ES2170245T3 - Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos. - Google Patents
Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos.Info
- Publication number
- ES2170245T3 ES2170245T3 ES96922890T ES96922890T ES2170245T3 ES 2170245 T3 ES2170245 T3 ES 2170245T3 ES 96922890 T ES96922890 T ES 96922890T ES 96922890 T ES96922890 T ES 96922890T ES 2170245 T3 ES2170245 T3 ES 2170245T3
- Authority
- ES
- Spain
- Prior art keywords
- matrix
- layers
- contact surfaces
- controlled release
- prefabricated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000013270 controlled release Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000010410 layer Substances 0.000 abstract 7
- 239000011159 matrix material Substances 0.000 abstract 6
- 239000013543 active substance Substances 0.000 abstract 3
- 239000011247 coating layer Substances 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Electrotherapy Devices (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
Abstract
LA INVENCION TRATA DE UNA TABLETA RECUBIERTA PARA LA LIBERACION CONTROLADA DE SUSTANCIAS ACTIVAS EN UN MEDIO LIQUIDO CON AL MENOS UNA MATRIZ EN CAPAS, QUE CONTIENE SUSTANCIAS ACTIVAS Y QUE MUESTRA UNAS SUPERFICIES DE CONTACTO PARA CONTACTAR CON EL MEDIO LIQUIDO. LAS SUPERFICIES DE CONTACTO DE LA MATRIZ CONTIENEN, EN PARTE, UNA CAPA DE RECUBRIMIENTO QUE RETARDA O IMPIDE LA LIBERACION DE LAS SUSTANCIAS ACTIVAS. LA INVENCION ESTA CARACTERIZADA PORQUE LA CAPA DE RECUBRIMIENTO ES UNA CAPA ADICIONAL APLICADA A LAS SUPERFICIES DE CONTACTO DE LA MATRIZ PREFABRICADA EN CAPAS O LA MATRIZ ES AL MENOS UNA CAPA ADICIONAL QUE CONTACTA CON LAS SUPERFICIES DE CONTACTO DE LA MATRIZ PREFABRICADA EN CAPAS; LA CAPA ADICIONAL SE APLICA PRENSANDO MATERIAL GRANULADO O PULVERULENTO SOBRE LA MATRIZ PREFABRICADA EN CAPAS CON UN ESPESOR EN GRADIENTE O LA CAPA DE RECUBRIMIENTO PREFABRICADA EN CAPAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19524753A DE19524753A1 (de) | 1995-07-07 | 1995-07-07 | Schichttablette zur kontrollierten Freisetzung von Wirkstoffen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2170245T3 true ES2170245T3 (es) | 2002-08-01 |
Family
ID=7766243
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96922890T Expired - Lifetime ES2170245T3 (es) | 1995-07-07 | 1996-06-24 | Metodo para la fabricacion de comprimidos estratificados para la liberacion controlada de principios activos. |
Country Status (20)
Country | Link |
---|---|
US (1) | US6083533A (es) |
EP (1) | EP0837674B1 (es) |
JP (1) | JPH11510484A (es) |
KR (1) | KR100404121B1 (es) |
CN (1) | CN1190343A (es) |
AT (1) | ATE210972T1 (es) |
AU (1) | AU710828B2 (es) |
CZ (1) | CZ420997A3 (es) |
DE (2) | DE19524753A1 (es) |
DK (1) | DK0837674T3 (es) |
ES (1) | ES2170245T3 (es) |
HU (1) | HUP9901715A3 (es) |
MY (1) | MY113919A (es) |
NO (1) | NO976140D0 (es) |
NZ (1) | NZ312136A (es) |
PL (1) | PL324487A1 (es) |
PT (1) | PT837674E (es) |
SK (1) | SK1498A3 (es) |
WO (1) | WO1997002812A2 (es) |
ZA (1) | ZA965710B (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6555139B2 (en) | 1999-06-28 | 2003-04-29 | Wockhardt Europe Limited | Preparation of micron-size pharmaceutical particles by microfluidization |
HRP20020124A2 (en) * | 2002-02-11 | 2003-10-31 | Pliva D D | Sustained/controlled release solid formulation as a novel drug delivery system with reduced risk of dose dumping |
US7309444B2 (en) * | 2002-08-29 | 2007-12-18 | Stellar Technology Company | Layered tablet water treatment compositions and method of use |
US6852238B2 (en) * | 2002-08-29 | 2005-02-08 | Steller Technology Company | Layered tablet water treatment compositions and method of use |
US20060251722A1 (en) * | 2005-05-03 | 2006-11-09 | Novavax, Inc. | Multi-component vitamin and mineral supplement for the optimal absorption of components |
US20080286343A1 (en) * | 2007-05-16 | 2008-11-20 | Dzenana Cengic | Solid form |
EP2379226B1 (en) | 2008-12-31 | 2016-04-20 | 3M Innovative Properties Company | Live bioload detection using microparticles |
EP2379697A2 (en) | 2008-12-31 | 2011-10-26 | 3M Innovative Properties Company | Sampling devices and methods for concentrating microorganisms |
