ES2171110A1 - Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion. - Google Patents

Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion.

Info

Publication number
ES2171110A1
ES2171110A1 ES200000522A ES200000522A ES2171110A1 ES 2171110 A1 ES2171110 A1 ES 2171110A1 ES 200000522 A ES200000522 A ES 200000522A ES 200000522 A ES200000522 A ES 200000522A ES 2171110 A1 ES2171110 A1 ES 2171110A1
Authority
ES
Spain
Prior art keywords
ibuprofen
preparation
procedure
pharmaceutical composition
composition based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200000522A
Other languages
English (en)
Other versions
ES2171110B1 (es
Inventor
Perez M Teresa Tarre
Casas Montserrat Trullois
Faus Xavier Font
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio de Aplicaciones Farmacodinamicas SA
Original Assignee
Laboratorio de Aplicaciones Farmacodinamicas SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio de Aplicaciones Farmacodinamicas SA filed Critical Laboratorio de Aplicaciones Farmacodinamicas SA
Priority to ES200000522A priority Critical patent/ES2171110B1/es
Priority to CZ20010714A priority patent/CZ301553B6/cs
Priority to PT01500053T priority patent/PT1129709E/pt
Priority to AT01500053T priority patent/ATE298567T1/de
Priority to EP01500053A priority patent/EP1129709B1/en
Priority to DK01500053T priority patent/DK1129709T3/da
Priority to SK293-2001A priority patent/SK285338B6/sk
Priority to DE60111657T priority patent/DE60111657T2/de
Publication of ES2171110A1 publication Critical patent/ES2171110A1/es
Application granted granted Critical
Publication of ES2171110B1 publication Critical patent/ES2171110B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Rheumatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composición farmacéutica a base de ibuprofeno y procedimiento para su preparación. La composición, en forma de polvo, comprende como componente activo lisinato de ibuprofeno, en combinación con ciclodextrina, y otros excipientes farmacéuticamente adecuados. Su preparación comprende: tamizar por separado la sal ibuprofeno y la ciclodextrina, mezclar estos componentes, someter la mezcla a un mezclado ultrarrápido, y tamizar y mezclar la mezcla resultante junto con los excipientes.
ES200000522A 2000-03-03 2000-03-03 Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion. Expired - Fee Related ES2171110B1 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ES200000522A ES2171110B1 (es) 2000-03-03 2000-03-03 Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion.
CZ20010714A CZ301553B6 (cs) 2000-03-03 2001-02-26 Farmaceutický prípravek na bázi ibuprofenu a zpusob jeho prípravy
AT01500053T ATE298567T1 (de) 2000-03-03 2001-03-01 Pharmazeutische zusammensetzung enthaltend ibuprofen und ein verfahren zur deren herstellung
EP01500053A EP1129709B1 (en) 2000-03-03 2001-03-01 Pharmaceutical composition based on ibuprofen and a procedure for the preparation thereof
PT01500053T PT1129709E (pt) 2000-03-03 2001-03-01 Composicao farmaceutica a base de ibuprofeno e um procedimento para a sua preparacao
DK01500053T DK1129709T3 (da) 2000-03-03 2001-03-01 Farmaceutisk sammensætning indeholdende ibuprofen og fremgangsmåde til fremstilling heraf
SK293-2001A SK285338B6 (sk) 2000-03-03 2001-03-01 Farmaceutický prípravok na báze ibuprofénu a spôsob jeho prípravy
DE60111657T DE60111657T2 (de) 2000-03-03 2001-03-01 Pharmazeutische Zusammensetzung enthaltend Ibuprofen und ein Verfahren zur deren Herstellung

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200000522A ES2171110B1 (es) 2000-03-03 2000-03-03 Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion.

Publications (2)

Publication Number Publication Date
ES2171110A1 true ES2171110A1 (es) 2002-08-16
ES2171110B1 ES2171110B1 (es) 2003-06-16

Family

ID=8492565

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200000522A Expired - Fee Related ES2171110B1 (es) 2000-03-03 2000-03-03 Composicion farmaceutica a base de ibuprofeno y procedimiento para su preparacion.

