ES2174748B1 - Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos. - Google Patents
Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos.Info
- Publication number
- ES2174748B1 ES2174748B1 ES200100273A ES200100273A ES2174748B1 ES 2174748 B1 ES2174748 B1 ES 2174748B1 ES 200100273 A ES200100273 A ES 200100273A ES 200100273 A ES200100273 A ES 200100273A ES 2174748 B1 ES2174748 B1 ES 2174748B1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- new salt
- tiazolidindiona
- polymorphes
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 239000003472 antidiabetic agent Substances 0.000 title abstract 2
- 229940125708 antidiabetic agent Drugs 0.000 title abstract 2
- ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 abstract 2
- 229940123464 Thiazolidinedione Drugs 0.000 abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 201000001421 hyperglycemia Diseases 0.000 abstract 1
- 230000002218 hypoglycaemic effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabéticos y procedimiento para la obtención de los mismos. Se refiere a una nueva sal de tiazolidindiona y a sus polimorfos que presentan una actividad hipoglucemiante elevada y, que por lo tanto, son potencialmente útiles en el tratamiento y/o profilaxis de la diabetes y/o otras alteraciones o complicaciones propias de la diabetes como hiperglicemia o hiperlipidemia. También se refiere a un procedimiento para la obtención de los mismos.
Priority Applications (27)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200100273A ES2174748B1 (es) | 2001-01-31 | 2001-01-31 | Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos. |
NZ527677A NZ527677A (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
SK955-2003A SK9552003A3 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
EEP200300356A EE200300356A (et) | 2001-01-31 | 2002-01-21 | Tiasolidiindiooni sool ja selle polümorfid kui diabeedivastased ained ning nende valmistamise meetod |
MXPA03006722A MXPA03006722A (es) | 2001-01-31 | 2002-01-21 | Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y metodo para la obtencion de los mismos. |
CNA028043863A CN1694881A (zh) | 2001-01-31 | 2002-01-21 | 新的用作抗糖尿病药的噻唑烷二酮的盐和它的多晶型物以及获得它们的方法 |
CZ20032015A CZ20032015A3 (cs) | 2001-01-31 | 2002-01-21 | Nová sůl thiazolidindionu a její polymorfy jako antidiabetická činidla a metoda jejich získávání |
APAP/P/2003/002832A AP1281A (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and methods for obtaining them. |
JP2002561467A JP2004529870A (ja) | 2001-01-31 | 2002-01-21 | 抗糖尿病薬としてのチアゾリジンジオンの新規塩およびその多形体ならびにその製造方法 |
PCT/IB2002/000229 WO2002060899A1 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
BR0206850-8A BR0206850A (pt) | 2001-01-31 | 2002-01-21 | Sal de tiazolidinadiona e seus polimorfos como agentes antidiabéticos e método pata obtê-los |
HU0302871A HUP0302871A2 (hu) | 2001-01-31 | 2002-01-21 | Tiazolidindion és polimorf módosulatai új sója, eljárás előállítására, ezeket tartalmazó diabetes elleni szerek |
PL02362527A PL362527A1 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
EA200300842A EA200300842A1 (ru) | 2001-01-31 | 2002-01-21 | Новая соль тиазолидиндиона и ее полиморфные формы в качестве противодиабетических средств и способ их получения |
