ES2173096T3 - Composicion farmaceutica peletizada. - Google Patents
Composicion farmaceutica peletizada.Info
- Publication number
- ES2173096T3 ES2173096T3 ES93915549T ES93915549T ES2173096T3 ES 2173096 T3 ES2173096 T3 ES 2173096T3 ES 93915549 T ES93915549 T ES 93915549T ES 93915549 T ES93915549 T ES 93915549T ES 2173096 T3 ES2173096 T3 ES 2173096T3
- Authority
- ES
- Spain
- Prior art keywords
- weight
- approximately
- core
- active ingredient
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
UNA COMPOSICION FARMACEUTICA EN FORMA DE PASTILLA DE LIBERACION SOSTENIDA QUE CONTIENE UN ELEMENTO NUCLEO QUE INCLUYE APROXIMADAMENTE DE UN 0,1 A UN 95% EN PESO, EN BASE AL PESO TOTAL DEL ELEMENTO NUCLEO, DE UN INGREDIENTE ACTIVO DE BAJA SOLUBILIDAD ACUOSA, APROXIMADAMENTE DE UN 0,1 A UN 55% EN PESO DE UN AGENTE AGLUTINANTE; APROXIMADAMENTE DE UN 5 A UN 99% EN PESO DE UNA SEMILLA NUCLEO; Y UN REVESTIMIENTO NUCLEO, PARA EL ELEMENTO NUCLEO, QUE INCLUYE APROXIMADAMENTE DE UN 30 A UN 97% EN PESO, EN BASE AL PESO TOTAL DE REVESTIMIENTO NUCLEO, EXCLUIDA LA SUSTANCIA DE RELLENO, DE UN POLIMERO ENTERICO; APROXIMADAMENTE DE UN 3 A UN 50% EN PESO DE UN POLIMERO INSOLUBLE; Y DE UN 0 A UN 50% APROXIMADAMENTE EN PESO DE UN PLASTIFICANTE, EN DONDE EL POLIMERO ENTERICO CONTIENE AL MENOS UN 70% EN PESO APROXIMADAMENTE DEL PESO TOTAL DEL POLIMERO ENTERICO Y EL POLIMERO INSOLUBLE; Y EL REVESTIMIENTO NUCLEO ES TAL QUE EL INGREDIENTE ACTIVO SE LIBERA DE FORMA CONTROLADA DURANTE UN PERIODO DE TIEMPO PROLONGADOEN EL INTESTINO PERO NO SE LIBERA SUSTANCIALMENTE EN EL ENTORNO ACIDO DEL ESTOMAGO Y LOS NIVELES EN SANGRE DEL INGREDIENTE ACTIVO SE MANTIENEN DENTRO A NIVEL TERAPEUTICO DURANTE UN MAYOR PERIODO DE TIEMPO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPL392192 | 1992-08-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2173096T3 true ES2173096T3 (es) | 2002-10-16 |
Family
ID=3776337
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93915549T Expired - Lifetime ES2173096T3 (es) | 1992-08-05 | 1993-07-23 | Composicion farmaceutica peletizada. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5800836A (es) |
EP (1) | EP0653935B1 (es) |
JP (1) | JPH07509702A (es) |
AT (1) | ATE217188T1 (es) |
CA (1) | CA2141582C (es) |
DE (1) | DE69331906T2 (es) |
ES (1) | ES2173096T3 (es) |
NZ (1) | NZ253999A (es) |
SG (1) | SG42869A1 (es) |
WO (1) | WO1994003160A1 (es) |
ZA (1) | ZA935650B (es) |
Families Citing this family (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5681585A (en) * | 1991-12-24 | 1997-10-28 | Euro-Celtique, S.A. | Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer |
US5968551A (en) | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
US5958459A (en) * | 1991-12-24 | 1999-09-28 | Purdue Pharma L.P. | Opioid formulations having extended controlled released |
EP0653935B1 (en) * | 1992-08-05 | 2002-05-08 | F.H. FAULDING & CO. LIMITED | Pelletised pharmaceutical composition |
EP0689840A1 (de) * | 1994-06-28 | 1996-01-03 | Spirig Ag Pharmazeutische Präparate | Neues orales Erythromycinbase enthaltendes Arzneimittel |
CZ289804B6 (cs) * | 1994-07-08 | 2002-04-17 | Astrazeneca Ab | Multijednotková tabletovaná dávková forma I |
SE9500422D0 (sv) * | 1995-02-06 | 1995-02-06 | Astra Ab | New oral pharmaceutical dosage forms |
GB9519363D0 (en) | 1995-09-22 | 1995-11-22 | Euro Celtique Sa | Pharmaceutical formulation |
