ES2163283T3 - Composiciones farmaceuticas que contienen un inhibidor de la reductasa de aldosa y un inhibidor de la ace. - Google Patents
Composiciones farmaceuticas que contienen un inhibidor de la reductasa de aldosa y un inhibidor de la ace.Info
- Publication number
- ES2163283T3 ES2163283T3 ES98932358T ES98932358T ES2163283T3 ES 2163283 T3 ES2163283 T3 ES 2163283T3 ES 98932358 T ES98932358 T ES 98932358T ES 98932358 T ES98932358 T ES 98932358T ES 2163283 T3 ES2163283 T3 ES 2163283T3
- Authority
- ES
- Spain
- Prior art keywords
- inhibitor
- pharmaceutical compositions
- compositions containing
- aldosa
- ace
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title 2
- 229940118148 Aldose reductase inhibitor Drugs 0.000 abstract 1
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 208000007342 Diabetic Nephropathies Diseases 0.000 abstract 1
- 208000032131 Diabetic Neuropathies Diseases 0.000 abstract 1
- 206010012689 Diabetic retinopathy Diseases 0.000 abstract 1
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 208000033679 diabetic kidney disease Diseases 0.000 abstract 1
- 239000002532 enzyme inhibitor Substances 0.000 abstract 1
- 229940125532 enzyme inhibitor Drugs 0.000 abstract 1
- MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La invención se refiere a una composiciones farmacéuticas que contienen un inhibidor de la reductasa de la aldosa y un inhibidor de la enzima de la conversión, y su utilización en el tratamiento de las complicaciones de la diabetes, como la neuropatía diabética, la retinopatía diabética y la nefropatía diabética.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9714274.9A GB9714274D0 (en) | 1997-07-08 | 1997-07-08 | Pharmaceutical composition |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2163283T3 true ES2163283T3 (es) | 2002-01-16 |
Family
ID=10815469
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98932358T Expired - Lifetime ES2163283T3 (es) | 1997-07-08 | 1998-07-02 | Composiciones farmaceuticas que contienen un inhibidor de la reductasa de aldosa y un inhibidor de la ace. |
Country Status (28)
Country | Link |
---|---|
US (1) | US6337327B1 (es) |
EP (1) | EP0991424B1 (es) |
JP (1) | JP2002509540A (es) |
KR (1) | KR20010015551A (es) |
CN (1) | CN1186097C (es) |
AT (1) | ATE205402T1 (es) |
AU (1) | AU746211B2 (es) |
BR (1) | BR9810570A (es) |
CA (1) | CA2292451A1 (es) |
CZ (1) | CZ290276B6 (es) |
DE (1) | DE69801661T2 (es) |
DK (1) | DK0991424T3 (es) |
ES (1) | ES2163283T3 (es) |
GB (1) | GB9714274D0 (es) |
HK (1) | HK1028876A1 (es) |
HU (1) | HU224009B1 (es) |
ID (1) | ID24597A (es) |
IL (1) | IL133004A (es) |
NO (1) | NO20000045D0 (es) |
NZ (1) | NZ501165A (es) |
PL (1) | PL337925A1 (es) |
PT (1) | PT991424E (es) |
RU (1) | RU2216354C2 (es) |
SK (1) | SK122000A3 (es) |
TR (1) | TR199903026T2 (es) |
UA (1) | UA64761C2 (es) |
WO (1) | WO1999002189A1 (es) |
ZA (1) | ZA985993B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6642268B2 (en) * | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
US6221897B1 (en) * | 1998-06-10 | 2001-04-24 | Aventis Pharma Deutschland Gmbh | Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use |
GB0001662D0 (en) * | 1999-02-06 | 2000-03-15 | Zeneca Ltd | Pharmaceutical compositions |
US6426341B1 (en) * | 1999-06-30 | 2002-07-30 | Pfizer Inc. | Treatment for diabetic complications |
WO2001064205A2 (en) * | 2000-03-02 | 2001-09-07 | The Institutes For Pharmaceutical Discovery, Llc | Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor |
