ES2177659T3 - Compuestos a base de silicio biologicamente activos y aplicaciones de los mismos. - Google Patents

Compuestos a base de silicio biologicamente activos y aplicaciones de los mismos.

Info

Publication number
ES2177659T3
ES2177659T3 ES95933457T ES95933457T ES2177659T3 ES 2177659 T3 ES2177659 T3 ES 2177659T3 ES 95933457 T ES95933457 T ES 95933457T ES 95933457 T ES95933457 T ES 95933457T ES 2177659 T3 ES2177659 T3 ES 2177659T3
Authority
ES
Spain
Prior art keywords
links
biologically active
silicon based
hydrolyable
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95933457T
Other languages
English (en)
Inventor
Marie-Christine Seguin
Jean Gueyne
Jean-Francois Nicolay
Andre Franco
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exsymol SAM
Original Assignee
Exsymol SAM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9467728&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2177659(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Exsymol SAM filed Critical Exsymol SAM
Application granted granted Critical
Publication of ES2177659T3 publication Critical patent/ES2177659T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1896—Compounds having one or more Si-O-acyl linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/695—Silicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585—Organosilicon compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Silicon Polymers (AREA)

Abstract

COMPUESTO A BASE DE SILICIO DE FORMULA GENERAL: A) EN LA QUE A, B, C, D SON RADICALES DIFERENTES DE OH ENLAZADOS A SI POR ENLACES COVALENTES: DOS O TRES DE ESTOS ENLACES CON SI SON ENLACES DEL TIPO SI-O-C, SI-S-C O SI-N-C, HIDROLIZABLES IN VIVO CON FORMACION DE ENLACES SI-OH BIOLOGICAMENTE ACTIVOS, PARTICULARMENTE EN CONTACTO CON TEJIDOS VIVOS, SIENDO LOS ENLACES A Y D DE LA FORMULA B) SIEMPRE HIDROLIZABLES, AL MENOS UNO DE ESTOS ENLACES HIDROLIZABLES CORRESPONDE A UN RADICAL ACILOXI, ARILOXI O VINILOXI; AL MENOS UNO DE LOS COMPUESTOS OBTENIDOS TRAS LA HIDROLISIS DE DICHOS ENLACES HIDROLIZABLES ES UN ESTABILIZANTE; Y LOS ENLACES NO HIDROLIZABLES SON DEL TIPO SI-C Y CORRESPONDEN A RADICALES HIDROCARBONADOS O FLUOROCARBONADOS PARA LOS CUALES SI NO ESTA DIRECTAMENTE ENLAZADO A UN NUCLEO FENILO.
ES95933457T 1994-09-30 1995-09-29 Compuestos a base de silicio biologicamente activos y aplicaciones de los mismos. Expired - Lifetime ES2177659T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412088A FR2725207B1 (fr) 1994-09-30 1994-09-30 Composes a base de silicium biologiquement actifs, leurs applications therapeutiques et cosmetiques

Publications (1)

Publication Number Publication Date
ES2177659T3 true ES2177659T3 (es) 2002-12-16

Family

ID=9467728

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95933457T Expired - Lifetime ES2177659T3 (es) 1994-09-30 1995-09-29 Compuestos a base de silicio biologicamente activos y aplicaciones de los mismos.

Country Status (14)

Country Link
US (1) US6211393B1 (es)
EP (1) EP0737200B1 (es)
JP (1) JP4194115B2 (es)
CN (1) CN1136316A (es)
AU (1) AU694270B2 (es)
BR (1) BRPI9506389B8 (es)
CA (1) CA2176511C (es)
CZ (1) CZ296973B6 (es)
DE (1) DE69527037T2 (es)
ES (1) ES2177659T3 (es)
FR (1) FR2725207B1 (es)
HU (1) HU225616B1 (es)
MX (1) MX9602027A (es)
WO (1) WO1996010575A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2725208B1 (fr) * 1994-09-30 1996-11-29 Exsymol Sa Procede de preparation de composes de silicium biologiquement actifs sous forme concentree
FR2761075B1 (fr) * 1997-03-24 1999-06-11 Seguin Marie Christine Nouveaux composes a base de silicium biologiquement actifs et leurs applications therapeutiques
US7595308B2 (en) 2002-11-18 2009-09-29 Grenpharma Llc Compositions for treating and/or preventing diseases characterized by the presence of metal ions
EP1583765A4 (en) * 2002-11-18 2008-03-26 Grenpharma Llc COMPOSITIONS FOR THE TREATMENT AND / OR PREVENTION OF DISEASES CHARACTERIZED BY THE PRESENCE OF METALLIC IONS
EP1812013A1 (en) * 2004-10-22 2007-08-01 Grenpharma LLC Compositions for treating and/or preventing diseases characterized by the presence of the metal ions
US20060111955A1 (en) * 2004-11-24 2006-05-25 Agilis Systems, Inc. System and method for mobile resource management with customer confirmation
DE102007063284A1 (de) * 2007-12-27 2009-07-02 Basf Se Spiroverbindungen
DE102010008982A1 (de) * 2010-02-24 2011-08-25 Bayer Innovation GmbH, 40225 Siliciumhaltiges, biologisch degradierbares Material zur anti-inflammatorischen Therapie
RU2481350C1 (ru) * 2012-02-14 2013-05-10 Общество с ограниченной ответственностью "ТРИНИТИ ФАРМА" Ортосиликат меглюмина, повышающий устойчивость организма к физическим нагрузкам, и способ его получения
EP3227306B1 (en) * 2014-12-02 2020-07-15 Merck Sharp & Dohme Corp. Process for the preparation of tert-butyl 4-((2s,5r)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxamido)piperidine-1-carboxylate and analogs thereof
WO2017055943A1 (en) * 2015-07-15 2017-04-06 Bakel Srl Cosmetic composition
FR3053249B1 (fr) 2016-07-02 2021-07-02 Estelle Piron Formulation cosmetique comprenant au moins une huile, une vitamine c et un silicium
CN112494356A (zh) * 2021-01-06 2021-03-16 台州市创嘉新材料有限公司 一种抗衰老化妆品的制备工艺