Country Status (8)

Country Link
EP (1) EP1129709B1 (es)
AT (1) ATE298567T1 (es)
CZ (1) CZ301553B6 (es)
DE (1) DE60111657T2 (es)
DK (1) DK1129709T3 (es)
ES (1) ES2171110B1 (es)
PT (1) PT1129709E (es)
SK (1) SK285338B6 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0028575D0 (en) * 2000-11-23 2001-01-10 Elan Corp Plc Oral pharmaceutical compositions containing cyclodextrins
KR20080034166A (ko) * 2005-11-02 2008-04-18 테이코쿠 팔마 유에스에이, 인코포레이티드 감각기관 수용성 이부프로펜 경구 투약 제형 및 동일물의제조 및 사용 방법
EP1840188B1 (en) 2006-03-31 2011-09-07 Sony Deutschland GmbH A composition comprising at least one type of liquid crystal
ES2303468B1 (es) * 2007-01-22 2009-06-08 Masterfarm, S.L "una composicion farmaceutica pulverulenta que comprende ibuprofeno".
EP1974751A1 (en) * 2007-03-26 2008-10-01 The Jordanian Pharmaceutical Manufacturing Co. Formulations for non-steroidal anti-inflammatory drugs
FR2914187B1 (fr) * 2007-03-28 2011-01-21 Pf Medicament Complexes d'ibuprofene, de cyclodextrines et d'agents ternaires, et leurs utilisations en pharmaceutique.
US20120101159A1 (en) * 2009-04-27 2012-04-26 Laboratorio De Aplicaciones Farmacodinamicas, S.A. Ibuprofen lysinate oral suspension
DK2253329T3 (en) 2009-04-27 2017-01-16 Laboratorio De Aplicaciones Farm S A Oral ibuprofen lysinate suspension.
WO2014194872A1 (en) 2013-06-04 2014-12-11 Zentiva, K.S. Taste masking of water soluble drugs using poloxamers

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000725A1 (en) * 1990-07-13 1992-01-23 Farcon Ag Liquid oral pharmaceutical compositions having anti-inflammatory activity
ES2052914T3 (es) * 1988-06-09 1994-07-16 Reckitt & Colmann Prod Ltd Un procedimiento para preparar un complejo de beta-dextrina con una sal de ibuprofeno.
WO1995004528A2 (en) * 1993-08-10 1995-02-16 Smithkline Beecham Plc PHARMACEUTICAL COMPOSITION CONTAINING A DRUG/β-CYCLODEXTRIN COMPLEX IN COMBINATION WITH AN ACID-BASE COUPLE
WO1996014839A1 (en) * 1994-11-15 1996-05-23 Farmarc Nederland Bv Pharmaceutical composition comprising non-steroidal anti-inflammatory drugs
US5597583A (en) * 1992-04-10 1997-01-28 Smithkline Beecham P.L.C. Pharmaceutical composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038314A1 (de) * 1990-11-30 1992-06-04 Puetter Medice Chem Pharm Komplexe des aktiven enantiomers des ibuprofens mit cyclodextrin

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052914T3 (es) * 1988-06-09 1994-07-16 Reckitt & Colmann Prod Ltd Un procedimiento para preparar un complejo de beta-dextrina con una sal de ibuprofeno.
WO1992000725A1 (en) * 1990-07-13 1992-01-23 Farcon Ag Liquid oral pharmaceutical compositions having anti-inflammatory activity
US5597583A (en) * 1992-04-10 1997-01-28 Smithkline Beecham P.L.C. Pharmaceutical composition
WO1995004528A2 (en) * 1993-08-10 1995-02-16 Smithkline Beecham Plc PHARMACEUTICAL COMPOSITION CONTAINING A DRUG/β-CYCLODEXTRIN COMPLEX IN COMBINATION WITH AN ACID-BASE COUPLE
WO1996014839A1 (en) * 1994-11-15 1996-05-23 Farmarc Nederland Bv Pharmaceutical composition comprising non-steroidal anti-inflammatory drugs

Also Published As

Publication number Publication date
EP1129709A2 (en) 2001-09-05
CZ2001714A3 (cs) 2001-10-17
DE60111657D1 (de) 2005-08-04
DE60111657T2 (de) 2006-05-04
ATE298567T1 (de) 2005-07-15
CZ301553B6 (cs) 2010-04-14
PT1129709E (pt) 2005-10-31
SK2932001A3 (en) 2001-12-03
EP1129709A3 (en) 2001-11-14
ES2171110B1 (es) 2003-06-16
EP1129709B1 (en) 2005-06-29
DK1129709T3 (da) 2005-10-24
SK285338B6 (sk) 2006-11-03

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