ES2167661T3 - Transformacion de xantofilas. - Google Patents

Transformacion de xantofilas.

Info

Publication number
ES2167661T3
ES2167661T3 ES97116944T ES97116944T ES2167661T3 ES 2167661 T3 ES2167661 T3 ES 2167661T3 ES 97116944 T ES97116944 T ES 97116944T ES 97116944 T ES97116944 T ES 97116944T ES 2167661 T3 ES2167661 T3 ES 2167661T3
Authority
ES
Spain
Prior art keywords
luteine
zeaxantine
teguments
organization
transformation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97116944T
Other languages
English (en)
Inventor
Kurt Bernhard
Alfred Giger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of ES2167661T3 publication Critical patent/ES2167661T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Fodder In General (AREA)

Abstract

UN PROCEDIMIENTO PARA LA TRANSFORMACION DE LUTEINA O DE LOS ESTERES DE LA MISMA EXISTENTES EN LA NATURALEZA EN ZEAXANTINA MEDIANTE ISOMERIZACION CATALIZADA CON BASES CONSISTE, EN QUE OPCIONALMENTE UN PRODUCTO QUE CONTIENE LUTEINA QUE EXISTE DE FORMA NATURAL O LUTEINA PURA SE CALIENTA EN UNA MEZCLA DE UNA SOLUCION ACUOSA DE UN HIDROXIDO ALCALINO Y O DIMETILSULFOXIDO O UN DISOLVENTE ORGANICO BASADO EN UN HIDROCARBURO ALIFATICO SATURADO Y/O AROMATICO A UNA TEMPERATURA SUPERIOR A APROXIMADAMENTE 50 (GRADOS) C, DONDE EN EL CASO DEL USO DEL DISOLVENTE ORGANICO BASADO EN UN HIDROCARBURO, EL PROCEDIMIENTO SE REALIZA EN PRESENCIA DE UN CATALIZADOR DE TRANSFERENCIA DE FASE. COMO CAROTENOIDES LA LUTEINA Y LA ZEAXANTINA SE UTILIZAN ESPECIALMENTE PARA PIGMENTOS DE LA YEMA DE HUEVO, TEGUMENTOS Y LA GRASA SUBCUTANEA DE LAS AVES, LA CARNE Y LOS TEGUMENTOS DE PECES Y CRUSTACEOS, ASI COMO ALIMENTOS. PARA MUCHOS USOS SE UTILIZA PREFERENTEMENTE LA ZEAXANTINA, YA QUE ESTA EN UNA DOSIFICACION COMPARABLE DA LUGARA UNA PIGMENTACION AMARILLA DORADA MAS INTENSA QUE LA LUTEINA.
ES97116944T 1996-10-04 1997-09-30 Transformacion de xantofilas. Expired - Lifetime ES2167661T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96115908 1996-10-04

Publications (1)

Publication Number Publication Date
ES2167661T3 true ES2167661T3 (es) 2002-05-16

Family

ID=8223265

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97116944T Expired - Lifetime ES2167661T3 (es) 1996-10-04 1997-09-30 Transformacion de xantofilas.

Country Status (8)