SE9600071D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients I |
SE9600070D0 (sv) | 1996-01-08 | 1996-01-08 | Astra Ab | New oral pharmaceutical dosage forms |
SE9600072D0 (sv) * | 1996-01-08 | 1996-01-08 | Astra Ab | New oral formulation of two active ingredients II |
SE512835C2 (sv) * | 1996-01-08 | 2000-05-22 | Astrazeneca Ab | Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare |
US6974595B1 (en) | 1996-05-17 | 2005-12-13 | Proethic Pharmaceuticals, Inc. | Pharmaceutical compositions based on Diclofenae |
US7687542B2 (en) | 1996-05-17 | 2010-03-30 | Kowa Pharmaeuticals America, Inc. | Rapidly bioavailable tablet and capsule formulations of diclofenac |
US6312724B1 (en) | 1997-04-04 | 2001-11-06 | Isa Odidi | Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof |
DE19715594A1 (de) | 1997-04-15 | 1998-10-22 | Bayer Ag | Analgetika-Kombination |
DE19728249C2 (de) * | 1997-07-02 | 2001-05-03 | Georgios Pandalis | Produkt aus einem Kern und mindestens einer ein Naturharz enthaltenden Umhüllung, Steckkapsel, Verfahren zur Herstellung einer Filmtablette, Weichkapsel, Steckkapsel und Verwendung von Naturharzen |
BR9911031A (pt) | 1998-05-20 | 2002-01-29 | Liposome Co Inc | Novas formulações em partìculas |
UA69413C2 (uk) | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
US7122207B2 (en) | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
UA73092C2 (uk) | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Таблетка з ентеросолюбільним покриттям і спосіб її приготування |
JP2000095709A (ja) * | 1998-09-25 | 2000-04-04 | Shin Etsu Chem Co Ltd | 水系コーティング剤及び固形医薬製剤の製造方法 |
US20010055613A1 (en) | 1998-10-21 | 2001-12-27 | Beth A. Burnside | Oral pulsed dose drug delivery system |
US8545880B2 (en) * | 1999-02-26 | 2013-10-01 | Andrx Pharmaceuticals, Llc | Controlled release oral dosage form |
US6245913B1 (en) | 1999-06-30 | 2001-06-12 | Wockhardt Europe Limited | Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole |
CA2277407A1 (en) * | 1999-07-14 | 2001-01-14 | Bernard Charles Sherman | Pharmaceutical tablet comprising an nsaid and misoprostol |
US6475493B1 (en) | 1999-09-02 | 2002-11-05 | Norstrum Pharmaceuticals, Inc. | Controlled release pellet formulation |
US20020102309A1 (en) * | 1999-09-14 | 2002-08-01 | Jane C. I. Hirsh | Controlled release formulation for administration of an anti-inflammatory naphthalene derivative |
BRPI0015284B8 (pt) | 1999-10-29 | 2021-05-25 | Euro Celtique S/A | formulações de hidrocodona de liberação controlada |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
GB0000482D0 (en) * | 2000-01-11 | 2000-03-01 | Norton Healthcare Ltd | Enteric coated pharmaceutical formulation |
US8088060B2 (en) | 2000-03-15 | 2012-01-03 | Orbusneich Medical, Inc. | Progenitor endothelial cell capturing with a drug eluting implantable medical device |
US9522217B2 (en) | 2000-03-15 | 2016-12-20 | Orbusneich Medical, Inc. | Medical device with coating for capturing genetically-altered cells and methods for using same |
KR101045144B1 (ko) | 2000-10-30 | 2011-06-30 | 유로-셀티크 소시에떼 아노뉨 | 서방성 하이드로코돈 제형 |
CA2796884A1 (en) * | 2001-02-08 | 2002-08-15 | Andrx Pharmaceuticals, Inc. | Improved controlled release oral dosage form |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
US20030032675A1 (en) * | 2001-02-15 | 2003-02-13 | Franz G. Andrew | Manufacture of thyroid hormone tablets having consistent active moiety amounts |
