ES2164076T3 - Aparato para preparacion y carga automaticas de muestras. - Google Patents

Aparato para preparacion y carga automaticas de muestras.

Info

Publication number
ES2164076T3
ES2164076T3 ES94114927T ES94114927T ES2164076T3 ES 2164076 T3 ES2164076 T3 ES 2164076T3 ES 94114927 T ES94114927 T ES 94114927T ES 94114927 T ES94114927 T ES 94114927T ES 2164076 T3 ES2164076 T3 ES 2164076T3
Authority
ES
Spain
Prior art keywords
sample
incubation
reagent
tube
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94114927T
Other languages
English (en)
Inventor
Kenneth F Uffenheimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of ES2164076T3 publication Critical patent/ES2164076T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/00722—Communications; Identification
    • G01N35/00732—Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742—Type of codes
    • G01N2035/00752—Type of codes bar codes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1032—Dilution or aliquotting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • G01N2035/1086—Cylindrical, e.g. variable angle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

UN SISTEMA AUTOMATIZADO PARA PREPARAR MUESTRAS, Y ENTONCES CARGAR LAS MUESTRAS A UN ANALIZADOR QUE INCLUYE UN CARRUSEL PARA MUESTRA QUE COMBINA Y HACE ROTAR UNA PLURALIDAD DE TUBOS DE ENSAYO PARA UNA ESTACION DE ASPIRACION. UNA MUESTRA ES ASPIRADA DESDE EL TUBO, Y DIRIGIDA A LO LARGO CON UN REACTIVO DE ENSAYO EN UN TUBO DE INCUBACION. UNA PLURALIDAD DE TUBOS DE INCUBACION ESTAN INCLUIDOS SOBRE UN CARRUSEL DE TUBOS DE INCUBACION, Y UNA SONDA REACTIVA ASPIRA UN REACTIVO Y DISPENSA EL REACTIVO A LO LARGO CON LA MUESTRA DENTRO DEL TUBO DE INCUBACION. UN TUBO DE INCUBACION ES CONTINUAMENTE ROTADO PARA UNA SONDA DE INYECCION QUE ELIMINA UNA PORCION DE LA MUESTRA Y REACTIVO DESPUES DE QUE LA MUESTRA HAYA TENIDO TIEMPO PARA INCUBAR. LA SONDA DE INYECCION LIBERA LA MUESTRA RETIRADA A UNA PUERTA DE INYECCION PARA UN SISTEMA DE ANALISIS. EL SISTEMA DE ANALISIS UTILIZA UNA TECNICA DE PRUEBA CONOCIDA PARA PROBAR LA MUESTRA. EL SISTEMA PUEDE INCLUIR UNA ESTACION PARA DISPENSAR UN AGENTE CAUSANTE DE LISISO UN AGENTE DE AMORTIGUACION EN EL TUBO DE INCUBACION DESPUES QUE LA SONDA REACTIVA HAYA DISPENSADO EL REACTIVO Y MUESTRA DENTRO DEL TUBO DE INCUBACION, Y ANTES QUE LA SONDA DE INYECCION RETIRE LA MUESTRA. ESTACIONES DE LAVADO ESTAN DISPUESTAS PARA LAVAR LAS DIVERSAS SONDAS. ADICIONALMENTE, SONDAS DE LAVADO SON INCLUIDAS PARA LAVAR LOS TUBOS DE INCUBACION DESPUES QUE LA MUESTRA HAYA SIDO RETIRADA POR LA SONDA DE PRUEBA. POR CONSIGUIENTE, EL SISTEMA PUEDE OPERAR AUTOMATICAMENTE Y CONTINUAMENTE PARA RETIRAR MUESTRAS DE DICHOS TUBOS DE MUESTRA, PREPARAR MUESTRAS EN EL TUBO DE INCUBACION, Y ESTAS MUESTRAS A UN ANALIZADOR. LOS TUBOS DE INCUBACION DE MUESTRA SON LIMPIADOS PARA REUTILIZACION. EN OTRA CARACTERISTICA DE LA INVENCION, UNA BOMBA PARA IMPULSAR EL REACTIVO Y LA MUESTRA DENTRO DEL TUBO DE INCUBACION INCLUYE UNA CONEXION PARA AIRE QUE FACILITA EL MOVIMIENTO DE LOS FLUIDOS DENTRO DE LOS TUBOS DE INCUBACION.
ES94114927T 1993-09-29 1994-09-22 Aparato para preparacion y carga automaticas de muestras. Expired - Lifetime ES2164076T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12923793A 1993-09-29 1993-09-29

Publications (1)

Publication Number Publication Date
ES2164076T3 true ES2164076T3 (es) 2002-02-16

Family

ID=22439037

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94114927T Expired - Lifetime ES2164076T3 (es) 1993-09-29 1994-09-22 Aparato para preparacion y carga automaticas de muestras.

