ES2167581T3 - Composiciones y procedimientos para estabilizar polimeros. - Google Patents

Composiciones y procedimientos para estabilizar polimeros.

Info

Publication number
ES2167581T3
ES2167581T3 ES96922797T ES96922797T ES2167581T3 ES 2167581 T3 ES2167581 T3 ES 2167581T3 ES 96922797 T ES96922797 T ES 96922797T ES 96922797 T ES96922797 T ES 96922797T ES 2167581 T3 ES2167581 T3 ES 2167581T3
Authority
ES
Spain
Prior art keywords
compositions
procedures
stabilizing polymers
poly
strong
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96922797T
Other languages
English (en)
Inventor
Fu-Pao Tsao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Application granted granted Critical
Publication of ES2167581T3 publication Critical patent/ES2167581T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/49Phosphorus-containing compounds
    • C08K5/51Phosphorus bound to oxygen
    • C08K5/53Phosphorus bound to oxygen bound to oxygen and to carbon only
    • C08K5/5317Phosphonic compounds, e.g. R—P(:O)(OR')2

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Dental Preparations (AREA)

Abstract

FORMULACIONES Y METODOS PARA REDUCIR LA TASA DE DESINTEGRACION DE BIOADHESIVOS POLIMERICOS Y POTENCIADORES DE VISCOSIDAD, COMO ACIDOS POLIACRILICOS. LAS FORMULACIONES INCLUYEN POR LO MENOS UN AGENTE QUELANTE ESTABLE FUERTE, PREFERENTEMENTE UN COMPUESTO ORGANOFOSFORADO COMO EL ACIDO DIMETILEN NTAMETILENFOSFONICO. ESTAS FORMULACIONES BIOCOMPATIBLES SON ESPECIALMENTE UTILES EN EL AMBITO OFTALMICO.
ES96922797T 1995-06-22 1996-06-12 Composiciones y procedimientos para estabilizar polimeros. Expired - Lifetime ES2167581T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/493,761 US5683993A (en) 1995-06-22 1995-06-22 Compositions and methods for stabilizing polymers

Publications (1)

Publication Number Publication Date
ES2167581T3 true ES2167581T3 (es) 2002-05-16

Family

ID=23961593

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96922797T Expired - Lifetime ES2167581T3 (es) 1995-06-22 1996-06-12 Composiciones y procedimientos para estabilizar polimeros.

Country Status (13)

Country Link
US (2) US5683993A (es)
EP (1) EP0833609B1 (es)
JP (3) JP4260881B2 (es)
AT (1) ATE208189T1 (es)
AU (1) AU715686B2 (es)
CA (1) CA2222646C (es)
CY (1) CY2323B1 (es)
DE (1) DE69616791T2 (es)
DK (1) DK0833609T3 (es)
ES (1) ES2167581T3 (es)
PT (1) PT833609E (es)
TW (1) TW358109B (es)
WO (1) WO1997000669A1 (es)

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ES2174388T3 (es) * 1997-06-27 2002-11-01 Akzo Nobel Nv Solucion liquida de medicamento para administracion oral.
DE19744113A1 (de) * 1997-10-06 1999-04-15 Mann Gerhard Chem Pharm Fab Dexamethason-Gel
EP0938896A1 (en) * 1998-01-15 1999-09-01 Novartis AG Autoclavable pharmaceutical compositions containing a chelating agent
US5885550A (en) * 1998-07-02 1999-03-23 Vallier; Deandra K. Ophthalmic whitening solution
US6627660B1 (en) * 1999-11-16 2003-09-30 New River Pharmaceuticals Inc. Stabilized thyroxine compounds
DE60138832D1 (de) 2000-11-17 2009-07-09 Kyowa Hakko Kirin Co Ltd Expression xenogener (menschlicher) immunglobuline in geklonten, transgenen rindern
EP1480677B8 (en) * 2001-11-21 2012-05-23 Carl Zeiss Meditec SAS Composition for stabilizing hyaluronic acid
US20040115160A1 (en) * 2002-12-13 2004-06-17 Salamone Joseph C. Quaternary ammonium esters for disinfection and preservation
US20050084468A1 (en) * 2003-10-17 2005-04-21 Colgate-Palmolive Company Antimicrobial cleaning composition
CA2908828C (en) * 2006-03-17 2018-01-16 Johnson & Johnson Vision Care, Inc. Methods for stabilizing oxidatively unstable compositions
JP5160757B2 (ja) * 2006-09-01 2013-03-13 ホーユー株式会社 毛髪脱染剤組成物
US20100021561A1 (en) * 2006-09-21 2010-01-28 Chowhan Masood A Self-preserved aqueous pharmaceutical compositions
TWI394564B (zh) * 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
KR101421519B1 (ko) * 2006-09-28 2014-07-30 알콘 리서치, 리미티드 자기 보존 수성 약제학적 조성물
RU2445950C2 (ru) * 2006-10-26 2012-03-27 Сэндзю Фармасьютикал Ко., Лтд. Жидкая водная глазная композиция
CA2682100C (en) 2007-03-28 2017-11-21 University Of Iowa Research Foundation Transgenic animal models of disease
US8759321B2 (en) 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
US8119112B2 (en) 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
CA2717679C (en) * 2008-03-17 2013-07-23 Alcon Research, Ltd. Aqueous pharmaceutical compositions containing borate-polyol complexes
US20100298335A1 (en) * 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and Methods for Ameliorating or Reducing Presbyopia
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
TWI489997B (zh) 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸-多元醇錯合物之水性藥學組成物
RU2644673C2 (ru) 2011-05-16 2018-02-13 Дзе Кьюрейторз Оф Дзе Юниверсити Оф Миссури Животные, устойчивые к вирусу репродуктивно-респираторного синдрома свиней
DK2773952T3 (en) 2011-11-03 2019-04-23 Univ Iowa Res Found Transgenic pig models of cystic fibrosis
US20130177599A1 (en) * 2012-01-06 2013-07-11 Insite Vision Incorporated Methods and kits for extending contact lens use
KR101400791B1 (ko) 2012-10-04 2014-05-29 주식회사대성미생물연구소 동물용 복합 기능성 항생제 조성물
US10010502B2 (en) 2015-05-19 2018-07-03 Amorphex Therapeutics Llc Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation
US10413505B1 (en) 2017-02-07 2019-09-17 Genus Lifesciences Inc. Pharmaceutical compositions and methods of using the same
US10231961B1 (en) 2017-02-07 2019-03-19 Genus Lifesciences Inc. Pharmaceutical compositions and methods of using the same
US10149843B1 (en) 2017-02-07 2018-12-11 Gneus Lifescineces Inc. Pharmaceutical compositions and methods of using the same
CN109387622A (zh) * 2018-03-02 2019-02-26 国家纳米科学中心 一种高分子材料表面修饰方法及其应用

