ES2172944T3 - Forma de dosificacion osmotica que comprende un primer y un segundo revestimiento. - Google Patents
Forma de dosificacion osmotica que comprende un primer y un segundo revestimiento.Info
- Publication number
- ES2172944T3 ES2172944T3 ES98959576T ES98959576T ES2172944T3 ES 2172944 T3 ES2172944 T3 ES 2172944T3 ES 98959576 T ES98959576 T ES 98959576T ES 98959576 T ES98959576 T ES 98959576T ES 2172944 T3 ES2172944 T3 ES 2172944T3
- Authority
- ES
- Spain
- Prior art keywords
- dosage form
- coating
- osmotic dosage
- coat
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Materials For Medical Uses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
Forma de dosificación de liberación prolongada (10) que comprende: una composición de fármaco que comprende un fármaco (14) y un excipiente farmacéuticamente aceptable (18); un primer revestimiento (16) que rodea la composición de fármaco, comprendiendo el primer revestimiento (16) etilcelulosa e hidroxialquilcelulosa; un segundo revestimiento (12) que rodea el primer revestimiento (16), comprendiendo el segundo revestimiento (12) una composición permeable al paso de fluido e impermeable al paso de fármaco (14); y una vía de paso de salida (13) en el primer (16) y el segundo (12) revestimientos para la liberación de fármaco (14) a partir de la forma de dosificación (10) durante un periodo de tiempo prolongado.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6766997P | 1997-12-05 | 1997-12-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2172944T3 true ES2172944T3 (es) | 2002-10-01 |
Family
ID=22077577
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98959576T Expired - Lifetime ES2172944T3 (es) | 1997-12-05 | 1998-11-23 | Forma de dosificacion osmotica que comprende un primer y un segundo revestimiento. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6210712B1 (es) |
EP (1) | EP1035834B1 (es) |
AT (1) | ATE216220T1 (es) |
AU (1) | AU1534699A (es) |
DE (1) | DE69805001T2 (es) |
DK (1) | DK1035834T3 (es) |
ES (1) | ES2172944T3 (es) |
HK (1) | HK1031197A1 (es) |
PT (1) | PT1035834E (es) |
WO (1) | WO1999029297A1 (es) |
Families Citing this family (65)
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US5858401A (en) | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
US8524277B2 (en) | 1998-03-06 | 2013-09-03 | Alza Corporation | Extended release dosage form |
US20050048120A1 (en) * | 1998-11-04 | 2005-03-03 | Edgren David Emil | Dosage form comprising self-destructive membrane |
US20030027789A1 (en) * | 2000-01-14 | 2003-02-06 | Ippei Yamaoka | Inhibitors against sodium ion absorption, and preventive or therapeutic agents and foods containing the same |
US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
BR0212951A (pt) * | 2001-09-28 | 2004-10-26 | Mcneil Ppc Inc | Formas de dosagens compósitas |
CA2363053C (en) * | 2001-11-09 | 2011-01-25 | Bernard Charles Sherman | Clopidogrel bisulfate tablet formulation |
DE60220953T2 (de) * | 2002-04-04 | 2008-02-28 | Dr. Reddy's Laboratories Ltd. | Pharmazeutische zusammensetzungen enthaltend eine antihistaminische abschwellende arzneistoffkombination und ein verfahren zur herstellung davon |
AR039744A1 (es) * | 2002-06-26 | 2005-03-09 | Alza Corp | Metodos y formas de dosificacion para aumentar la solubilidad de las composiciones de farmacos para la administracion controlada |
EP1534238A1 (en) * | 2002-07-29 | 2005-06-01 | ALZA Corporation | Formulations and dosage forms for controlled delivery of topiramate |
US20050232995A1 (en) * | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