Country Status (3)

Country Link
EP (1) EP0645631B1 (es)
DE (1) DE69429230T2 (es)
ES (1) ES2164076T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPN762196A0 (en) * 1996-01-17 1996-02-08 Australian Biomedical Corporation Limited Specimen preparation apparatus
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
FI105784B (fi) * 1998-09-14 2000-10-13 Wallac Oy Menetelmä ja laite näytteen ottamiseksi suljetusta koeputkesta
DE10002475C1 (de) 2000-01-21 2001-05-31 Roche Diagnostics Gmbh Analysegerät zur Analyse von Proben
GB0004456D0 (en) 2000-02-26 2000-04-19 Glaxo Group Ltd Medicament dispenser
US6809804B1 (en) 2000-05-11 2004-10-26 Becton, Dickinson And Company System and method for providing improved event reading and data processing capabilities in a flow cytometer
GB0012465D0 (en) 2000-05-24 2000-07-12 Glaxo Group Ltd Monitoring method
GB0013619D0 (en) 2000-06-06 2000-07-26 Glaxo Group Ltd Sample container
BR0112481A (pt) 2000-07-15 2003-07-22 Glaxo Group Ltd Dispensador de medicamentos, kit de partes, e, sistema
JP2004535572A (ja) 2001-06-13 2004-11-25 ケニス エフ． ウーヘンハイマー， 自動化流体操作システムおよび方法
US7858040B2 (en) 2004-05-07 2010-12-28 Saryna Biotechnologies Llc Direct mixing and injection for high throughput fluidic systems
WO2005114224A1 (en) * 2004-05-07 2005-12-01 Novasite Pharmaceuticals, Inc. Direct mixing and injection for high throughput fluidic systems
CN101201349B (zh) * 2005-03-17 2011-10-12 希森美康株式会社 试料分析装置和试料分析方法以及血液分析装置
US9243993B2 (en) 2005-03-17 2016-01-26 Sysmex Corporation Sample analyzer and sample analyzing method
CN102879258A (zh) * 2011-07-15 2013-01-16 江苏美诚生物科技有限公司 新型试剂高效自动混匀装置
EP2817606B1 (en) 2012-02-24 2021-06-02 Instrunor AS Instrument for pretreating cell samples
CN102661888B (zh) * 2012-05-18 2014-07-30 山东美医林电子仪器有限公司 一种适用于血流变检测的全血自动层吸取样混匀方法及装置
JP6680610B2 (ja) * 2016-04-28 2020-04-15 シスメックス株式会社 前処理装置及び検体分析装置
WO2020076659A1 (en) * 2018-10-08 2020-04-16 Accure Health Inc. Automated assay processing methods and systems
CN109655627B (zh) * 2018-12-17 2024-06-25 宁波海壹生物科技有限公司 一种带孵育功能的清洗装置
CN111521772B (zh) * 2019-02-02 2021-12-07 深圳迎凯生物科技有限公司 液体分配方法和免疫分析方法
CN113219193B (zh) * 2020-01-21 2024-03-19 深圳迎凯生物科技有限公司 样本分析方法和样本分析装置

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FR2076797A5 (es) * 1970-01-28 1971-10-15 Girolami Antoine
JPS56154667A (en) * 1980-05-01 1981-11-30 Olympus Optical Co Ltd Partial injection
US4387076A (en) * 1981-10-14 1983-06-07 Coulter Electronics, Inc. Sample feeding arrangement
US4517302A (en) * 1982-11-15 1985-05-14 Technicon Instruments Corporation Continuous flow metering apparatus
WO1986002626A1 (en) * 1984-10-23 1986-05-09 Donald Earl Burg Snap-in cartridge diluter
US5133936A (en) * 1988-09-07 1992-07-28 Hitachi, Ltd. Constant-temperature air type automatic analysis apparatus
JPH0718785B2 (ja) * 1988-09-19 1995-03-06 株式会社日立製作所 フローセル装置
US5167926A (en) * 1989-09-13 1992-12-01 Kabushiki Kaisha Tiyoda Seisakusho Apparatus for pretreating cells for flow cytometry

Also Published As

Publication number Publication date
DE69429230D1 (de) 2002-01-10
EP0645631A2 (en) 1995-03-29
EP0645631A3 (en) 1996-02-07
EP0645631B1 (en) 2001-11-28
DE69429230T2 (de) 2002-07-18

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