ES2167634T3 - Procedimiento y dispositivo para la aglomeracion de sustancias sensibles a la hidrolisis mediante vapor de agua. - Google Patents
Procedimiento y dispositivo para la aglomeracion de sustancias sensibles a la hidrolisis mediante vapor de agua.Info
- Publication number
- ES2167634T3 ES2167634T3 ES97105180T ES97105180T ES2167634T3 ES 2167634 T3 ES2167634 T3 ES 2167634T3 ES 97105180 T ES97105180 T ES 97105180T ES 97105180 T ES97105180 T ES 97105180T ES 2167634 T3 ES2167634 T3 ES 2167634T3
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- vapor
- water vapor
- fall
- aglomeration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/02—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops
- B01J2/04—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by dividing the liquid material into drops, e.g. by spraying, and solidifying the drops in a gaseous medium
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/16—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by suspending the powder material in a gas, e.g. in fluidised beds or as a falling curtain
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Drying Of Solid Materials (AREA)
- Jellies, Jams, And Syrups (AREA)
- Fertilizers (AREA)
- Processing Of Solid Wastes (AREA)
- Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Dairy Products (AREA)
- General Preparation And Processing Of Foods (AREA)
- Glanulating (AREA)
Abstract
EN EL PROCEDIMIENTO PARA LA AGLOMERACION DE SUSTANCIAS DIFICILMENTE SOLUBLES Y SENSIBLES A LA HIDROLISIS SE HACE PASAR EL POLVO DE LA SUSTANCIA DIFICILMENTE SOLUBLE JUNTO CON AL MENOS UN AGLUTINANTE HIDROSOLUBLE EN CAIDA LIBRE POR UNA ATMOSFERA DE VAPOR DE AGUA A UNA TEMPERATURA DE ENTRE 85 (GRADOS) C Y 105 (GRADOS) C BASICAMENTE SIN INFLUENCIA DE FUERZAS COMPACTADORAS. EL TIEMPO DE PERMANENCIA EN LA ATMOSFERA DE VAPOR DE AGUA ES DE ENTRE 0,5 Y 10 SEGUNDOS APROXIMADAMENTE. A CONTINUACION, LOS AGLOMERADOS FORMADOS SE SECAN EN CAIDA LIBRE, DE TAL MANERA QUE EN LOS PUNTOS DE CONTACTO ENTRE LAS PARTICULAS PRIMARIAS PROCEDENTES DE LOS PUENTES DE LIQUIDO-AGLUTINANTE FORMADOS SE FORMAN UNOS PEQUEÑOS PUENTES DE SOLIDO. EN UN SECADOR DE LECHO FLUIDIZADO INTEGRADO A CONTINUACION TIENE LUGAR EL SECADO FINAL HASTA QUE EL CONTENIDO DE AGUA SEA INFERIOR A UN 0,5 % EN PESO. EL PROCEDIMIENTO SE REALIZA EN UN AGLOMERADOR DE CHORRO DE VAPOR EN EL QUE UN VELO DE PRODUCTO QUE CAE LIBREMENTE PROCEDENTE DE LA MEZCLA PULVERULENTA A AGLOMERAR ES CARGADO CON VAPOR DE AGUA PROCEDENTE DE UNOS INYECTORES DE CHORRO DE VAPOR (5,6). EN LA PARTE INFERIOR DEL AGLOMERADOR (1) HAY CONECTADO UN SECADOR DE LECHO FLUIDIZADO (2) DE MANERA QUE LAS PARTICULAS AGLOMERADAS (4) CAEN DIRECTAMENTE EN EL LECHO FLUIDIZADO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19614063 | 1996-04-09 | ||
DE1996123410 DE19623410A1 (de) | 1996-06-12 | 1996-06-12 | Verfahren und Vorrichtung zur Agglomeration von hydrolyseempfindlichen Stoffen mittels Wasserdampf |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2167634T3 true ES2167634T3 (es) | 2002-05-16 |
Family
ID=26024604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97105180T Expired - Lifetime ES2167634T3 (es) | 1996-04-09 | 1997-03-27 | Procedimiento y dispositivo para la aglomeracion de sustancias sensibles a la hidrolisis mediante vapor de agua. |