US20050208132A1 (en) * | 2002-07-29 | 2005-09-22 | Gayatri Sathyan | Methods and dosage forms for reducing side effects of benzisozazole derivatives |
US20070078513A1 (en) * | 2002-09-18 | 2007-04-05 | Medtronic Vascular, Inc. | Controllable drug releasing gradient coatings for medical devices |
US20040131672A1 (en) * | 2003-01-07 | 2004-07-08 | Nilobon Podhipleux | Direct compression pharmaceutical composition containing a pharmaceutically active ingredient with poor flowing properties |
SI21402A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska dru�ba d.d. | Obloženi delci in farmacevtske oblike |
FR2857263B1 (fr) * | 2003-07-09 | 2005-09-09 | Sanofi Synthelabo | Nouvelle composition pharmaceutique solide comprenant de l'amisulpride |
US7314640B2 (en) * | 2003-07-11 | 2008-01-01 | Mongkol Sriwongjanya | Formulation and process for drug loaded cores |
NZ527142A (en) * | 2003-07-23 | 2006-03-31 | Douglas Pharmaceuticals Ltd | A stable suspension formulation |
MXPA06001548A (es) * | 2003-08-06 | 2006-09-04 | Johnson & Johnson | Suministro uniforme de topiramato durante un periodo prolongado con formulaciones de dispersion. |
WO2005020957A2 (en) * | 2003-08-22 | 2005-03-10 | Alza Corporation | Stepwise delivery of topiramate over prolonged period of time |
WO2005020959A2 (en) * | 2003-09-02 | 2005-03-10 | Alza Corporation | Novel drug compositions and dosage forms of topiramate |
US20070065513A1 (en) * | 2003-10-31 | 2007-03-22 | Avi Avramoff | Stable lansoprazole formulation |
AU2004308973A1 (en) * | 2003-12-23 | 2005-07-14 | Alza Corporation | Methods and dosage forms for increasing solubility of drug compositions for controlled delivery |
AU2004312084A1 (en) * | 2003-12-29 | 2005-07-21 | Alza Corporation, Inc. | Novel drug compositions and dosage forms of topiramate |
CA2551815A1 (en) * | 2003-12-29 | 2005-07-21 | Alza Corporation | Novel drug compositions and dosage forms |
US20050175696A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Drug granule coatings that impart smear resistance during mechanical compression |
HUE037643T2 (hu) | 2004-06-12 | 2018-09-28 | Collegium Pharmaceutical Inc | Visszaélésre nem alkalmas gyógyszerkészítmények |
US20050287213A1 (en) * | 2004-06-28 | 2005-12-29 | Wong Patrick S | Dosage forms for low solubility and or low dissolution rate free acid pharmaceutical agents |
US20050287212A1 (en) * | 2004-06-28 | 2005-12-29 | Liang-Chang Dong | Oral delivery system comprising a drug/polymer complex |
US8080560B2 (en) * | 2004-12-17 | 2011-12-20 | 3M Innovative Properties Company | Immune response modifier formulations containing oleic acid and methods |
WO2006069030A1 (en) * | 2004-12-20 | 2006-06-29 | Collegium Pharmaceutical, Inc. | Pharmaceutical compositions for sleep disorders |
JP5002904B2 (ja) * | 2005-04-04 | 2012-08-15 | ブラザー工業株式会社 | 無線タグ通信装置、その通信方法、及びその通信プログラム |
EP2026815B1 (en) * | 2006-04-26 | 2011-01-26 | Supernus Pharmaceuticals, Inc. | Controlled released preparations of oxcarbazepine having sigmoidal release profile |
EP2041214A4 (en) | 2006-07-10 | 2009-07-08 | Medipacs Inc | SUPERELASTIC EPOXY HYDROGEL |
BRPI0811732A2 (pt) * | 2007-06-08 | 2014-11-18 | Boehring Ingelheim Internat Gmbh | Formulação de liberação prolongada de nevirapina |
US8637080B2 (en) * | 2007-06-28 | 2014-01-28 | Osmotica Kereskedelmi és Szolgáltató, KFT | Rupturing controlled release device comprising a subcoat |
US20090036414A1 (en) * | 2007-08-02 | 2009-02-05 | Mutual Pharmaceutical Company, Inc. | Mesalamine Formulations |
EP2227635A2 (en) | 2007-12-03 | 2010-09-15 | Medipacs, Inc. | Fluid metering device |
