ES2183251T3 - Determinacion inmunoquimica de analitos multivalentes. - Google Patents

Determinacion inmunoquimica de analitos multivalentes.

Info

Publication number
ES2183251T3
ES2183251T3 ES98108224T ES98108224T ES2183251T3 ES 2183251 T3 ES2183251 T3 ES 2183251T3 ES 98108224 T ES98108224 T ES 98108224T ES 98108224 T ES98108224 T ES 98108224T ES 2183251 T3 ES2183251 T3 ES 2183251T3
Authority
ES
Spain
Prior art keywords
analytics
multivalent
immunochemical determination
immunochemical
binding partners
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98108224T
Other languages
English (en)
Inventor
Stefan Dr Brust
Hans-Peter Dr Hauser
Stefan Dr Knapp
Helmut Dr Peters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics GmbH Germany
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of ES2183251T3 publication Critical patent/ES2183251T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO INMUNOQUIMICO PARA LA DETERMINACION CUALITATIVA O CUANTITATIVA DE UN ANALIZANDO. PARA ELLO, UN PRIMER Y UN SEGUNDO LIGANDO SE PONEN EN CONTACTO CON EL ANALIZANDO, Y A CONTINUACION, MEDIANTE PROCEDIMIENTOS CONOCIDOS, SE DETECTA EL ENLACE DE DICHOS LIGANDOS CON LOS ANALIZANDOS. DE ACUERDO CON LA INVENCION, AMBOS LIGANDOS SE CREAN EN UN MISMO HUESPED MEDIANTE TECNICAS DE INGENIERIA GENETICA Y UTILIZANDO DIFERENTES VECTORES (V1 Y V2) PARA LA EXPRESION DE LAS PROTEINAS DE FUSION, DE MANERA QUE EL PRIMER LIGANDO SE EXPRESA COMO LA PROTEINA DE FUSION F1 EN EL VECTOR V1 Y EL SEGUNDO LIGANDO SE EXPRESA COMO LA PROTEINA DE FUSION F2 EN EL VECTOR V2. LA VENTAJA DE ESTE PROCEDIMIENTO, QUE TAMBIEN SIRVE PARA EL ANALISIS SIMULTANEO DE VARIOS ANALIZANDOS, RADICA EN SU MAYOR SENSIBILIDAD Y ESPECIFICIDAD EN RELACION CON OTROS METODOS CONOCIDOS.
ES98108224T 1997-06-04 1998-05-06 Determinacion inmunoquimica de analitos multivalentes. Expired - Lifetime ES2183251T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19723463A DE19723463A1 (de) 1997-06-04 1997-06-04 Immunchemische Bestimmung von multivalenten Analyten

Publications (1)

Publication Number Publication Date
ES2183251T3 true ES2183251T3 (es) 2003-03-16

Family

ID=7831400

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98108224T Expired - Lifetime ES2183251T3 (es) 1997-06-04 1998-05-06 Determinacion inmunoquimica de analitos multivalentes.

Country Status (7)

Country Link
US (1) US6120990A (es)
EP (1) EP0882985B1 (es)
JP (1) JP4063405B2 (es)
AT (1) ATE223047T1 (es)
CA (1) CA2234416C (es)
DE (2) DE19723463A1 (es)
ES (1) ES2183251T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ291153A (en) * 1994-07-25 1999-01-28 Boehringer Mannheim Gmbh Determination of a specific antibody using multiple antigens containing several epitope regions which react with the antibody
AR027370A1 (es) * 2000-02-17 2003-03-26 Lg Chemical Ltd Inmunoensayo y reactivo de diagnostico para malaria, y correspondientes metodos de preparacion, vectores de expresion y transformantes
EP1288308A1 (en) * 2001-08-28 2003-03-05 Roche Diagnostics GmbH A method for the determination of multiple analytes
GB0128583D0 (en) 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes
EP1724281B1 (en) * 2003-12-23 2013-02-13 Biokit S.A. Pathogenic infection detection compositions and methods
US8586347B2 (en) 2010-09-15 2013-11-19 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
AU2011230619C1 (en) 2010-03-25 2016-06-23 Oregon Health & Science University CMV glycoproteins and recombinant vectors
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
EP2586461A1 (en) 2011-10-27 2013-05-01 Christopher L. Parks Viral particles derived from an enveloped virus
FR2987836A1 (fr) * 2012-03-09 2013-09-13 Biomerieux Sa Peptides d'interference et procede de detection de microorganismes
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3588134T2 (de) * 1984-12-24 1997-03-20 Genentech Inc Fusionen von AIDS-verwandten Polypeptiden
AU615670B2 (en) * 1987-09-04 1991-10-10 Murex Diagnostics Corporation Immunoassay and biological constructs for use therein
US5322769A (en) * 1988-03-11 1994-06-21 Abbott Laboratories Methods for using CKS fusion proteins
US5480972A (en) * 1992-10-30 1996-01-02 The University Of Melbourne Allergenic proteins from Johnson grass pollen
US5496934A (en) * 1993-04-14 1996-03-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acids encoding a cellulose binding domain

Also Published As

Publication number Publication date
EP0882985A3 (de) 1999-12-15
CA2234416C (en) 2007-10-23
CA2234416A1 (en) 1998-12-04
DE19723463A1 (de) 1998-12-10
JP4063405B2 (ja) 2008-03-19
US6120990A (en) 2000-09-19
EP0882985A2 (de) 1998-12-09
JPH10332696A (ja) 1998-12-18
ATE223047T1 (de) 2002-09-15
EP0882985B1 (de) 2002-08-28
DE59805288D1 (de) 2002-10-02

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