ES2180433A1 - Use of haematopoietic stem cells in the generation of neural stem cells - Google Patents
Use of haematopoietic stem cells in the generation of neural stem cellsInfo
- Publication number
- ES2180433A1 ES2180433A1 ES200101223A ES200101223A ES2180433A1 ES 2180433 A1 ES2180433 A1 ES 2180433A1 ES 200101223 A ES200101223 A ES 200101223A ES 200101223 A ES200101223 A ES 200101223A ES 2180433 A1 ES2180433 A1 ES 2180433A1
- Authority
- ES
- Spain
- Prior art keywords
- stem cells
- haematopoietic
- generation
- cells
- haematopoietic stem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The invention relates to the production of neural stem cells consisting in cultivating haematopoietic stem cells in conditions that promote the growth and differentiation of said haematopoietic stem cells into neural stem cells which can be used to regenerate populations of cells lost in the nervous system. The invention also relates to the use of haematopoietic stem cells in the production of a pharmaceutical composition that is used to treat neurodegenerative diseases and/or pathological conditions involving degenerated neuronal cells, both in localised and multifocal processes.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200101223A ES2180433B1 (en) | 2001-05-28 | 2001-05-28 | EMPLOYMENT OF HEMATOPOYETIC MOTHER CELLS IN THE GENERATION OF NEURAL MOTHER CELLS. |
PCT/ES2002/000253 WO2002096439A1 (en) | 2001-05-28 | 2002-05-27 | Use of haematopoietic stem cells in the generation of neural stem cells |
IL15435602A IL154356A0 (en) | 2001-05-28 | 2002-05-27 | The use of haematopoietic stem cells in the generation of neural stem cells |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200101223A ES2180433B1 (en) | 2001-05-28 | 2001-05-28 | EMPLOYMENT OF HEMATOPOYETIC MOTHER CELLS IN THE GENERATION OF NEURAL MOTHER CELLS. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2180433A1 true ES2180433A1 (en) | 2003-02-01 |
ES2180433B1 ES2180433B1 (en) | 2004-05-16 |
Family
ID=8497869
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200101223A Expired - Fee Related ES2180433B1 (en) | 2001-05-28 | 2001-05-28 | EMPLOYMENT OF HEMATOPOYETIC MOTHER CELLS IN THE GENERATION OF NEURAL MOTHER CELLS. |
Country Status (3)
Country | Link |
---|---|
ES (1) | ES2180433B1 (en) |
IL (1) | IL154356A0 (en) |
WO (1) | WO2002096439A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030194454A1 (en) | 1998-07-28 | 2003-10-16 | Bessette Steven M. | Pesticidal compositions containing rosemary oil and wintergreen oil |
WO2018071898A1 (en) * | 2016-10-14 | 2018-04-19 | Children's Medical Center Corporation | Compositions and methods for treating diseases and disorders of the central nervous system |
WO2018136434A1 (en) | 2017-01-17 | 2018-07-26 | Children's Medical Center Corporation | Compositions and methods for diagnosing and treating peroxisomal diseases |
CA3050691A1 (en) | 2017-01-17 | 2018-07-26 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating lysosomal storage diseases and disorders |
CN107320495A (en) * | 2017-06-19 | 2017-11-07 | 北正赛欧(北京)生物科技有限公司 | Composition and its application for promoting cellular damage reparation |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999056759A1 (en) * | 1998-05-07 | 1999-11-11 | University Of South Florida | Bone marrow cells as a source of neurons for brain and spinal cord repair |
WO2000069448A1 (en) * | 1999-05-14 | 2000-11-23 | Henry Ford Health System | Bone marrow transplantation for treatment of stroke |
WO2001021766A2 (en) * | 1999-09-23 | 2001-03-29 | Cell Science Therapeutics | Methods and devices for obtaining non-hematopoietic lineage cells from hematopoietic progenitor cells |
-
2001
- 2001-05-28 ES ES200101223A patent/ES2180433B1/en not_active Expired - Fee Related
-
2002
- 2002-05-27 IL IL15435602A patent/IL154356A0/en unknown
- 2002-05-27 WO PCT/ES2002/000253 patent/WO2002096439A1/en not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999056759A1 (en) * | 1998-05-07 | 1999-11-11 | University Of South Florida | Bone marrow cells as a source of neurons for brain and spinal cord repair |
WO2000069448A1 (en) * | 1999-05-14 | 2000-11-23 | Henry Ford Health System | Bone marrow transplantation for treatment of stroke |
WO2001021766A2 (en) * | 1999-09-23 | 2001-03-29 | Cell Science Therapeutics | Methods and devices for obtaining non-hematopoietic lineage cells from hematopoietic progenitor cells |
Non-Patent Citations (3)
Title |
---|
MEZEY EVA et al. Bone marrow: A possible alternative source of cells in the adult nervous system. (2000) European Journal of Pharmacology, Vol. 405, pßginas 297-302. * |
REYES MORAYMA et al. Turning marrow into brain: Generation of glial and neuronal cells from adult bone marrow. (1999) Blood, Vol. 94, 10, Suppl. 1 Part 1, pßgina 377a. * |
WOODBURY, DALE et al. Adult rat and human bone marrow stromal cells differentiate into neurons. (2000) Journal of Neuroscience Research, 61 (4), pßginas 364-370. * |
Also Published As
Publication number | Publication date |
---|---|
WO2002096439A1 (en) | 2002-12-05 |
IL154356A0 (en) | 2003-09-17 |
ES2180433B1 (en) | 2004-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA2A | Application withdrawn |
Effective date: 20010704 |
|
EC2A | Search report published |
Date of ref document: 20030201 Kind code of ref document: A1 |
|
FG2A | Definitive protection |
Ref document number: 2180433B1 Country of ref document: ES |
|
FD2A | Announcement of lapse in spain |
Effective date: 20210903 |