Family Cites Families (26)

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Publication number Priority date Publication date Assignee Title
US3546267A (en) * 1965-12-07 1970-12-08 Dynamit Nobel Ag Production of halogenated phenoxysilanes
CS153256B1 (es) * 1971-06-15 1974-02-25
FR2230376A1 (en) * 1973-05-24 1974-12-20 Gueyne Jean Stable solutions of siloxanic polysilanols - prepd. by hydrolysis of a silane and having pharmaceutical activity
US4006226A (en) * 1975-06-16 1977-02-01 Dow Corning Corporation Anticonvulsant diphenylsilanes
GB1465455A (en) * 1975-07-14 1977-02-23 Ir I Orch Khim Sib Medicinal preparation ofr healing wounds and treating dermatites
US4039666A (en) * 1975-12-15 1977-08-02 Dow Corning Corporation Anticonvulsant phenylsilanes
US4238401A (en) * 1978-07-24 1980-12-09 General Electric Company Alkoxysilicon materials and method for making
GB2130229A (en) * 1982-11-04 1984-05-31 Gen Electric Dialkoxysilylenolethers and method for making them
DE3331515A1 (de) * 1983-09-01 1985-03-21 Merck Patent Gmbh, 6100 Darmstadt Trialkanoyloxysilane
US4528191A (en) * 1983-10-25 1985-07-09 Sandoz, Inc. Disilacyclohexane derivatives in anti-fertility agents
DE3346909A1 (de) * 1983-12-24 1985-07-04 Dynamit Nobel Ag, 5210 Troisdorf Neue alkenylbenzoyloxysilane und ihre verwendung in haftklebern
US4772593A (en) * 1985-07-01 1988-09-20 The Dow Chemical Company Alkoxysilane compounds in the treatment of swine dysentery
US4689181A (en) * 1985-12-27 1987-08-25 Dow Corning Corporation Fluorine-containing organosilanes useful as magnetic media lubricants
CA1306192C (en) * 1986-12-17 1992-08-11 Andrew Hamilton Ward Medicament containing a silicon derivative of menthol
FR2619113B2 (fr) * 1987-05-26 1991-06-28 Exsymol Sa Nouveaux produits de condensation de silanols, leurs preparation et application
US4870191A (en) * 1988-07-22 1989-09-26 Ethyl Corporation Silicon containing reaction product
EP0368481A3 (en) * 1988-10-14 1991-03-27 Medex, Inc. Immobilized fluorophores for oxygen sensors
US4908355A (en) * 1989-01-09 1990-03-13 Dow Corning Corporation Skin treatment method
JPH07113034B2 (ja) * 1989-04-28 1995-12-06 信越化学工業株式会社 有機ケイ素化合物
CA2042155A1 (en) * 1990-05-29 1991-11-30 Clint W. Carpenter Surface-modified micaceous particulates having improved dispersibility in aqueous media
US5648511A (en) * 1990-11-19 1997-07-15 G.D. Searle & Co. Method for making intermediates useful in the synthesis of retroviral protease inhibitors
FR2683455B1 (fr) * 1991-11-08 1994-02-11 Gilbert Guenoun Composition pour la stimulation de la synthese localisee des tissus conjonctifs.
US5274157A (en) * 1991-11-12 1993-12-28 Ciba-Geigy Corporation Protected formylpentanediols, hydroxymethylpentanediols, process for their preparation and intermediates
JP2507251B2 (ja) * 1991-12-04 1996-06-12 信越化学工業株式会社 ２−トリメトキシシリルプロピオン酸エステル
DE69316421T2 (de) * 1992-04-01 1998-06-04 Tonen Corp Silanverbindung und Verfahren zur deren Herstellung
JPH0667485A (ja) * 1992-08-25 1994-03-11 Canon Inc 画像記録装置

Also Published As

Publication number Publication date
HUT74608A (en) 1997-01-28
CA2176511C (fr) 2007-01-09
HU225616B1 (en) 2007-05-02
CN1136316A (zh) 1996-11-20
CZ145996A3 (en) 1997-02-12
BR9506389A (pt) 1997-09-16
FR2725207B1 (fr) 1996-11-29
HU9601250D0 (en) 1996-07-29
FR2725207A1 (fr) 1996-04-05
MX9602027A (es) 1998-01-31
AU694270B2 (en) 1998-07-16
BR9506389B1 (pt) 2009-08-11
EP0737200B1 (fr) 2002-06-12
DE69527037D1 (de) 2002-07-18
JP4194115B2 (ja) 2008-12-10
US6211393B1 (en) 2001-04-03
AU3611295A (en) 1996-04-26
BRPI9506389B8 (pt) 2015-12-08
CA2176511A1 (fr) 1996-04-11
JPH09505835A (ja) 1997-06-10
EP0737200A1 (fr) 1996-10-16
WO1996010575A1 (fr) 1996-04-11
CZ296973B6 (cs) 2006-08-16
DE69527037T2 (de) 2003-01-30

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