CA2757979A1 (en) * | 2009-04-09 | 2010-10-14 | Alkermes Pharma Ireland Limited | Controlled-release clozapine compositions |
WO2011032011A1 (en) | 2009-09-10 | 2011-03-17 | Medipacs, Inc. | Low profile actuator and improved method of caregiver controlled administration of therapeutics |
EP2498763A4 (en) | 2009-11-09 | 2015-10-07 | Spotlight Technology Partners Llc | HYDROGELS BASED ON POLYSACCHARIDE |
US8795727B2 (en) | 2009-11-09 | 2014-08-05 | Spotlight Technology Partners Llc | Fragmented hydrogels |
US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US20110172639A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Device and method for delivery of microneedle to desired depth within the skin |
US20110172609A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Microneedle component assembly for drug delivery device |
US20110172637A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Drug delivery device including tissue support structure |
US20110172645A1 (en) * | 2010-01-08 | 2011-07-14 | Ratio, Inc. | Wearable drug delivery device including integrated pumping and activation elements |
WO2011086047A1 (en) | 2010-01-13 | 2011-07-21 | Azur Pharma Limited | Method for titrating clozapine |
US9500186B2 (en) | 2010-02-01 | 2016-11-22 | Medipacs, Inc. | High surface area polymer actuator with gas mitigating components |
US8668675B2 (en) | 2010-11-03 | 2014-03-11 | Flugen, Inc. | Wearable drug delivery device having spring drive and sliding actuation mechanism |
DK2826467T3 (en) | 2010-12-22 | 2017-10-16 | Purdue Pharma Lp | INCLUDED, MANIPULATION-PROPOSED SLOW-DELIVERY DOSAGE FORMS |
CN107412173A (zh) | 2010-12-23 | 2017-12-01 | 普渡制药公司 | 抗篡改固体口服剂型 |
US20130143867A1 (en) | 2011-12-02 | 2013-06-06 | Sychroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
AU2013229274A1 (en) * | 2012-03-05 | 2014-09-04 | Cipla Limited | Pharmaceutical antiretroviral combinations comprising lamivudine, festinavir and nevirapine |
EP2847249A4 (en) | 2012-03-14 | 2016-12-28 | Medipacs Inc | SMART POLYMER MATERIALS WITH EXCESSIVE REACTIVE MOLECULES |
US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
US20140322320A1 (en) * | 2013-04-24 | 2014-10-30 | Uday Saxena | Novel compositions for emesis control in cancer patients undergoing chemotherapy and methods thereof |
CA2914365C (en) | 2013-06-05 | 2022-03-15 | Synchroneuron, Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
US10973783B2 (en) | 2015-12-30 | 2021-04-13 | Adamas Pharmaceuticals, Inc. | Methods and compositions for the treatment of seizure-related disorders |
US9737530B1 (en) | 2016-06-23 | 2017-08-22 | Collegium Pharmaceutical, Inc. | Process of making stable abuse-deterrent oral formulations |
CN112236138B (zh) | 2017-12-05 | 2024-05-31 | 赛诺维信制药公司 | 晶体形式及其制备方法 |
CA3084953A1 (en) | 2017-12-05 | 2019-06-13 | Sunovion Pharmaceuticals Inc. | Nonracemic mixtures and uses thereof |
SG11202113266YA (en) | 2019-06-04 | 2021-12-30 | Sunovion Pharmaceuticals Inc | Modified release formulations and uses thereof |
CN115487161B (zh) * | 2022-11-18 | 2023-03-03 | 山东则正医药技术有限公司 | 一种氨磺必利片的制备方法 |
Family Cites Families (28)
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---|---|---|---|---|
US2799241A (en) | 1949-01-21 | 1957-07-16 | Wisconsin Alumni Res Found | Means for applying coatings to tablets or the like |
US3173876A (en) | 1960-05-27 | 1965-03-16 | John C Zobrist | Cleaning methods and compositions |
NL271831A (es) | 1960-11-29 | |||
US3276586A (en) | 1963-08-30 | 1966-10-04 | Rosaen Filter Co | Indicating means for fluid filters |