JP2004525109A (ja) * | 2001-02-15 | 2004-08-19 | キング・ファーマシューティカルズ・インコーポレイティッド | 安定化された甲状腺ホルモン医薬組成物、及びその製法 |
US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
US20030072731A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing starch or dextrin |
US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
US20030198667A1 (en) * | 2001-08-10 | 2003-10-23 | Franz Andrew G. | Methods of producing dispersible pharmaceutical compositions |
US20030180353A1 (en) * | 2001-08-10 | 2003-09-25 | Franz G. Andrew | Stabilized pharmaceutical compositions |
US20030190349A1 (en) * | 2001-08-10 | 2003-10-09 | Franz G. Andrew | Methods of stabilizing pharmaceutical compositions |
US20030198671A1 (en) * | 2001-08-10 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique plasma AUC properties |
US20030203967A1 (en) * | 2001-08-14 | 2003-10-30 | Franz G. Andrew | Levothyroxine compositions having unique Tmax properties |
US20030198672A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique triidothyronine plasma AUC properties |
US7101569B2 (en) * | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
US20030195253A1 (en) * | 2001-08-14 | 2003-10-16 | Franz G. Andrew | Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration |
US8309118B2 (en) | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
US20030175337A1 (en) * | 2001-10-29 | 2003-09-18 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
US20030181488A1 (en) * | 2002-03-07 | 2003-09-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Administration form for the oral application of 3-[(2-{[4-(hexyloxycarbonylamino-imino-methyl)-phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionic acid ethyl ester and the salts thereof |
US6958161B2 (en) * | 2002-04-12 | 2005-10-25 | F H Faulding & Co Limited | Modified release coated drug preparation |
EP2422775A3 (en) | 2002-09-20 | 2012-04-18 | Alpharma, Inc. | Sequestering subunit and related compositions and methods |
US6913768B2 (en) * | 2002-09-24 | 2005-07-05 | Shire Laboratories, Inc. | Sustained release delivery of amphetamine salts |
CA2803922C (en) * | 2003-04-07 | 2015-09-15 | Supernus Pharmaceuticals, Inc. | Once daily formulations of tetracyclines |
CA2529429C (en) | 2003-06-17 | 2009-10-20 | Filtertek Inc. | Fluid handling device and method of making same |
DE10339862A1 (de) * | 2003-08-29 | 2005-03-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-[(2-{[4-(Hexyloxycarbonylamino-imino-methyl)- phenylamino]-methyl}-1-methyl-1H-benzimidazol-5-carbonyl)-pyridin-2-yl-amino]-propionsäure-ethylester-Methansulfonat und dessen Verwendung als Arzneimittel |
DE102004027924A1 (de) * | 2004-06-09 | 2005-12-29 | Röhm GmbH & Co. KG | Arzneiform, enthaltend den Wirkstoff Cholylsarcosin |
JO3352B1 (ar) | 2005-06-17 | 2019-03-13 | Apr Applied Pharma Res Sa | صيغ دايكلوفيناك وطرق استخدامه |
US7544373B2 (en) * | 2007-04-02 | 2009-06-09 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
US7919483B2 (en) * | 2005-06-24 | 2011-04-05 | Medicis Pharmaceutical Corporation | Method for the treatment of acne |
US8252776B2 (en) | 2007-04-02 | 2012-08-28 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
US8722650B1 (en) | 2005-06-24 | 2014-05-13 | Medicis Pharmaceutical Corporation | Extended-release minocycline dosage forms |