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US4303568A (en) * 1979-12-10 1981-12-01 Betz Laboratories, Inc. Corrosion inhibition treatments and method
US4474916A (en) * 1982-07-27 1984-10-02 Basf Aktiengesellschaft Concentrated aqueous solutions of mixtures of organic complexing agents and dispersing agents based on polymeric aliphatic carboxylic acids
ATE151286T1 (de) * 1983-11-14 1997-04-15 Columbia Lab Inc Bioadhäsive mittel
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US4540738A (en) * 1984-12-07 1985-09-10 The Kendall Company Acrylic adhesive composition comprising an alpha amino phosphonic acid or salt having improved stability
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US4812173A (en) * 1987-05-01 1989-03-14 Ciba-Geigy Corporation Stabilized hydrogen peroxide contact lens disinfecting solution
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
DE3805663A1 (de) * 1988-02-24 1989-09-07 Henkel Kgaa Oxaalkanpolyphosphonsaeuren, ihre verwendung als thresholder sowie diese verbindungen enthaltende, komplexierend wirkende zusammensetzungen
ATE262354T1 (de) * 1988-08-04 2004-04-15 Novartis Pharma Gmbh Verfahren zur konservierung ophthalmischer lösungen und zusammensetzungen dafür
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JP3107873B2 (ja) * 1991-09-26 2000-11-13 ユニ・チャーム株式会社 高吸水性ポリマーの経時着色防止方法および経時着色防止剤
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JP2873530B2 (ja) * 1991-12-13 1999-03-24 参天製薬株式会社 ニュートン型粘性を示すカルボキシビニルポリマー含有点眼液基剤
DE4209722C3 (de) * 1992-03-25 1997-06-19 Medproject Pharma Entwicklungs Tropfbares Gel für die Augenheilkunde
SE500660C2 (sv) * 1992-12-03 1994-08-01 Mo Och Domsjoe Ab Förfarande för framställning av grönlut vid kemikalieåtervinning i sulfat- och sulfitmassafabriker
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
EP0638685B1 (de) * 1993-08-10 1998-12-23 Ciba SC Holding AG Mercerisiernetzmittel
FR2726762B1 (fr) * 1994-11-10 1997-01-17 Oreal Composition cosmetique ou dermatologique sous forme d'une dispersion d'une phase huileuse dans une phase aqueuse stabilisee a l'aide de particules de gel cubique et son procede d'obtention
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds

Also Published As

Publication number Publication date
EP0833609A1 (en) 1998-04-08
DK0833609T3 (da) 2002-02-18
JP4260881B2 (ja) 2009-04-30
CA2222646A1 (en) 1997-01-09
TW358109B (en) 1999-05-11
US5683993A (en) 1997-11-04
CA2222646C (en) 2009-12-08
DE69616791T2 (de) 2002-05-29
AU715686B2 (en) 2000-02-10
EP0833609B1 (en) 2001-11-07
US5858996A (en) 1999-01-12
ATE208189T1 (de) 2001-11-15
JP2012153710A (ja) 2012-08-16
AU6355196A (en) 1997-01-22
DE69616791D1 (de) 2001-12-13
PT833609E (pt) 2002-04-29
WO1997000669A1 (en) 1997-01-09
JP2008248246A (ja) 2008-10-16
JPH11510480A (ja) 1999-09-14
CY2323B1 (en) 2003-11-14

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