ES2162019T3 - Procedimiento para preparar 4,6-dicloro-pirimidina. - Google Patents

Procedimiento para preparar 4,6-dicloro-pirimidina.

Info

Publication number
ES2162019T3
ES2162019T3 ES96900039T ES96900039T ES2162019T3 ES 2162019 T3 ES2162019 T3 ES 2162019T3 ES 96900039 T ES96900039 T ES 96900039T ES 96900039 T ES96900039 T ES 96900039T ES 2162019 T3 ES2162019 T3 ES 2162019T3
Authority
ES
Spain
Prior art keywords
pct
dicloro
pyrimidine
prepare
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96900039T
Other languages
English (en)
Inventor
Raymond Vincent Heavon Jones
Alan John Whitton
Ewan Campbell Boyd
David John Ritchie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Ltd
Original Assignee
Syngenta Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9501738.0A external-priority patent/GB9501738D0/en
Priority claimed from GBGB9507787.1A external-priority patent/GB9507787D0/en
Priority claimed from GBGB9510751.2A external-priority patent/GB9510751D0/en
Application filed by Syngenta Ltd filed Critical Syngenta Ltd
Application granted granted Critical
Publication of ES2162019T3 publication Critical patent/ES2162019T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

UN PROCEDIMIENTO PARA PREPARAR 4,6-DICLOROPIRIMIDINA QUE CONSISTE EN TRATAR 4,6-DIHIDROXIPIRIMIDINA CON OXICLORURO DE FOSFORO EN PRESENCIA DE UNA AMINA TRABADA SATURADA, LA SAL DE HIDROCLORURO DE UNA AMINA TRABADA SATURADA, O UN ANILLO QUE CONTIENE NITROGENO DE 5 ELEMENTOS INSATURADOS O UNA MEZCLA DE ESTOS, Y SEPARAR 4,6-DICLOROPIRIMIDINA DE LA MEZCLA DE REACCION ASI OBTENIDA.
ES96900039T 1995-01-30 1996-01-04 Procedimiento para preparar 4,6-dicloro-pirimidina. Expired - Lifetime ES2162019T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9501738.0A GB9501738D0 (en) 1995-01-30 1995-01-30 Chemical process
GBGB9507787.1A GB9507787D0 (en) 1995-04-13 1995-04-13 Chemical process
GBGB9510751.2A GB9510751D0 (en) 1995-05-26 1995-05-26 Chemical process

Publications (1)

Publication Number Publication Date
ES2162019T3 true ES2162019T3 (es) 2001-12-16

Family

ID=27267567

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96900039T Expired - Lifetime ES2162019T3 (es) 1995-01-30 1996-01-04 Procedimiento para preparar 4,6-dicloro-pirimidina.

Country Status (15)

Country Link
US (1) US6018045A (es)
EP (1) EP0807106B1 (es)
JP (1) JP3930903B2 (es)
KR (1) KR100406481B1 (es)
CN (1) CN1137099C (es)
AT (1) ATE207059T1 (es)
BR (1) BR9606817A (es)
DE (1) DE69616027T2 (es)
ES (1) ES2162019T3 (es)
GR (1) GR3036925T3 (es)
IL (1) IL116721A (es)
IN (1) IN184958B (es)
PT (1) PT807106E (es)
TW (1) TW343970B (es)
WO (1) WO1996023776A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9002375D0 (en) * 1990-02-02 1990-04-04 Pfizer Ltd Triazole antifungal agents
DE19531299A1 (de) * 1995-08-25 1997-02-27 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen
GB9709810D0 (en) * 1997-05-14 1997-07-09 Zeneca Ltd Chemical process
DE19730224A1 (de) * 1997-07-15 1999-01-21 Bayer Ag Verfahren zur Reinigung Phosphoroxychlorid
US6066734A (en) * 1997-12-19 2000-05-23 Dow Agrosciences Llc Chloropyrimidine process
DE19929353A1 (de) 1999-06-26 2000-12-28 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin
DE19929350A1 (de) 1999-06-26 2000-12-28 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Säurechloriden
DE19935322A1 (de) 1999-07-28 2001-02-01 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Phosgen
US6608199B2 (en) 2000-07-07 2003-08-19 Syngenta Limited Synthesis of chlorinated pyrimidines
US6982331B2 (en) * 2001-06-08 2006-01-03 Syngenta Crop Protection, Inc. Synthesis of chlorinated pyrimidines
CN107324300A (zh) * 2013-09-13 2017-11-07 重庆紫光化工股份有限公司 一种含磷废液的体系
CN103482592B (zh) * 2013-09-13 2016-09-28 重庆紫光化工股份有限公司 一种含磷废液的处理方法
CN103450094B (zh) * 2013-09-13 2015-08-26 重庆紫光化工股份有限公司 一种4,6-二氯嘧啶的纯化方法
CN106187912A (zh) * 2016-07-19 2016-12-07 安徽广信农化股份有限公司 一种4,6‑二氯嘧啶的生产工艺
CN106045917A (zh) * 2016-07-19 2016-10-26 安徽广信农化股份有限公司 一步法制备4,6‑二氯嘧啶的合成工艺
CN111635367B (zh) * 2020-06-24 2023-05-30 山东京博农化科技股份有限公司 一种4,6-二氯嘧啶的纯化方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789763A (fr) * 1971-10-08 1973-04-06 Ciba Geigy Procede de regeneration de l'oxychlorure ou -bromure de phosphore a partir de melanges reactionnels
DE3228712A1 (de) * 1982-07-31 1984-02-02 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4,5,6-tetrachlorpyrimidin
DE3431698A1 (de) * 1984-08-29 1986-03-13 Bayer Ag, 5090 Leverkusen 5,5-dichlor-4,5-dihydro-6-hydroxy-2-trichlormethyl-pyrimidin-4-on, ein verfahren zu seiner herstellung und seine verwendung
DE3441789A1 (de) * 1984-11-15 1986-05-15 Bayer Ag, 5090 Leverkusen 5,6-dichlor-4-hydroxy-2-trichlormethylpyrimidin
DE3441935A1 (de) * 1984-11-16 1986-05-28 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 2,4-dihydroxypyrimidinen
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
CA2091986C (en) * 1990-10-09 1995-11-28 Andrew Thurkauf Certain cycloalkyl and azacycloalkyl pyrrolopyrimidines; a new class of gaba brain receptor ligands
DE4222518A1 (de) * 1992-07-09 1994-01-13 Bayer Ag Verfahren zur Hertellung von 5-(Trifluormethyl)-uracil und die neuen Verbindungen 2,4-Dichlor-5-trichlormethyl-pyrimidin und 2,4-Difluor-5-trifluormethyl-pyrimidin
GB9220585D0 (en) * 1992-09-30 1992-11-11 Smithkline Beecham Plc Pharmaceuticals
CN1082031A (zh) * 1993-05-20 1994-02-16 郑州市孝义制药厂 磺胺间甲氧嘧啶的制备方法
DE4408404A1 (de) * 1994-03-12 1995-09-14 Huels Chemische Werke Ag Verfahren zur Herstellung von Chlorpyrimidinen
DE4429466A1 (de) * 1994-08-19 1996-02-22 Bayer Ag Verfahren zur Herstellung von Polychlorpyrimidinen
AT402818B (de) * 1995-06-02 1997-09-25 Chemie Linz Gmbh Verfahren zur herstellung von reinem 4,6-dichlorpyrimidin
DE19531299A1 (de) * 1995-08-25 1997-02-27 Bayer Ag Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen

Also Published As

Publication number Publication date
KR19980701747A (ko) 1998-06-25
JPH11507909A (ja) 1999-07-13
IL116721A0 (en) 1996-08-04
EP0807106B1 (en) 2001-10-17
BR9606817A (pt) 1997-12-30
EP0807106A1 (en) 1997-11-19
PT807106E (pt) 2002-02-28
CN1206408A (zh) 1999-01-27
TW343970B (en) 1998-11-01
DE69616027D1 (de) 2001-11-22
ATE207059T1 (de) 2001-11-15
IL116721A (en) 2000-02-17
WO1996023776A1 (en) 1996-08-08
KR100406481B1 (ko) 2004-03-24
CN1137099C (zh) 2004-02-04
DE69616027T2 (de) 2002-05-16
IN184958B (es) 2000-10-07
JP3930903B2 (ja) 2007-06-13
GR3036925T3 (en) 2002-01-31
US6018045A (en) 2000-01-25

Similar Documents

Publication Publication Date Title
ES2162019T3 (es) Procedimiento para preparar 4,6-dicloro-pirimidina.
ES2132921T3 (es) Un procedimiento para preparar piridin-2,6-diaminas.
IL117848A0 (en) Novel compounds a process for their production and pharmacetical compositions containing same
HK1001973A1 (en) Sulfonamides
UA35557C2 (uk) Похідні 1,2,4-оксадіазолілфеноксіалкілізоксазолу, що мають противірусну активність та фармацевтична композиція на їх основі
MY118828A (en) Substituted amino compounds and their use as substances having an analgesic effect
ATE112239T1 (de) Vaterit und verfahren zu dessen herstellung.
NO982778D0 (no) Morfinderivater med smertestillende virkning
AR004229A1 (es) Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos
NO171059C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive, disubstituerte benzylaminer
MX9604687A (es) Procedimiento para la preparacion de derivados de imidazo-benzodiacepina.
ES8607300A1 (es) Acidos 1,7-diamino-1,4-dihidro-4-oxo-3-(aza) quinolincarbo- xilicos
PL318460A1 (en) N-substituted derivatives of 3-azabicyclo [3.2.0] heptane, method of obtaining them and their application
ATE224719T1 (de) Phosphatidsäure enthaltende zusammensetzungen
ZA9510908B (en) Pharmaceutical compounds
DE59902666D1 (de) Edelfosin zur behandlung von hirntumoren
SE8904127D0 (sv) New biocyclic amino-substituted compounds
ES2149817T3 (es) Piridinas sustituidas, su preparacion y uso farmaceutico.
DE59908429D1 (de) Verfahren zur herstellung von (1r,4s)-2-azabicyclo 2.2.1 hept-5-en-3-on-derivaten
ATE150088T1 (de) Mikroorganismus und verfahren zur gewinnung von anthranilsäure
ES2163001T3 (es) Nuevos derivados de borneol, procedimiento para su preparacion y su utilizacion farmaceutica.
PL322847A1 (en) Condensed b-carbolins
SU1387399A1 (ru) Питательная среда для культивирования лептоспир

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 807106

Country of ref document: ES