US20080241235A1 (en) * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
US20080242642A1 (en) | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline oral dosage forms for the treatment of acne |
US7541347B2 (en) * | 2007-04-02 | 2009-06-02 | Medicis Pharmaceutical Coropration | Minocycline oral dosage forms for the treatment of acne |
US7939561B2 (en) | 2006-02-07 | 2011-05-10 | Apr Applied Pharma Research S.A. | Blister packaging for acute pain regimens |
US7700125B2 (en) | 2006-02-07 | 2010-04-20 | Kowa Pharmaceuticals America, Inc. | Moisture resistant container systems for rapidly bioavailable dosage forms |
CA2655835C (en) | 2006-06-19 | 2015-07-21 | Alpharma, Inc. | Abuse-resistant pharmaceutical compositions of opioid agonists |
EP2073797A2 (en) * | 2006-10-11 | 2009-07-01 | Alpharma, Inc. | Pharmaceutical compositions |
US20080241197A1 (en) * | 2007-04-02 | 2008-10-02 | Medicis Pharmaceutical Corporation | Minocycline dosage forms for the treatment of acne |
US8623418B2 (en) | 2007-12-17 | 2014-01-07 | Alpharma Pharmaceuticals Llc | Pharmaceutical composition |
FR2930147B1 (fr) * | 2008-04-18 | 2013-02-08 | Flamel Tech Sa | Forme orale solide dotee d'un double profil de liberation |
US20100021549A1 (en) * | 2008-07-28 | 2010-01-28 | Flamel Technologies, S.A. | Microparticle oral form useful for the modified release of nanoparticles |
WO2010017310A1 (en) | 2008-08-06 | 2010-02-11 | Medicis Pharmaceutical Corporation | Method for the treatment of acne and certain dosage forms thereof |
US20100285125A1 (en) * | 2009-05-07 | 2010-11-11 | Padma Venkitachalam Devarajan | Delivery system for poorly soluble drugs |
FR2945947B1 (fr) * | 2009-05-29 | 2011-07-29 | Flamel Tech Sa | Compositions pharmaceutiques flottantes a liberation controlee |
GB0909243D0 (en) * | 2009-05-29 | 2009-07-15 | Univ Dundee | Angina treatment |
US9561241B1 (en) | 2011-06-28 | 2017-02-07 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for minocycline |
BR112014023278B1 (pt) | 2012-03-20 | 2021-11-16 | Laboratorios Bagó S.A. | Método para produção de microcápsulas de alginato de cálcio entéricas e composição farmacêutica em multipartícula oral |
CN103349648B (zh) * | 2013-07-22 | 2015-03-25 | 南通广泰生化制品有限公司 | 枸橼酸他莫昔芬肠溶片 |
CN103393604B (zh) * | 2013-07-22 | 2015-04-01 | 南通广泰生化制品有限公司 | 枸橼酸他莫昔芬肠溶颗粒 |
JP7147523B2 (ja) * | 2018-12-06 | 2022-10-05 | 三生医薬株式会社 | 造粒方法 |
EP4037666B1 (en) | 2020-12-08 | 2024-05-01 | Ruminant Biotech Corp Limited | Improvements to devices and methods for delivery of substances to animals |
WO2023044024A1 (en) * | 2021-09-17 | 2023-03-23 | Novelstar Pharmaceuticals Inc. | Novel ph dependent coating drug delivery system |
Family Cites Families (22)
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---|---|---|---|---|
AU477515B2 (en) * | 1973-01-17 | 1975-07-17 | Sterling Pharmaceuticals Pty. Limited | Enteric coating |
JPS5518694B2 (es) * | 1973-04-02 | 1980-05-21 | ||
DE2327629A1 (de) * | 1973-05-30 | 1974-12-12 | Siemens Ag | Durchfuehrungsisolator fuer hochspannungseinrichtungen und verfahren zu seiner herstellung |
DE2336218C3 (de) * | 1973-07-17 | 1985-11-14 | Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz | Orale Arzneiform |
DE3000979A1 (de) * | 1980-01-12 | 1981-07-23 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue dipyridamol-retardformen und verfahren zu ihrer herstellung |