NL6714885A (es) | 1967-11-02 | 1969-05-06 | ||
US3541006A (en) | 1968-07-03 | 1970-11-17 | Amicon Corp | Ultrafiltration process |
US3541005A (en) | 1969-02-05 | 1970-11-17 | Amicon Corp | Continuous ultrafiltration of macromolecular solutions |
US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
GB1478759A (en) | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
US4077407A (en) | 1975-11-24 | 1978-03-07 | Alza Corporation | Osmotic devices having composite walls |
US4063064A (en) | 1976-02-23 | 1977-12-13 | Coherent Radiation | Apparatus for tracking moving workpiece by a laser beam |
US4285987A (en) | 1978-10-23 | 1981-08-25 | Alza Corporation | Process for manufacturing device with dispersion zone |
US4200098A (en) | 1978-10-23 | 1980-04-29 | Alza Corporation | Osmotic system with distribution zone for dispensing beneficial agent |
US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4449983A (en) * | 1982-03-22 | 1984-05-22 | Alza Corporation | Simultaneous delivery of two drugs from unit delivery device |
US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
US4863456A (en) | 1986-04-30 | 1989-09-05 | Alza Corporation | Dosage form with improved delivery capability |
US4743248A (en) * | 1986-08-11 | 1988-05-10 | Alza Corporation | Dosage form for delivering acid sensitive beneficial agent |
US4891223A (en) * | 1987-09-03 | 1990-01-02 | Air Products And Chemicals, Inc. | Controlled release delivery coating formulation for bioactive substances |
US4931285A (en) * | 1988-04-28 | 1990-06-05 | Alza Corporation | Aqueous based pharmaceutical coating composition for dosage forms |
US4902514A (en) | 1988-07-21 | 1990-02-20 | Alza Corporation | Dosage form for administering nilvadipine for treating cardiovascular symptoms |
ES2054333T3 (es) * | 1989-01-30 | 1994-08-01 | Alza Corp | Forma de dosificacion para administrar un antagonista del calcio. |
DE69107461T2 (de) * | 1990-08-07 | 1995-06-22 | Pfizer | Verwendung von interfacial polymerisierten membranen in abgabevorrichtungen. |
ATE195252T1 (de) * | 1993-04-23 | 2000-08-15 | Novartis Erfind Verwalt Gmbh | Wirkstoffabgabevorrichtung mit gesteuerter freigabe |
US5674895A (en) * | 1995-05-22 | 1997-10-07 | Alza Corporation | Dosage form comprising oxybutynin |
US5840329A (en) * | 1997-05-15 | 1998-11-24 | Bioadvances Llc | Pulsatile drug delivery system |
-
1998
- 1998-11-23 AU AU15346/99A patent/AU1534699A/en not_active Abandoned
- 1998-11-23 EP EP98959576A patent/EP1035834B1/en not_active Expired - Lifetime
- 1998-11-23 WO PCT/US1998/025027 patent/WO1999029297A1/en active IP Right Grant
- 1998-11-23 DK DK98959576T patent/DK1035834T3/da active
- 1998-11-23 ES ES98959576T patent/ES2172944T3/es not_active Expired - Lifetime
- 1998-11-23 PT PT98959576T patent/PT1035834E/pt unknown
- 1998-11-23 AT AT98959576T patent/ATE216220T1/de not_active IP Right Cessation
- 1998-11-23 DE DE69805001T patent/DE69805001T2/de not_active Expired - Fee Related
- 1998-12-04 US US09/206,211 patent/US6210712B1/en not_active Expired - Lifetime
-
2001
- 2001-03-19 HK HK01101964A patent/HK1031197A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1999029297A1 (en) | 1999-06-17 |
DE69805001D1 (de) | 2002-05-23 |
EP1035834A1 (en) | 2000-09-20 |
HK1031197A1 (en) | 2001-06-08 |
DE69805001T2 (de) | 2002-08-22 |
DK1035834T3 (da) | 2002-07-08 |
ATE216220T1 (de) | 2002-05-15 |
AU1534699A (en) | 1999-06-28 |
US6210712B1 (en) | 2001-04-03 |
EP1035834B1 (en) | 2002-04-17 |
PT1035834E (pt) | 2002-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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