ES2173460T3 - Procedimiento de hirogenacion asimetrica de un compuesto atomico y derivado. - Google Patents

Procedimiento de hirogenacion asimetrica de un compuesto atomico y derivado.

Info

Publication number
ES2173460T3
ES2173460T3 ES97930607T ES97930607T ES2173460T3 ES 2173460 T3 ES2173460 T3 ES 2173460T3 ES 97930607 T ES97930607 T ES 97930607T ES 97930607 T ES97930607 T ES 97930607T ES 2173460 T3 ES2173460 T3 ES 2173460T3
Authority
ES
Spain
Prior art keywords
pct
asymmetric
asymmetric hydrogenation
derivative
hyrogenation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97930607T
Other languages
English (en)
Inventor
Francois Mathey
Frederic Robin
Francois Mercier
Michel Spagnol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhodia Chimie SAS
Original Assignee
Rhodia Chimie SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia Chimie SAS filed Critical Rhodia Chimie SAS
Application granted granted Critical
Publication of ES2173460T3 publication Critical patent/ES2173460T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROCEDIMIENTO DE HIDROGENACION ASIMETRICA DE UN COMPUESTO CETONICO Y DERIVADO. LA INVENCION SE REFIERE A LA UTILIZACION DE COMPLEJOS METALICOS OPTICAMENTE ACTIVOS COMO CATALIZADORES DE HIDROGENACION ASIMETRICA DE UN COMPUESTO CETONICO Y DERIVADO. EL PROCEDIMIENTO DE HIDROGENACION ASIMETRICA DE UN COMPUESTO CETONICO Y DERIVADO SEGUN LA INVENCION SE CARACTERIZA PORQUE SE EFECTUA LA HIDROGENACION ASIMETRICA DE DICHO COMPUESTO EN PRESENCIA DE UNA CANTIDAD EFICAZ DE UN COMPLEJO METALICO QUE COMPRENDE, COMO AGLUTINANDO, UNA DIFOSFINA OPTICAMENTE ACTIVA QUE RESPONDE A UNA DE LAS FORMULAS: (A) O (B).
ES97930607T 1996-06-28 1997-06-27 Procedimiento de hirogenacion asimetrica de un compuesto atomico y derivado. Expired - Lifetime ES2173460T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9608060A FR2750423B1 (fr) 1996-06-28 1996-06-28 Procede d'hydrogenation asymetrique d'un compose cetonique

Publications (1)

Publication Number Publication Date
ES2173460T3 true ES2173460T3 (es) 2002-10-16

Family

ID=9493517

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97930607T Expired - Lifetime ES2173460T3 (es) 1996-06-28 1997-06-27 Procedimiento de hirogenacion asimetrica de un compuesto atomico y derivado.

Country Status (9)

Country Link
US (1) US6166257A (es)
EP (1) EP0912467B1 (es)
JP (1) JP2000513370A (es)
AT (1) ATE216690T1 (es)
DE (1) DE69712204T2 (es)
ES (1) ES2173460T3 (es)
FR (1) FR2750423B1 (es)
NO (1) NO312363B1 (es)
WO (1) WO1998000375A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6743921B2 (en) * 2002-01-24 2004-06-01 Dsm Catalytica Pharmaceuticals, Inc. Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl-piperidin-1-yl)-1-propanol compounds
US20040030199A1 (en) * 2002-01-29 2004-02-12 Maughon Robert R. Process for reducing alpha-haloketones to secondary alpha-haloalcohols
PL2361924T3 (pl) 2004-09-09 2014-08-29 Teva Pharma Proces przygotowania mieszanin octanu trifluoroacetyloglatirameru z zastosowaniem oczyszczonego kwasu bromowodorowego
EP2009776A1 (en) * 2007-06-26 2008-12-31 Austriamicrosystems AG Buck-boost switching regulator and method thereof
UA100732C2 (ru) * 2008-04-17 2013-01-25 Юнайтед Фосфорус Лімітед Гидрирование иминов
US8461357B2 (en) 2008-09-19 2013-06-11 Uti Limited Partnership Expeditious synthesis of gibberellin A5 and esters thereof
BR112012016059A2 (pt) 2009-12-29 2015-09-01 Mapi Pharma Ltd "compostos intermediários e processos para a preparação de tapentadol e compostos relacionados".
US9614443B2 (en) 2014-07-24 2017-04-04 Qorvo Us, Inc. Smooth transitioning buck-boost DC-DC converter
WO2018017589A1 (en) * 2016-07-19 2018-01-25 The General Hospital Corporation Compounds for targeting cancer stem cells

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758107A (nl) * 1969-11-05 1971-04-28 Shell Int Research Werkwijze ter bereiding van 9-carboxymethyl- 9- fosfabicyclononanen en alkalimetaalzouten daarvan
US4996361A (en) * 1987-07-30 1991-02-26 The University Of British Columbia Process for the preparation of optically active secondary arylamines
DE4001019A1 (de) * 1990-01-16 1991-07-18 Degussa Verfahren zur asymmetrischen hydrierung von (alpha)-ketocarbonylverbindungen zu optisch aktiven (alpha)-hydroxycarbonylverbindungen
US5250731A (en) * 1992-03-17 1993-10-05 E. I. Du Pont De Nemours And Company Preparation of optically active hydrazines and amines
FR2693190B1 (fr) * 1992-07-02 1994-09-23 Elf Aquitaine Procédé d'hydrogénation énantiosélectif de la double liaison C=O OXO.
ES2130321T3 (es) * 1993-10-08 1999-07-01 Hoffmann La Roche Compuestos de fosforo opticamente activos.
BR9505836A (pt) * 1994-02-02 1996-02-27 Ciba Geigy Ag Processo para a hidrogenaçao de iminas
ES2158147T3 (es) * 1994-12-28 2001-09-01 Rhodia Chimie Sa Difosfinas opticamente activas, y su preparacion por desdoblamiento de mezclas racemicas.
DE19620023C2 (de) * 1996-05-17 2001-03-08 Celanese Chem Europe Gmbh Verfahren zur Herstellung von Phosphinat- oder Phosphonatgruppen enthaltenden tertiären Phosphanen und neue Phosphinatgruppen enthaltende tertiäre Phosphane
WO1997018894A1 (fr) * 1995-11-22 1997-05-29 Firmenich S.A. Catalyseurs de ruthenium et leur utilisation dans l'hydrogenation asymetrique de cyclopentenones

Also Published As

Publication number Publication date
JP2000513370A (ja) 2000-10-10
DE69712204D1 (de) 2002-05-29
ATE216690T1 (de) 2002-05-15
WO1998000375A1 (fr) 1998-01-08
FR2750423B1 (fr) 1998-08-14
NO312363B1 (no) 2002-04-29
EP0912467B1 (fr) 2002-04-24
DE69712204T2 (de) 2002-11-21
FR2750423A1 (fr) 1998-01-02
NO986124L (no) 1999-03-01
NO986124D0 (no) 1998-12-23
US6166257A (en) 2000-12-26
EP0912467A1 (fr) 1999-05-06

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