Country Status (16)
Country | Link |
---|---|
US (2) | US5917081A (es) |
EP (1) | EP0800860B1 (es) |
JP (1) | JPH1033973A (es) |
CN (1) | CN1087185C (es) |
AR (1) | AR006566A1 (es) |
AU (1) | AU723590B2 (es) |
BR (1) | BR9701721A (es) |
CA (1) | CA2201808A1 (es) |
CO (1) | CO4520308A1 (es) |
DE (1) | DE59705322D1 (es) |
ES (1) | ES2167634T3 (es) |
HU (1) | HUP9700725A1 (es) |
MX (1) | MX9702466A (es) |
PL (1) | PL319399A1 (es) |
RU (1) | RU2191065C2 (es) |
TR (1) | TR199700281A2 (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6296868B1 (en) * | 1998-11-19 | 2001-10-02 | Advanced Technology Pharmaceuticals Corporation | Chewable tablets containing mannitol and aspartame |
ATE266997T1 (de) | 1999-08-10 | 2004-06-15 | Aboca S P A | Verfahren zum herstellen von kapseln und tabletten aus naturstoffen pflanzlichen ursprungs |
WO2001080831A2 (en) | 2000-04-27 | 2001-11-01 | Verion Inc. | Zero order release and temperature-controlled microcapsules and process for the preparation thereof |
US6461672B1 (en) * | 2000-08-16 | 2002-10-08 | Genencor International, Inc. | Symmetrical fluidization coater for high capacity manufacturing |
CA2423484A1 (en) | 2000-09-27 | 2002-04-04 | Verion Inc. | Instant water dissolvable encapsulate and process |
NL1020469C2 (nl) * | 2002-04-25 | 2003-10-28 | Carlisle Process Systems B V | Sproeidrooginrichting en toevoermiddel voor een dergelijke sproeidrooginrichting. |
DE10300046B3 (de) * | 2003-01-03 | 2004-05-06 | Universität Karlsruhe (Th) | Verfahren zur Befeuchtung von Pulvern oder Granulaten sowie Vorrichtung hierfür |
AT412473B (de) * | 2003-01-15 | 2005-03-25 | Dsm Fine Chem Austria Gmbh | Verfahren zur kontinuierlichen trocknung von n- bzw. amino-, ammonium- oder spirobicyclische ammoniumgruppen haltigen polymeren |
US7198653B2 (en) * | 2003-07-31 | 2007-04-03 | Delavau Llc | Calcium carbonate granulation |
JP4589251B2 (ja) * | 2006-02-27 | 2010-12-01 | 三栄源エフ・エフ・アイ株式会社 | 粉末の造粒方法及び易溶性顆粒組成物 |
US8708065B2 (en) * | 2009-06-03 | 2014-04-29 | National Oilwell Varco, L.P. | Vessel to condition dry drill cuttings |
RU2449777C1 (ru) * | 2010-12-20 | 2012-05-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ) | Способ получения высокодисперсного парацетамола |
CA2937895C (en) * | 2014-01-25 | 2022-01-11 | Pioneer Pet Products, Llc | Quenched granular absorbent and system and method for making quenched granular absorbent |
EP3117720B1 (de) * | 2015-05-29 | 2019-02-20 | Symrise AG | Grosse agglomeratpartikel |
CN105728223A (zh) * | 2016-03-14 | 2016-07-06 | 刘旭玲 | 一种蒸汽管道熏烟壳 |
PL238977B1 (pl) * | 2017-09-25 | 2021-10-25 | Zakl Produkcyjny Bempresa Spolka Z Ograniczona Odpowiedzialnoscia | Urządzenie do granulowania substancji suchych |
MX2023013049A (es) * | 2021-05-07 | 2023-11-15 | Nestle Sa | Sistema de aglomeracion continua con liquido aglutinante. |
MX2023013063A (es) * | 2021-05-07 | 2023-11-15 | Nestle Sa | Metodo de aglomeracion continua con liquido aglutinante. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2062603A (en) * | 1934-03-26 | 1936-12-01 | Rca Corp | Tuning indicator |
US3143428A (en) * | 1962-10-10 | 1964-08-04 | American Sugar | Method and apparatus for agglomeration |
DE1792752A1 (de) * | 1967-11-21 | 1975-02-06 | Orth Gmbh H | Verfahren zum fortlaufendem herstellen von agglomeraten |