WO2010129726A1 (en) * | 2009-05-06 | 2010-11-11 | 3M Innovative Properties Company | Articles with matrix comprising a cell extractant and biodetection methods thereof |
BR112012016119B1 (pt) | 2009-12-30 | 2020-04-28 | 3M Innovative Properties Co | método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit |
US8845801B2 (en) | 2009-12-30 | 2014-09-30 | Regents Of The University Of Minnesota | Bone cement and method |
CN110538158A (zh) * | 2019-09-10 | 2019-12-06 | 郑州百瑞动物药业有限公司 | 一种水产用长效缓释双层片状消毒剂及其制备方法 |
CN113768038A (zh) * | 2021-09-14 | 2021-12-10 | 江苏省协同医药生物工程有限责任公司 | 一种精准定量实验动物功能性饲料及制备方法与设备 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1248571A (en) * | 1917-04-30 | 1917-12-04 | Francis J Stokes | Machine for applying and compressing powder on tablets. |
DE3221425A1 (de) * | 1982-06-07 | 1983-12-08 | Boehringer Ingelheim KG, 6507 Ingelheim | Hydrolyseempfindlichen wirkstoff enthaltende, lagerstabile tablette |
DE3814532A1 (de) * | 1988-04-29 | 1989-11-09 | Bayer Ag | Dhp-retard-zubereitung |
DE4100920A1 (de) * | 1991-01-15 | 1992-07-16 | Degussa | Wirkstoffzubereitung zur oralen verabreichung an wiederkaeuer |
IT1256393B (it) * | 1992-11-17 | 1995-12-04 | Inverni Della Beffa Spa | Forme matriciali multistrato per il rilascio controllato di principi attivi |
DE4341442C2 (de) * | 1993-12-04 | 1998-11-05 | Lohmann Therapie Syst Lts | Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung |
DE4416926C2 (de) * | 1994-05-13 | 2000-01-13 | Lohmann Therapie Syst Lts | Verfahren zur Herstellung von Vorrichtungen zur kontrollierten Freisetzung von Wirkstoffen |
-
1995
- 1995-07-07 DE DE19524753A patent/DE19524753A1/de not_active Withdrawn
-
1996
- 1996-06-24 NZ NZ312136A patent/NZ312136A/xx unknown
- 1996-06-24 PT PT96922890T patent/PT837674E/pt unknown
- 1996-06-24 EP EP96922890A patent/EP0837674B1/de not_active Expired - Lifetime
- 1996-06-24 HU HU9901715A patent/HUP9901715A3/hu unknown
- 1996-06-24 AU AU63598/96A patent/AU710828B2/en not_active Ceased
- 1996-06-24 PL PL96324487A patent/PL324487A1/xx unknown
- 1996-06-24 CN CN96195323A patent/CN1190343A/zh active Pending
- 1996-06-24 DK DK96922890T patent/DK0837674T3/da active
- 1996-06-24 SK SK14-98A patent/SK1498A3/sk unknown
- 1996-06-24 US US08/983,278 patent/US6083533A/en not_active Expired - Fee Related
- 1996-06-24 KR KR10-1998-0700083A patent/KR100404121B1/ko not_active IP Right Cessation
- 1996-06-24 DE DE59608511T patent/DE59608511D1/de not_active Expired - Fee Related
- 1996-06-24 ES ES96922890T patent/ES2170245T3/es not_active Expired - Lifetime
- 1996-06-24 WO PCT/EP1996/002736 patent/WO1997002812A2/de active IP Right Grant
- 1996-06-24 JP JP9505453A patent/JPH11510484A/ja active Pending
- 1996-06-24 CZ CZ974209A patent/CZ420997A3/cs unknown
- 1996-06-24 AT AT96922890T patent/ATE210972T1/de not_active IP Right Cessation
- 1996-06-28 MY MYPI96002655A patent/MY113919A/en unknown
- 1996-07-05 ZA ZA965710A patent/ZA965710B/xx unknown
-
1997
- 1997-12-30 NO NO976140A patent/NO976140D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US6083533A (en) | 2000-07-04 |
EP0837674B1 (de) | 2001-12-19 |
AU6359896A (en) | 1997-02-10 |
WO1997002812A2 (de) | 1997-01-30 |
MX9800244A (es) | 1998-07-31 |
DE19524753A1 (de) | 1997-01-23 |
PL324487A1 (en) | 1998-05-25 |
AU710828B2 (en) | 1999-09-30 |
HUP9901715A2 (hu) | 1999-10-28 |
NO976140L (no) | 1997-12-30 |
HUP9901715A3 (en) | 2001-04-28 |
CN1190343A (zh) | 1998-08-12 |
SK1498A3 (en) | 1998-09-09 |
ATE210972T1 (de) | 2002-01-15 |
DE59608511D1 (de) | 2002-01-31 |
DK0837674T3 (da) | 2002-04-08 |
EP0837674A2 (de) | 1998-04-29 |
NZ312136A (en) | 1999-02-25 |
WO1997002812A3 (de) | 1997-03-27 |
ZA965710B (en) | 1997-01-24 |
KR100404121B1 (ko) | 2004-02-11 |
KR19990028783A (ko) | 1999-04-15 |
MY113919A (en) | 2002-06-29 |
CZ420997A3 (cs) | 1998-06-17 |
NO976140D0 (no) | 1997-12-30 |
JPH11510484A (ja) | 1999-09-14 |
PT837674E (pt) | 2002-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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