for preparing pharmaceutical-grade neutral platinum (ii) antineoplastic derivatives having low silver content
WO2010149337A1 (en) 2009-06-26 2010-12-29 Umicore Ag & Co. Kg Process for preparation of 1,2-diamino-cyclohexane-platinum (ii) complexes

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617043A1 (en) * 1992-01-13 1994-09-28 Tanaka Kikinzoku Kogyo K.K. Platinum compound and process of preparing same
EP0625523A1 (en) * 1993-05-21 1994-11-23 Tanaka Kikinzoku Kogyo K.K. Cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same
ES2125320T3 (en) * 1992-04-22 1999-03-01 Tanaka Precious Metal Ind CIS-OXALATE (TRANS-L-1,2-CYCLOHEXANDIAMINE) PT (II) OPTICALLY PURE AND PROCEDURE FOR SOLVING OPTICAL ISOMERS OF A PLATINUM COMPLEX COMPOSITE.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617043A1 (en) * 1992-01-13 1994-09-28 Tanaka Kikinzoku Kogyo K.K. Platinum compound and process of preparing same
ES2125320T3 (en) * 1992-04-22 1999-03-01 Tanaka Precious Metal Ind CIS-OXALATE (TRANS-L-1,2-CYCLOHEXANDIAMINE) PT (II) OPTICALLY PURE AND PROCEDURE FOR SOLVING OPTICAL ISOMERS OF A PLATINUM COMPLEX COMPOSITE.
EP0625523A1 (en) * 1993-05-21 1994-11-23 Tanaka Kikinzoku Kogyo K.K. Cis-oxalato(trans-L-1,2-cyclohexanediamine) Pt(II) complex having high optical purity and process of preparing same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010081924A1 (en) * 2009-01-13 2010-07-22 Capital, Business Y Gestión De Finanzas, S.L. Process for preparing pharmaceutical-grade neutral platinum (ii) antineoplastic derivatives having low silver content
WO2010149337A1 (en) 2009-06-26 2010-12-29 Umicore Ag & Co. Kg Process for preparation of 1,2-diamino-cyclohexane-platinum (ii) complexes
US8637692B2 (en) 2009-06-26 2014-01-28 Umicore Ag & Co. Kg Process for preparation of 1,2-diamino-cyclohexane-platinum (II) complexes

Also Published As

Publication number Publication date
ES2183714B1 (en) 2004-01-16

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