US20080058424A1 (en) * | 2002-05-23 | 2008-03-06 | Cephalon, Inc. | Novel pharmaceutical formulations of modafinil |
US20050203169A1 (en) * | 2001-08-06 | 2005-09-15 | Moskowitz David W. | Methods and compositions for treating diseases associated with excesses in ACE |
JP2005503378A (ja) * | 2001-08-06 | 2005-02-03 | ジエノメツド・エル・エル・シー | Aceの過剰に関連する疾患の治療方法及び組成物 |
AU2002352145A1 (en) * | 2001-11-26 | 2003-06-10 | Bayer Healthcare Ag | Regulation of human aldose reductase-like protein |
US7071210B2 (en) * | 2002-07-02 | 2006-07-04 | Pfizer Inc. | CETP inhibitors in combination with antihypertensive agents and uses thereof |
US20040116532A1 (en) | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
DK2771003T3 (en) | 2011-10-28 | 2017-07-17 | Lumena Pharmaceuticals Llc | Bile acid recycling inhibitors for the treatment of pediatric cholestatic liver disease |
US20150197536A1 (en) * | 2012-07-28 | 2015-07-16 | The Regents Of The University Of Colorado, A Body Corporate | Compounds reducing the production of sorbitol in the eye and methods of using the same |
CN103063794B (zh) * | 2012-12-24 | 2014-08-06 | 扬子江药业集团南京海陵药业有限公司 | 一种依帕司他片的含量检测控制方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9016978D0 (en) | 1990-08-02 | 1990-09-19 | Ici Plc | Acetamide derivatives |
AU711482B2 (en) * | 1994-06-28 | 1999-10-14 | Scotia Holdings Plc | Compositions for treatment of diabetic complications |
-
1997
- 1997-07-08 GB GBGB9714274.9A patent/GB9714274D0/en active Pending
-
1998
- 1998-02-07 UA UA2000020652A patent/UA64761C2/uk unknown
- 1998-07-02 EP EP98932358A patent/EP0991424B1/en not_active Expired - Lifetime
- 1998-07-02 ES ES98932358T patent/ES2163283T3/es not_active Expired - Lifetime
- 1998-07-02 DK DK98932358T patent/DK0991424T3/da active
- 1998-07-02 AU AU82296/98A patent/AU746211B2/en not_active Ceased
- 1998-07-02 NZ NZ501165A patent/NZ501165A/en unknown
- 1998-07-02 AT AT98932358T patent/ATE205402T1/de not_active IP Right Cessation
- 1998-07-02 PL PL98337925A patent/PL337925A1/xx unknown
- 1998-07-02 WO PCT/GB1998/001959 patent/WO1999002189A1/en not_active Application Discontinuation
- 1998-07-02 CA CA002292451A patent/CA2292451A1/en not_active Abandoned
- 1998-07-02 TR TR1999/03026T patent/TR199903026T2/xx unknown
- 1998-07-02 PT PT98932358T patent/PT991424E/pt unknown
- 1998-07-02 JP JP50831099A patent/JP2002509540A/ja active Pending
- 1998-07-02 US US09/462,353 patent/US6337327B1/en not_active Expired - Fee Related
- 1998-07-02 RU RU2000102888/14A patent/RU2216354C2/ru not_active IP Right Cessation
- 1998-07-02 DE DE69801661T patent/DE69801661T2/de not_active Expired - Fee Related
- 1998-07-02 BR BR9810570-1A patent/BR9810570A/pt not_active IP Right Cessation
- 1998-07-02 ID IDW991606A patent/ID24597A/id unknown
- 1998-07-02 SK SK12-2000A patent/SK122000A3/sk unknown
- 1998-07-02 CZ CZ200017A patent/CZ290276B6/cs not_active IP Right Cessation
- 1998-07-02 HU HU0002644A patent/HU224009B1/hu not_active IP Right Cessation
- 1998-07-02 IL IL13300498A patent/IL133004A/en not_active IP Right Cessation
- 1998-07-02 CN CNB988069199A patent/CN1186097C/zh not_active Expired - Fee Related
- 1998-07-02 KR KR1020007000055A patent/KR20010015551A/ko not_active Application Discontinuation
- 1998-07-07 ZA ZA985993A patent/ZA985993B/xx unknown
-
2000
- 2000-01-06 NO NO20000045A patent/NO20000045D0/no unknown
- 2000-09-22 HK HK00106011A patent/HK1028876A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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