EP02716216A EP1355908A1 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
YU60303A YU60303A (sh) | 2001-01-31 | 2002-01-21 | Nova so tiazolidindiona i njeni polimorfni oblici kao antidijabetički agensi i postupak za njihovo dobijanje |
ZA200305873A ZA200305873B (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as anti-diabetic agents and method for obtaining them. |
CA002436556A CA2436556A1 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
KR10-2003-7009880A KR20030078893A (ko) | 2001-01-31 | 2002-01-21 | 항당뇨병제로서 티아졸리딘디온의 신규한 염 및 이의동질이상체 및 이들을 수득하는 방법 |
IL15702802A IL157028A0 (en) | 2001-01-31 | 2002-01-21 | New salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
US10/470,980 US20040106632A1 (en) | 2001-01-31 | 2002-01-21 | Salt of thiazolidinedione and its polymorphs as antidiabetic agents and method for obtaining them |
PE2002000054A PE20020969A1 (es) | 2001-01-31 | 2002-01-24 | Sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos |
ARP020100291A AR042584A1 (es) | 2001-01-31 | 2002-01-28 | Sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos |
NO20033375A NO20033375L (no) | 2001-01-31 | 2003-07-28 | Nye salter av tiazolidindion og dets polymorfer som antidiabetiske midler og fremgangsmåter for å oppnå dem |
IS6896A IS6896A (is) | 2001-01-31 | 2003-07-28 | Nýtt salt þíasólidíndíóns og fjölgervingar þess sem andsykursýkismiðlar og aðferð til að öðlast þá |
MA27262A MA26988A1 (fr) | 2001-01-31 | 2003-07-31 | Nouveau sel de la thiazolidinedione et ses varietes polymorphiques en tant qu'agents antidiabetiques et methode pour les obtenir. |
BG108047A BG108047A (bg) | 2001-01-31 | 2003-08-01 | Нова 'ол на 'иазолидиндион и н...йни полимор"и ка'о про'иводиаб...'и-ни 'р...д''ва и м...'од за пол"-аван...'о им |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200100273A ES2174748B1 (es) | 2001-01-31 | 2001-01-31 | Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2174748A1 ES2174748A1 (es) | 2002-11-01 |
ES2174748B1 true ES2174748B1 (es) | 2003-09-16 |
Family
ID=8496644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES200100273A Expired - Fee Related ES2174748B1 (es) | 2001-01-31 | 2001-01-31 | Nueva sal de tiazolidindiona y sus polimorfos como agentes antidiabeticos y procedimiento para la obtencion de los mismos. |
Country Status (27)
Country | Link |
---|---|
US (1) | US20040106632A1 (es) |
EP (1) | EP1355908A1 (es) |
JP (1) | JP2004529870A (es) |
KR (1) | KR20030078893A (es) |
CN (1) | CN1694881A (es) |
AP (1) | AP1281A (es) |
AR (1) | AR042584A1 (es) |
BG (1) | BG108047A (es) |
BR (1) | BR0206850A (es) |
CA (1) | CA2436556A1 (es) |
CZ (1) | CZ20032015A3 (es) |
EA (1) | EA200300842A1 (es) |
EE (1) | EE200300356A (es) |
ES (1) | ES2174748B1 (es) |
HU (1) | HUP0302871A2 (es) |
IL (1) | IL157028A0 (es) |
IS (1) | IS6896A (es) |
MA (1) | MA26988A1 (es) |
MX (1) | MXPA03006722A (es) |
NO (1) | NO20033375L (es) |
NZ (1) | NZ527677A (es) |
PE (1) | PE20020969A1 (es) |
PL (1) | PL362527A1 (es) |
SK (1) | SK9552003A3 (es) |
WO (1) | WO2002060899A1 (es) |
YU (1) | YU60303A (es) |
ZA (1) | ZA200305873B (es) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2137915T3 (es) * | 1987-09-04 | 2000-01-01 | Beecham Group Plc | Derivados de tiazolidindiona sustituida. |