JPS5867616A (ja) * | 1981-10-15 | 1983-04-22 | Tanabe Seiyaku Co Ltd | 腸溶性マイクロカプセル |
JPS5910512A (ja) * | 1982-07-09 | 1984-01-20 | Tanabe Seiyaku Co Ltd | 徐放性マイクロカプセルおよびその製法 |
GB2132887A (en) * | 1982-11-15 | 1984-07-18 | Procter & Gamble | Enteric-coated anti-inflammatory compositions |
WO1986000306A1 (en) * | 1982-12-29 | 1986-01-16 | Sansho Seiyaku Co., Ltd. | Kojic acid derivatives and whitening cosmetics containing same |
SE457505B (sv) * | 1984-01-10 | 1989-01-09 | Lejus Medical Ab | Laminatbelagd oral farmaceutisk komposition och foerfarande foer dess framstaellning |
US4751226A (en) * | 1985-09-12 | 1988-06-14 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazoloisoquinoline derivatives, plant growth regulating compositions, and method of use therefor |
JPS62135419A (ja) * | 1985-12-06 | 1987-06-18 | Ikeda Mohandou:Kk | ジクロフエナク塩の粒状組成物及びその製造法 |
AU591248B2 (en) * | 1986-03-27 | 1989-11-30 | Kinaform Technology, Inc. | Sustained-release pharaceutical preparation |
SE460946B (sv) * | 1987-03-16 | 1989-12-11 | Lejus Medical Ab | En multipel-unit-dos komposition av kinidinglukonat |
SE509029C2 (sv) * | 1988-08-16 | 1998-11-30 | Ss Pharmaceutical Co | Långtidsverkande diklofenak-natriumpreparat |
US5026559A (en) * | 1989-04-03 | 1991-06-25 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
WO1991000688A1 (en) * | 1989-07-07 | 1991-01-24 | Vsesojuzny Nauchno-Issledovatelsky Institut Selskokhozyaistvennoi Biotekhnologii | Method for sterilization of plant anthers |
US5084287A (en) * | 1990-03-15 | 1992-01-28 | Warner-Lambert Company | Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat |
IT1246382B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
EP0520119A1 (de) * | 1991-06-17 | 1992-12-30 | Spirig Ag Pharmazeutische Präparate | Neue orale Diclofenaczubereitung |
EP0653935B1 (en) * | 1992-08-05 | 2002-05-08 | F.H. FAULDING & CO. LIMITED | Pelletised pharmaceutical composition |
DE19545702C2 (de) * | 1995-12-07 | 1999-05-12 | Horsch Maschinen Gmbh | Werkzeuganordnung für Bodenbearbeitungsgeräte |
-
1993
- 1993-07-23 EP EP93915549A patent/EP0653935B1/en not_active Expired - Lifetime
- 1993-07-23 ES ES93915549T patent/ES2173096T3/es not_active Expired - Lifetime
- 1993-07-23 JP JP6504817A patent/JPH07509702A/ja active Pending
- 1993-07-23 DE DE69331906T patent/DE69331906T2/de not_active Expired - Lifetime
- 1993-07-23 CA CA002141582A patent/CA2141582C/en not_active Expired - Lifetime
- 1993-07-23 WO PCT/AU1993/000371 patent/WO1994003160A1/en active IP Right Grant
- 1993-07-23 AT AT93915549T patent/ATE217188T1/de active
- 1993-07-23 SG SG1996000321A patent/SG42869A1/en unknown
- 1993-07-23 NZ NZ253999A patent/NZ253999A/en not_active IP Right Cessation
- 1993-08-04 ZA ZA935650A patent/ZA935650B/xx unknown
-
1995
- 1995-02-06 US US08/398,744 patent/US5800836A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1994003160A1 (en) | 1994-02-17 |
US5800836A (en) | 1998-09-01 |
NZ253999A (en) | 1996-07-26 |
DE69331906T2 (de) | 2002-12-19 |
EP0653935A1 (en) | 1995-05-24 |
ZA935650B (en) | 1994-03-07 |
SG42869A1 (en) | 1997-10-17 |
CA2141582A1 (en) | 1994-02-17 |
ATE217188T1 (de) | 2002-05-15 |
EP0653935B1 (en) | 2002-05-08 |
JPH07509702A (ja) | 1995-10-26 |
DE69331906D1 (de) | 2002-06-13 |
EP0653935A4 (en) | 1995-06-07 |
CA2141582C (en) | 2003-09-30 |
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