ES2164647T3 - Sistema y procedimiento de analisis de liquidos de muestra de direccion reversible. - Google Patents

Sistema y procedimiento de analisis de liquidos de muestra de direccion reversible.

Info

Publication number
ES2164647T3
ES2164647T3 ES93102323T ES93102323T ES2164647T3 ES 2164647 T3 ES2164647 T3 ES 2164647T3 ES 93102323 T ES93102323 T ES 93102323T ES 93102323 T ES93102323 T ES 93102323T ES 2164647 T3 ES2164647 T3 ES 2164647T3
Authority
ES
Spain
Prior art keywords
sample
liquid
conduct
analysis
liquids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES93102323T
Other languages
English (en)
Inventor
George Zabetakis
Paul G Gherson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of ES2164647T3 publication Critical patent/ES2164647T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/45—Magnetic mixers; Mixers with magnetically driven stirrers
    • B01F33/451—Magnetic mixers; Mixers with magnetically driven stirrers wherein the mixture is directly exposed to an electromagnetic field without use of a stirrer, e.g. for material comprising ferromagnetic particles or for molten metal
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/11—Automated chemical analysis
    • Y10T436/117497—Automated chemical analysis with a continuously flowing sample or carrier stream
    • Y10T436/118339—Automated chemical analysis with a continuously flowing sample or carrier stream with formation of a segmented stream

Landscapes

  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

SE PONE A DISPOSICION UN APARATO (20) DE ANALISIS DE LIQUIDO DE MUESTRA Y UN METODO QUE COMPRENDE LA FORMACION Y SUMINISTRO A UN CONDUCTO (134) DE UNA CORRIENTE DE SUCESIVOS ENVASES (TP1, TP2) DE PRUEBA DE LIQUIDOS DE MUESTRA, Y EL DESPLAZAMIENTO BIDIRECCIONAL REPETIDO DE LA CORRIENTE DE ENVASES DE LIQUIDO DE MUESTRA EN EL CONDUCTO A TRAVES DE UNO O UNA PLURALIDAD DE APARATOS (138,244) DE ANALISIS DE LIQUIDO DE MUESTRA COLOCADOS DE FORMA ESPACIADA, QUE ESTAN ASOCIADOS DE FORMA OPERATIVA CON EL CONDUCTO DE LIQUIDO DE MUESTRA PARA SUMINISTRAR O PARA REPETIR LOS ANALISIS EN EL TIEMPO ESPACIADO EN UNA CIRCULACION DE LOS LIQUIDOS DE MUESTRA EN CADA UNO DE LOS ENVASES DE PRUEBA DE ESTE LIQUIDO DE MUESTRA. CADA UNO DE LOS ENVASES (TP1) COMPRENDE UN PRIMER SEGMENTO DE UN LIQUIDO (S1) DE MUESTRA Y PRIMER LIQUIDO (R1) REACTIVO, Y UN SEGMENTO DE UN SEGUNDO LIQUIDO (R2) REACTIVO ESPACIADO CON RESPECTO AL PRIMER SEGMENTO POR MEDIO DE UN FLUIDO (A3) DIFERENTE EN EL ENVASE DE PRUEBA. EL CONDUCTO (134) INCLUYE UNA PARTE (140) QUE ES OPERABLE PARA COMBINAR LOS RESPECTIVOS SEGMENTOS PRIMERO Y SEGUNDO DE CADA UNO DE LOS ENVASES A TRAVES DEL FLUJO DE LOS MISMOS A FIN DE COMENZAR LA MUESTRA Y LOS LIQUIDOS REACTIVOS PARA LA REACCION SEGUN EL ANALISIS DEL LIQUIDO CORRESPONDIENTE; Y EL, O AL MENOS UNO DE LOS APARATOS (138) DE ANALISIS ESTA DISPUESTO AGUAS ARRIBA EN EL CONDUCTO EN SU PARTE CORRESPONDIENTE PARA PERMITIR ANALISIS INDEPENDIENTES DE LOS RESPECTIVOS PRIMER Y SEGUNDO SEGMENTOS DE LOS ENVASES EN CIRCULACION ANTES DE SU COMBINACION. SE OPERA DE FORMA PRECISA, CON BOMBEO (100,280) DE DESPLAZAMIENTO POSITIVO EN FORMA OPERACIONAL ASOCIADA CON LA ENTRADA DEL CONDUCTO O TANTO CON LA ENTRADA COMO CON LA SALIDA Y, EN CADA ACONTECIMIENTO, ACOPLADO DE FORMA PRECISA PARA SUMINISTRAR LOS BOMBEOS DIFERENCIALES, SIENDO UTILIZADO PARA LA FORMACION Y SUMINISTRO DE LOS ENVASES EN CIRCULACION AL CONDUCTO A FIN DE FORMAR LA CORRIENTE DE ENVASES DE LIQUIDO DE MUESTRA, Y PARA EL DESPLAZAMIENTO BIDIRECCIONAL REPETIDO DE LA CORRIENTE EN EL CONDUCTO. UN LIQUIDO (IL) AISLANTE QUE ES INMISCIBLE CON LA MUESTRA Y CON LOS LIQUIDOS REACTIVOS, Y CON EL CUAL SE HUMEDECE PREFERENTEMENTE LAS PAREDES DEL CONDUCTO PARA LA EXCLUSION SUSTANCIAL DE ESTOS LIQUIDOS, SE INTRODUCE EN ESTE CONDUCTO A FIN DE MINIMIZAR LA ADHERENCIA DE LOS LIQUIDOS DE MUESTRA, CON ELLO SE MINIMIZA EL ARRASTRE DEL LIQUIDO DE MUESTRA, Y SE MAXIMIZA LA EXACTITUD DEL ANALISIS DE LOS LIQUIDOS DE MUESTRA.
ES93102323T 1992-02-26 1993-02-15 Sistema y procedimiento de analisis de liquidos de muestra de direccion reversible. Expired - Lifetime ES2164647T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/846,269 US5268147A (en) 1992-02-26 1992-02-26 Reversible direction capsule chemistry sample liquid analysis system and method

Publications (1)

Publication Number Publication Date
ES2164647T3 true ES2164647T3 (es) 2002-03-01

Family

ID=25297402

Family Applications (1)

Application Number Title Priority Date Filing Date
ES93102323T Expired - Lifetime ES2164647T3 (es) 1992-02-26 1993-02-15 Sistema y procedimiento de analisis de liquidos de muestra de direccion reversible.

Country Status (9)

Country Link
US (1) US5268147A (es)
EP (1) EP0562260B1 (es)
JP (1) JP3256818B2 (es)
AU (1) AU653486B2 (es)
CA (1) CA2083322C (es)
DE (1) DE69331075T2 (es)
DK (1) DK0562260T3 (es)
ES (1) ES2164647T3 (es)
IL (1) IL103782A (es)

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Also Published As

Publication number Publication date
EP0562260A2 (en) 1993-09-29
AU653486B2 (en) 1994-09-29
JP3256818B2 (ja) 2002-02-18
DK0562260T3 (da) 2002-02-25
CA2083322A1 (en) 1993-08-27
DE69331075T2 (de) 2002-03-21
AU2984092A (en) 1993-09-02
US5268147A (en) 1993-12-07
IL103782A0 (en) 1993-04-04
EP0562260A3 (es) 1994-02-23
JPH0658942A (ja) 1994-03-04
DE69331075D1 (de) 2001-12-13
EP0562260B1 (en) 2001-11-07
CA2083322C (en) 2004-04-13
IL103782A (en) 1994-06-24

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