Country Link
US (1) US5780693A (es)
JP (1) JP3828252B2 (es)
CN (1) CN1082507C (es)
AT (1) ATE210166T1 (es)
BR (1) BR9704976A (es)
DE (1) DE59705649D1 (es)
ES (1) ES2167661T3 (es)
ID (1) ID19677A (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827652A (en) 1995-10-31 1998-10-27 Applied Food Biotechnology, Inc. Zeaxanthin formulations for human ingestion
US5998678A (en) * 1997-02-25 1999-12-07 Investigaciones Quimicas Y Farmaceutics, S.A. Process for preparing carotenoid pigments
AU752468B2 (en) 1997-04-04 2002-09-19 Phyllis E. Bowen Lutein esters having high bioavailability
US5876782A (en) * 1997-05-14 1999-03-02 Kemin Industries, Inc. Method for the conversion of xanthophylls in plant material
IN189750B (es) * 1997-10-31 2003-04-19 Bioquimex Reka S A De C V
US6573299B1 (en) 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
US6504067B1 (en) * 1999-11-24 2003-01-07 Industrial Organica S.A. De C.V. Process to obtain xanthophyll concentrates of high purity
US6818798B1 (en) 2000-05-03 2004-11-16 University Of Maryland, College Park Process for making a (3R,3′R)-zeaxanthin precursor
US6420614B1 (en) * 2000-10-10 2002-07-16 Industrial Organica, S.A. De C.V. Process for obtaining 3′-epilutein
US7691406B2 (en) * 2000-10-27 2010-04-06 ZeaVision LLC. Zeaxanthin formulations for human ingestion
US6784351B2 (en) * 2001-06-29 2004-08-31 Ball Horticultural Company Targetes erecta marigolds with altered carotenoid compositions and ratios
US7173145B2 (en) * 2001-11-29 2007-02-06 University Of Maryland, College Park Process for extraction and purification of lutein, zeaxanthin and rare carotenoids from marigold flowers and plants
US8088363B2 (en) 2002-10-28 2012-01-03 Zeavision Llc Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin
US9192586B2 (en) 2003-03-10 2015-11-24 Zeavision Llc Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders
US20070082066A1 (en) * 2003-05-07 2007-04-12 Gierhart Dennis L Use of zeaxanthin to reduce light hyper-sensitivity, photophobia, and medical conditions relating to light hyper-sensitivity
DE10349455A1 (de) * 2003-10-23 2005-05-25 Bioghurt Biogarde Gmbh & Co. Kg Verfahren zur Herstellung konjugierter, mehrfach ungesättigter Fettsäureester
US7941211B2 (en) * 2003-11-17 2011-05-10 Zeavision, Llc. Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders
US7351424B2 (en) * 2004-07-22 2008-04-01 Bio Lut S.A. De C.V. Enhanced purity trans-lutein-ester compositions and methods of making same
US20060089411A1 (en) * 2004-08-07 2006-04-27 Gierhart Dennis L Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin
US20070065487A1 (en) * 2005-09-21 2007-03-22 Bio Lut S.A. De C.V. Trans-lutein xantophyll ester of high purity and high bioavailability in micellar solution and a process for the preparation thereof
AT503329A1 (de) * 2006-03-02 2007-09-15 Omnica Gmbh Verfahren zur herstellung einer zusammensetzung, welche zumindest ein xantophyll enthält
US8212063B2 (en) * 2006-05-10 2012-07-03 Omniactive Health Technologies Limited Xanthophyll composition containing trans, meso-zeaxanthin, trans, R, R-zeaxanthin and trans, R, R-lutein useful for nutrition and health care and a process for its preparation
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
CN101153017B (zh) * 2006-09-28 2010-12-22 浙江医药股份有限公司新昌制药厂 高含量食用级玉米黄质的制备方法
WO2009019712A1 (en) * 2007-08-03 2009-02-12 Omniactive Health Technologies Pvt Ltd. Novel xanthophyll composition contaning (trans, meso) - zeaxanthin, and a process for its preparation
US8093436B2 (en) * 2008-03-19 2012-01-10 University Of Maryland, College Park Process for synthesis of (3R,3′R)-zeaxanthin and (3R,3′S;meso)-zeaxanthin from (3R,3′R,6′R)-lutein via (3R)-3′,4′-anhydrolutein
PT2473065E (pt) 2009-09-02 2016-06-03 Omniactive Health Tech Ltd Uma composição de xantofila contendo pigmentos maculares e um processo para a sua preparação
CN101781240B (zh) * 2010-01-07 2014-06-04 浙江医药股份有限公司新昌制药厂 一种以植物油树脂为原料制备含较高玉米黄质含量的叶黄素晶体的方法
JP2014529607A (ja) 2011-08-26 2014-11-13 ピーティーティー グローバル ケミカル パブリック カンパニー リミテッド 天然物質からルテイン／キサントフィルを抽出する方法、並びにこの方法により得られる高度精製ルテイン／キサントフィル
CN102399178A (zh) * 2011-10-29 2012-04-04 南昌大学 一种由叶黄素酯一锅法转化为玉米黄素的方法
CN102746203B (zh) * 2012-07-12 2014-08-27 浙江医药股份有限公司新昌制药厂 一种高含量玉米黄素的制备方法
CN102757373B (zh) * 2012-07-31 2014-03-19 沈阳天峰生物制药有限公司 一种由万寿菊花粒制备高纯度叶黄素酯的方法
CN105399653B (zh) * 2014-08-27 2017-10-10 浙江医药股份有限公司新昌制药厂 一种由万寿菊油树脂一步法制备玉米黄素的工业化方法
CN104447469B (zh) * 2014-12-08 2016-08-17 晨光生物科技集团股份有限公司 叶黄素浸膏高效制备玉米黄质的方法
CN106316908B (zh) * 2015-06-30 2018-02-13 上虞新和成生物化工有限公司 一种高纯度虾青素的合成方法
CN105085351A (zh) * 2015-09-22 2015-11-25 哈尔滨宝德生物技术股份有限公司 叶黄素转化玉米黄质的工艺
CN106977439B (zh) * 2017-03-23 2018-10-02 广州智特奇生物科技股份有限公司 一种叶黄素的异构化方法
CN111548294A (zh) * 2020-04-10 2020-08-18 天津大学 一种叶黄素甲醇溶剂化物晶体及其制备方法
CN114957072A (zh) * 2021-02-25 2022-08-30 内蒙古昶辉生物科技股份有限公司 由万寿菊油膏制备玉米黄质以及玉米黄质微丸的方法
CN114369050B (zh) * 2022-01-21 2023-08-25 山东天音生物科技有限公司 一种叶黄素酯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1046658A (en) * 1964-03-19 1966-10-26 Kodak Ltd Improvements in pigmenting activity of xanthophyll
US3523138A (en) * 1965-03-01 1970-08-04 Eastman Kodak Co Treatment of marigold petal meal to obtain a xanthophyll product
NL6610613A (es) * 1966-07-28 1968-01-29
US3783099A (en) * 1971-11-08 1974-01-01 Ralston Purina Co Xanthophyllic extraction process
JPH0848895A (ja) * 1994-03-28 1996-02-20 Leonardo Espinosa Sanchez Roberto センパスチルの花の粉末、オレオレジン、又は同花から作られた他の形態の物に含まれる人および動物用の色素鹸化及び獲得における改良
US5523494A (en) * 1994-07-20 1996-06-04 Industrial Organica, S.A. De C.V. Process for the isomerization of lutein
ES2107391B1 (es) * 1996-02-27 1998-06-16 Invest Quimicas Y Farmaceutica Procedimiento para la preparacion de carotenoides y pigmentos que los contienen.

Also Published As

Publication number Publication date
ATE210166T1 (de) 2001-12-15
CN1178787A (zh) 1998-04-15
CN1082507C (zh) 2002-04-10
BR9704976A (pt) 1999-07-20
DE59705649D1 (de) 2002-01-17
JP3828252B2 (ja) 2006-10-04
JPH10114739A (ja) 1998-05-06
US5780693A (en) 1998-07-14
ID19677A (id) 1998-07-30

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