CN1183130C (zh) * | 1999-09-24 | 2005-01-05 | 中国人民解放军军事医学科学院毒物药物研究所 | 噻唑烷类衍生物及其医药用途 |
ES2156574B1 (es) * | 1999-11-18 | 2002-02-01 | Vita Invest Sa | Nuevos derivados de tiazolidindiona como agentes antidiabeticos |
-
2001
- 2001-01-31 ES ES200100273A patent/ES2174748B1/es not_active Expired - Fee Related
-
2002
- 2002-01-21 JP JP2002561467A patent/JP2004529870A/ja active Pending
- 2002-01-21 ZA ZA200305873A patent/ZA200305873B/en unknown
- 2002-01-21 PL PL02362527A patent/PL362527A1/xx not_active Application Discontinuation
- 2002-01-21 CN CNA028043863A patent/CN1694881A/zh active Pending
- 2002-01-21 EP EP02716216A patent/EP1355908A1/en not_active Withdrawn
- 2002-01-21 CA CA002436556A patent/CA2436556A1/en not_active Abandoned
- 2002-01-21 HU HU0302871A patent/HUP0302871A2/hu unknown
- 2002-01-21 IL IL15702802A patent/IL157028A0/xx unknown
- 2002-01-21 NZ NZ527677A patent/NZ527677A/en unknown
- 2002-01-21 MX MXPA03006722A patent/MXPA03006722A/es not_active Application Discontinuation
- 2002-01-21 YU YU60303A patent/YU60303A/sh unknown
- 2002-01-21 US US10/470,980 patent/US20040106632A1/en not_active Abandoned
- 2002-01-21 WO PCT/IB2002/000229 patent/WO2002060899A1/en not_active Application Discontinuation
- 2002-01-21 EA EA200300842A patent/EA200300842A1/ru unknown
- 2002-01-21 AP APAP/P/2003/002832A patent/AP1281A/en active
- 2002-01-21 EE EEP200300356A patent/EE200300356A/xx unknown
- 2002-01-21 SK SK955-2003A patent/SK9552003A3/sk not_active Application Discontinuation
- 2002-01-21 BR BR0206850-8A patent/BR0206850A/pt not_active IP Right Cessation
- 2002-01-21 CZ CZ20032015A patent/CZ20032015A3/cs unknown
- 2002-01-21 KR KR10-2003-7009880A patent/KR20030078893A/ko not_active Application Discontinuation
- 2002-01-24 PE PE2002000054A patent/PE20020969A1/es not_active Application Discontinuation
- 2002-01-28 AR ARP020100291A patent/AR042584A1/es not_active Application Discontinuation
-
2003
- 2003-07-28 IS IS6896A patent/IS6896A/is unknown
- 2003-07-28 NO NO20033375A patent/NO20033375L/no not_active Application Discontinuation
- 2003-07-31 MA MA27262A patent/MA26988A1/fr unknown
- 2003-08-01 BG BG108047A patent/BG108047A/bg unknown
Also Published As
Publication number | Publication date |
---|---|
ES2174748A1 (es) | 2002-11-01 |
EA200300842A1 (ru) | 2004-04-29 |
SK9552003A3 (en) | 2004-05-04 |
EP1355908A1 (en) | 2003-10-29 |
PL362527A1 (en) | 2004-11-02 |
CA2436556A1 (en) | 2002-08-08 |
EE200300356A (et) | 2003-10-15 |
NO20033375D0 (no) | 2003-07-28 |
KR20030078893A (ko) | 2003-10-08 |
JP2004529870A (ja) | 2004-09-30 |
HUP0302871A2 (hu) | 2003-12-29 |
YU60303A (sh) | 2006-05-25 |
IL157028A0 (en) | 2004-02-08 |
NZ527677A (en) | 2005-01-28 |
CN1694881A (zh) | 2005-11-09 |
AR042584A1 (es) | 2005-06-29 |
AP1281A (en) | 2004-05-25 |
MXPA03006722A (es) | 2004-10-15 |
MA26988A1 (fr) | 2004-12-20 |
US20040106632A1 (en) | 2004-06-03 |
CZ20032015A3 (cs) | 2004-02-18 |
PE20020969A1 (es) | 2002-12-04 |
IS6896A (is) | 2003-07-28 |
NO20033375L (no) | 2003-08-22 |
WO2002060899A1 (en) | 2002-08-08 |
BG108047A (bg) | 2004-08-31 |
ZA200305873B (en) | 2004-07-30 |
AP2003002832A0 (en) | 2003-09-30 |
BR0206850A (pt) | 2004-01-13 |
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