DE1940915C3 (de) * | 1969-08-12 | 1975-06-05 | Meiji Seika Kaisha Ltd., Tokio | Verfahren zur Herstellung von schnell löslichen und dispergierbaren Granulaten aus einem Pulver |
DE2125155B2 (de) * | 1971-05-21 | 1979-10-04 | Babcock-Bsh Ag Vormals Buettner- Schilde-Haas Ag, 4150 Krefeld | Granulieranlage |
GB2130504B (en) * | 1982-09-24 | 1985-11-13 | Freunt Ind Co Ltd | Granulating and coating machine |
EP0163836B1 (de) * | 1984-04-07 | 1988-10-12 | Bayer Ag | Verfahren und Vorrichtung zur Herstellung von Granulaten |
FR2581564B1 (fr) * | 1985-05-13 | 1993-05-07 | Bp Chimie Sa | Appareil a lit fluidise comportant une grille de fluidisation a plusieurs pentes |
WO1993016165A1 (de) * | 1992-02-12 | 1993-08-19 | Henkel Kommanditgesellschaft Auf Aktien | Staubarme aniontensidkonzentrate in pulver- beziehungsweise granulatform mit verbessertem auflösevermögen |
DE4234376A1 (de) * | 1992-10-12 | 1994-04-14 | Henkel Kgaa | Wertstoffe und Wertstoffgemische für Netz-, Wasch- und/oder Reinigungsmittel in neuer Zubereitungsform |
DE4340015C2 (de) * | 1993-11-24 | 1996-07-04 | Henkel Kgaa | Verfahren zur Herstellung wasserfreier, rieselfähiger Zuckertensidpulver und deren Verwendung |
EP0787437A3 (en) * | 1996-02-07 | 1999-01-13 | Societe Des Produits Nestle S.A. | Granular food product |
-
1997
- 1997-03-27 EP EP97105180A patent/EP0800860B1/de not_active Expired - Lifetime
- 1997-03-27 ES ES97105180T patent/ES2167634T3/es not_active Expired - Lifetime
- 1997-03-27 DE DE59705322T patent/DE59705322D1/de not_active Expired - Fee Related
- 1997-04-03 AU AU17717/97A patent/AU723590B2/en not_active Ceased
- 1997-04-03 US US08/832,894 patent/US5917081A/en not_active Expired - Fee Related
- 1997-04-04 MX MX9702466A patent/MX9702466A/es not_active IP Right Cessation
- 1997-04-04 CA CA002201808A patent/CA2201808A1/en not_active Abandoned
- 1997-04-04 JP JP9100765A patent/JPH1033973A/ja active Pending
- 1997-04-08 BR BR9701721A patent/BR9701721A/pt active Search and Examination
- 1997-04-08 TR TR97/00281A patent/TR199700281A2/xx unknown
- 1997-04-08 AR ARP970101392A patent/AR006566A1/es not_active Application Discontinuation
- 1997-04-08 CO CO97017865A patent/CO4520308A1/es unknown
- 1997-04-08 HU HU9700725A patent/HUP9700725A1/hu unknown
- 1997-04-09 PL PL97319399A patent/PL319399A1/xx unknown
- 1997-04-09 CN CN97109585A patent/CN1087185C/zh not_active Expired - Fee Related
- 1997-04-09 RU RU97105693/12A patent/RU2191065C2/ru active
-
1999
- 1999-01-29 US US09/240,033 patent/US5955036A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE59705322D1 (de) | 2001-12-20 |
TR199700281A3 (tr) | 1997-10-21 |
RU2191065C2 (ru) | 2002-10-20 |
EP0800860A1 (de) | 1997-10-15 |
AR006566A1 (es) | 1999-09-08 |
EP0800860B1 (de) | 2001-11-14 |
CN1166375A (zh) | 1997-12-03 |
AU723590B2 (en) | 2000-08-31 |
BR9701721A (pt) | 1998-11-10 |
TR199700281A2 (xx) | 1997-10-21 |
MX9702466A (es) | 1998-04-30 |
AU1771797A (en) | 1997-10-16 |
CO4520308A1 (es) | 1997-10-15 |
US5955036A (en) | 1999-09-21 |
US5917081A (en) | 1999-06-29 |
JPH1033973A (ja) | 1998-02-10 |
CA2201808A1 (en) | 1997-10-09 |
HUP9700725A1 (hu) | 2000-05-28 |
HU9700725D0 (en) | 1997-05-28 |
CN1087185C (zh) | 2002-07-10 |
PL319399A1 (en) | 1997-10-13 |
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