ES2165278B1 - A PROCEDURE FOR OBTAINING GLYCOSILATED PRODUCTS THROUGH THE BIOSYNTHESIS OF THE DEOXIAZUCAR: L-OLIVE, L-OLEANDROSA AND L-RAMNOSA. - Google Patents

A PROCEDURE FOR OBTAINING GLYCOSILATED PRODUCTS THROUGH THE BIOSYNTHESIS OF THE DEOXIAZUCAR: L-OLIVE, L-OLEANDROSA AND L-RAMNOSA.

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Publication number
ES2165278B1
ES2165278B1 ES9901435A ES9901435A ES2165278B1 ES 2165278 B1 ES2165278 B1 ES 2165278B1 ES 9901435 A ES9901435 A ES 9901435A ES 9901435 A ES9901435 A ES 9901435A ES 2165278 B1 ES2165278 B1 ES 2165278B1
Authority
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Spain
Prior art keywords
oleandrosa
biosynthesis
obtaining
products
deoxiazucar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn - After Issue
Application number
ES9901435A
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Spanish (es)
Other versions
ES2165278A1 (en
Inventor
Gonzalez Ignaci Agirrezabalaga
Alvarez Carlos Olano
Vega Nerea Allende
Garcia Leticia Rodriguez
Brana Alfredo Fernandez
Fernandez Carmen Mendez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Oviedo
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Universidad de Oviedo
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Filing date
Publication date
Application filed by Universidad de Oviedo filed Critical Universidad de Oviedo
Priority to ES9901435A priority Critical patent/ES2165278B1/en
Publication of ES2165278A1 publication Critical patent/ES2165278A1/en
Application granted granted Critical
Publication of ES2165278B1 publication Critical patent/ES2165278B1/en
Anticipated expiration legal-status Critical
Withdrawn - After Issue legal-status Critical Current

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  • Enzymes And Modification Thereof (AREA)

Abstract

Se describe un procedimiento de obtención de productos glicosilados a través de la construcción de tres plásmidos capaces de dirigir la biosíntesis de los desoxiazúcares L- olivosa, L-oleandrosa y L-ramnosa. Se describe también la construcción de una cepa de Streptomyces albus que posee integrado en su cromosoma el gen de resistencia a eritromicina y un gen (oleGII) que codifica una glicosiltransferasa que la capacita para glicosilar anillos macrocíclicos lactona.A process for obtaining glycosylated products is described through the construction of three plasmids capable of directing the biosynthesis of the deoxyazers L-olivosa, L-oleandrosa and L-rhamnose. The construction of a strain of Streptomyces albus, which has an integrated erythromycin resistance gene and a gene (oleGII) that encodes a glycosyltransferase that enables it to glycosylate macrocyclic lactone rings, is also described.

ES9901435A 1999-06-24 1999-06-24 A PROCEDURE FOR OBTAINING GLYCOSILATED PRODUCTS THROUGH THE BIOSYNTHESIS OF THE DEOXIAZUCAR: L-OLIVE, L-OLEANDROSA AND L-RAMNOSA. Withdrawn - After Issue ES2165278B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES9901435A ES2165278B1 (en) 1999-06-24 1999-06-24 A PROCEDURE FOR OBTAINING GLYCOSILATED PRODUCTS THROUGH THE BIOSYNTHESIS OF THE DEOXIAZUCAR: L-OLIVE, L-OLEANDROSA AND L-RAMNOSA.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES9901435A ES2165278B1 (en) 1999-06-24 1999-06-24 A PROCEDURE FOR OBTAINING GLYCOSILATED PRODUCTS THROUGH THE BIOSYNTHESIS OF THE DEOXIAZUCAR: L-OLIVE, L-OLEANDROSA AND L-RAMNOSA.

Publications (2)

Publication Number Publication Date
ES2165278A1 ES2165278A1 (en) 2002-03-01
ES2165278B1 true ES2165278B1 (en) 2003-06-16

Family

ID=8309006

Family Applications (1)

Application Number Title Priority Date Filing Date
ES9901435A Withdrawn - After Issue ES2165278B1 (en) 1999-06-24 1999-06-24 A PROCEDURE FOR OBTAINING GLYCOSILATED PRODUCTS THROUGH THE BIOSYNTHESIS OF THE DEOXIAZUCAR: L-OLIVE, L-OLEANDROSA AND L-RAMNOSA.

Country Status (1)

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ES (1) ES2165278B1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998194A (en) * 1995-12-21 1999-12-07 Abbott Laboratories Polyketide-associated sugar biosynthesis genes
EP1032679A2 (en) * 1997-07-25 2000-09-06 Hoechst Marion Roussel Genes for biosynthesis and transfer of 6-deoxy-hexoses in saccharopolyspora erythrea and streptomyces antibioticus and uses thereof

Also Published As

Publication number Publication date
ES2165278A1 (en) 2002-03-01

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